在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TLK2 Antibody

TLK2 Antibody

  • 中文名稱：
    TLK2兔多克隆抗體
  • 貨號：
    CSB-PA801231LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA801231LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA801231LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA801231LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TLK2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TLK2
  • 別名：
    MGC44450 antibody; PKU alpha antibody; PKU-alpha antibody; Serine/threonine kinase antibody; Serine/threonine protein kinase tousled like 2 antibody; Serine/threonine-protein kinase tousled-like 2 antibody; TLK 2 antibody; tlk2 antibody; TLK2_HUMAN antibody; Tousled like kinase 2 antibody; Tousled-like kinase 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein kinase tousled-like 2 protein (23-234AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TLK2 Antibody (CSB-PA801231LA01HU)，的標記方式是Non-conjugated。對于TLK2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA801231LB01HU TLK2 Antibody, HRP conjugated ELISA
    FITC CSB-PA801231LC01HU TLK2 Antibody, FITC conjugated
    Biotin CSB-PA801231LD01HU TLK2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy.
  • 基因功能參考文獻：
    1. haploinsufficiency of TLK2 is the most likely underlying disease mechanism, leading to a consistent neurodevelopmental phenotype. PMID: 29861108
    2. Molecular basis of TLK2 activation and inhibition has been dissected. PMID: 29955062
    3. TLK2 is amplified in aggressive luminal breast neoplasms PMID: 27694828
    4. Tlk2 promotes Asf1A function during the DNA damage response in G2 to allow for proper restoration of chromatin structure at the break site and subsequent recovery from the arrest. PMID: 26931568
    5. Results show that TLK2 overexpression correlates with increased genome-wide copy number aberrations in breast cancer cells, impairs cell-cycle checkpoint signaling in response to DNA damage. PMID: 27489360
    6. TLK2 plays a role in Kaposi's sarcoma-associated herpesvirus reactivation. PMID: 23414760
    7. TLKs appear to be intimately linked to the pattern of resistance to DNA damage, and specifically double-strand breaks. PMID: 21647934
    8. ASF1 cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 and hASF1a by TLK kinases. PMID: 20016786

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Colocalizes with the cytoplasmic intermediate filament system during the G1 phase of the cell cycle. Present in the perinuclear region at S phase and in the nucleus at late G2.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性：
    Ubiquitous. Detected in placenta, fetal liver, kidney, pancreas, heart and skeletal muscle. Highly expressed in testis. Detected in spleen, thymus, colon, ovary, small intestine, prostate and peripheral blood leukocytes.
  • 數據庫鏈接：

    HGNC: 11842

    OMIM: 608439

    KEGG: hsa:11011

    STRING: 9606.ENSP00000275780

    UniGene: Hs.445078



主站蜘蛛池模板： 国产成人亚洲无吗淙合青草| 国产免费丝袜调教视频| 国产超薄肉色丝袜视频| 欧美性猛交xxxxx按摩欧美| 国产亚洲精品a在线观看下载| 国产精品无码制服丝袜| 大肉大捧一进一出好爽动态图| 97精品国自产在线偷拍| 久久精品娱乐亚洲领先| 少妇被躁爽到高潮无码久久| 无码专区人妻系列日韩精品| 亚洲国产成人久久久网站| 国产拍揄自揄精品视频| 国产av一区二区三区最新精品| 中文字幕一区二区三区日韩精品 | 2022国产日产欧产精品| 国模吧无码一区二区三区| 亚洲人成小说网站色在线| 两性色午夜视频免费老司机| 四虎精品免费永久免费视频| av老司机亚洲精品天堂| 国产草莓精品国产av片国产| 亚洲精品卡一卡三卡四卡乱码| 国产精品视频二区不卡| 国产97色在线 | 日韩| 亚洲国产成人久久综合人| 99久热国产精品视频尤物| 99精品久久精品一区二区| 无遮无挡三级动态图| 护士张开腿被奷日出白浆| 国产色a在线观看| 国产精品毛片一区二区| 亚洲在av极品无码天堂手机版| 337p日本欧洲亚洲大胆精筑| 亚洲区日韩精品中文字幕| 熟妇熟女乱妇乱女网站| 亚洲国产精品久久久久4婷婷 | 国产果冻豆传媒麻婆| 国自产偷精品不卡在线| 国产精品99久久不卡| 中文有码人妻字幕在线|