在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMEM127 Antibody, HRP conjugated

  • 中文名稱:
    TMEM127兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào):
    CSB-PA023694LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TMEM127 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMEM127
  • 別名:
    TMEM127; Transmembrane protein 127
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane protein 127 protein (1-95AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor.
  • 基因功能參考文獻(xiàn):
    1. Of which 4 SDHB and 2 TMEM127 mutations were novel. PMID: 26960314
    2. Hereditary pheochromocytoma / paraganglioma associated with TMEM127 gene mutations has more aggressive course,bilateral adrenal involvement, higher recurrence rate, younger age at disease manifestations. PMID: 26591561
    3. We report the first case of an individual with both a pheochromocytoma and a multilocular clear cell renal cell carcinoma driven by a novel germline mutation in the TMEM127 gene, with a sibling and 2 sons with the same mutation. PMID: 25800244
    4. Tumor multicentricity, nodular adrenomedullary hyperplasia, and the occurrence of symptoms more than a decade earlier than the age at diagnosis are novel findings in TMEM127-related pheochromocytoma. PMID: 25389632
    5. A male patient with sporadic adrenal pheochromocytoma presents with a novel TMEM127 germline mutation, p. Gln139X. PMID: 23551308
    6. TMEM127 protein localizes in lysosomes in HeLa cells PMID: 21752829
    7. report shows that TMEM127 mutation plays a pathological role in pheochromocytoma in an Asian population. PMID: 22541004
    8. TMEM127 is a novel pheochromocytoma susceptibility gene.[review] PMID: 21447639
    9. TMEM127 germline mutations confer risks of extraadrenal paraganglial tumors in addition to the documented adrenal pheochromocytoma. PMID: 21613359
    10. Pathological and genomic data demonstrated that a TMEM127 gene mutation not previously described was causative of a new case of familial bilateral pheochromocytoma. PMID: 20923864
    11. Germline mutations of FP/TMEM127 were associated with pheochromocytoma but not paraganglioma and occurred in an age group frequently excluded from genetic screening algorithms; mutations disrupt intracellular distribution of the FP/TMEM127 protein. PMID: 21156949
    12. Germline mutations in TMEM127 confer susceptibility to pheochromocytoma and identify TMEM127 as a tumor suppressor gene. PMID: 20154675

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Pheochromocytoma (PCC)
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族:
    TMEM127 family
  • 組織特異性:
    Widely expressed.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 26038

    OMIM: 171300

    KEGG: hsa:55654

    STRING: 9606.ENSP00000258439

    UniGene: Hs.164303



主站蜘蛛池模板: 亚洲日韩成人无码| 中文字幕亚洲码在线| 国产成人精品aa毛片| 亚洲一区二区三区高清av| 久久婷婷综合激情亚洲狠狠| 亚洲日韩穿丝袜在线推荐| 国产精品人妻一码二码| 亚洲成a∨人片在线观看不卡| 日本又色又爽又黄的a片吻戏| 日韩内射激情视频在线播放免费 | 蜜桃av无码免费看永久| 日韩国产成人无码av毛片蜜柚| 日本一卡2卡3卡四卡精品网站| 丰满人妻熟妇乱又伦精品视| 成 人 综合 亚洲另类| 精品伊人久久久大香线蕉下载 | 国内精品自在自线| 日本一道综合久久aⅴ久久| 亚洲综合无码一区二区三区不卡| 中文字幕无码精品亚洲资源网久久 | 人人爽人人添人人超| 国产精品成人无码免费| 免费人成年激情视频在线观看| 女人的天堂a国产在线观看| 蜜臀avwww国产天堂| 内射老妇bbwx0c0ck| 香蕉欧美成人精品a∨在线观看| 国产成人无码a区在线观看视频app | 日韩av无码国产精品| 国产l精品国产亚洲区| 97久久精品人人做人人爽| 狠狠色丁香婷婷综合潮喷| 最近中文字幕免费mv在线视频| 日韩好精品视频你懂的| 极品少妇xxxx| 久久激情日本亚洲欧洲国产中文| 久久天天躁狠狠躁夜夜96流白浆 | 免费国精产品自偷自偷免费看 | 亚洲人成电影免费观看在线看| 国产精品福利一区二区| 真人抽搐一进一出gif|