在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMEM127 Antibody, FITC conjugated

  • 中文名稱:
    TMEM127兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA023694LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TMEM127 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMEM127
  • 別名:
    TMEM127; Transmembrane protein 127
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane protein 127 protein (1-95AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor.
  • 基因功能參考文獻:
    1. Of which 4 SDHB and 2 TMEM127 mutations were novel. PMID: 26960314
    2. Hereditary pheochromocytoma / paraganglioma associated with TMEM127 gene mutations has more aggressive course,bilateral adrenal involvement, higher recurrence rate, younger age at disease manifestations. PMID: 26591561
    3. We report the first case of an individual with both a pheochromocytoma and a multilocular clear cell renal cell carcinoma driven by a novel germline mutation in the TMEM127 gene, with a sibling and 2 sons with the same mutation. PMID: 25800244
    4. Tumor multicentricity, nodular adrenomedullary hyperplasia, and the occurrence of symptoms more than a decade earlier than the age at diagnosis are novel findings in TMEM127-related pheochromocytoma. PMID: 25389632
    5. A male patient with sporadic adrenal pheochromocytoma presents with a novel TMEM127 germline mutation, p. Gln139X. PMID: 23551308
    6. TMEM127 protein localizes in lysosomes in HeLa cells PMID: 21752829
    7. report shows that TMEM127 mutation plays a pathological role in pheochromocytoma in an Asian population. PMID: 22541004
    8. TMEM127 is a novel pheochromocytoma susceptibility gene.[review] PMID: 21447639
    9. TMEM127 germline mutations confer risks of extraadrenal paraganglial tumors in addition to the documented adrenal pheochromocytoma. PMID: 21613359
    10. Pathological and genomic data demonstrated that a TMEM127 gene mutation not previously described was causative of a new case of familial bilateral pheochromocytoma. PMID: 20923864
    11. Germline mutations of FP/TMEM127 were associated with pheochromocytoma but not paraganglioma and occurred in an age group frequently excluded from genetic screening algorithms; mutations disrupt intracellular distribution of the FP/TMEM127 protein. PMID: 21156949
    12. Germline mutations in TMEM127 confer susceptibility to pheochromocytoma and identify TMEM127 as a tumor suppressor gene. PMID: 20154675

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Pheochromocytoma (PCC)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族:
    TMEM127 family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 26038

    OMIM: 171300

    KEGG: hsa:55654

    STRING: 9606.ENSP00000258439

    UniGene: Hs.164303



主站蜘蛛池模板: 亚洲熟妇无码av不卡在线| 久久精品国产精品亚洲下载| 久草热8精品视频在线观看| 久久这里只有是精品23| 欧美日韩国产精品| 国色天香中文字幕在线视频| 高潮毛片无遮挡高清视频播放| 国产精品 亚洲一区二区三区| 国产老熟女狂叫对白| 亚洲中文字幕无码中文字| а√天堂资源官网在线资源| 亚洲色欲天天天堂色欲网| 日韩欧美激情兽交| 亚洲五月天综合| 中文字幕精品久久久乱码乱码 | 一区二区视频| 成人欧美一区二区三区黑人免费| 国产婷婷亚洲999精品小说 | 国内午夜国产精品小视频| 国产农村乱辈无码| 中文字幕人妻熟女人妻| 日本欧美大码a在线观看| 色伊人亚洲综合网站| 人人澡人人妻人人爽人人蜜桃麻豆 | 国产精品视频永久免费播放| 亚洲精品国精品久久99热| 成人做爰高潮片免费视频| 宝宝好涨水快流出来免费视频| 亚洲欧洲日产国码无码久久99| 免费观看啪啪黄的网站| 在线观看无码av网站永久免费| 少妇粉嫩小泬白浆流出| 中文在线а√天堂官网| 免费va人成视频网站全| 日韩av片无码一区二区不卡电影| av色欲无码人妻中文字幕| 硬了进去湿好大娇喘视频| 国内少妇偷人精品视频| 美女大量吞精在线观看456| 无人区码一码二码w358cc| 人人爽久久久噜噜噜婷婷|