在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SYT11 Antibody

SYT11 Antibody

  • 中文名稱：
    SYT11兔多克隆抗體
  • 貨號：
    CSB-PA265153
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA265153(SYT11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SYT11
  • 別名：
    DKFZp781D015 antibody; KIAA0080 antibody; MGC10881 antibody; MGC17226 antibody; Synaptotagmin 11 antibody; Synaptotagmin 12 antibody; Synaptotagmin XI antibody; Synaptotagmin-11 antibody; Synaptotagmin11 antibody; Synaptotagmin12 antibody; SynaptotagminXI antibody; SYT 11 antibody; SYT 12 antibody; Syt XI antibody; Syt11 antibody; SYT11_HUMAN antibody; SYT12 antibody; SytXI antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human SYT11
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+). Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval. Plays an important role in dopamine transmission by regulating endocytosis and the vesicle-recycling process. Essential component of a neuronal vesicular trafficking pathway that differs from the synaptic vesicle trafficking pathway but is crucial for development and synaptic plasticity. In macrophages and microglia, inhibits the conventional cytokine secretion, of at least IL6 and TNF, and phagocytosis. In astrocytes, regulates lysosome exocytosis, mechanism required for the repair of injured astrocyte cell membrane. Required for the ATP13A2-mediated regulation of the autophagy-lysosome pathway.
  • 基因功能參考文獻：
    1. ATP13A2 and SYT11 form a functional network in the regulation of the autophagy-lysosome pathway, which may contribute to forms of Parkinson's Disease-associated neurodegeneration. PMID: 27278822
    2. parkin deficiency induces synaptotagmin-11 accumulation and PD-like neurotoxicity in mouse models, which is reversed by SYT11 knockdown in the SNpc or knockout of SYT11 restricted to dopaminergic neuron PMID: 29311685
    3. In summary, This study supports the existence of association between Parkinson disease and markers in or around SYT11 PMID: 26944171
    4. The genetic variations of VAMP2, Synaptotagmin XI might be indication of the relationship between these genes and idiopathic generalized epilepsy PMID: 24164654
    5. parkin interacts with and ubiquitinates synaptotagmin XI PMID: 12925569
    6. Lack of disease-causing mutations in a detailed analysis of a large sample of familial and sporadic Parkinson's disease patients argues against a major role of mutations in the synaptotagmin XI gene in PD. PMID: 15354386
    7. Excessive expression of Syt11 can be associated with schizophrenia. PMID: 17192956

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasmic vesicle membrane; Single-pass membrane protein. Perikaryon. Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein. Recycling endosome membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, phagosome. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Recycling endosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass membrane protein. Perikaryon.
  • 蛋白家族：
    Synaptotagmin family
  • 數據庫鏈接：

    HGNC: 19239

    OMIM: 608741

    KEGG: hsa:23208

    STRING: 9606.ENSP00000357307

    UniGene: Hs.32984



主站蜘蛛池模板： 国产在线欧美日韩精品一区| 精品少妇ay一区二区三区| 欧美老妇牲交videos| 日韩一区二区三区射精| 中文字幕va一区二区三区 | 亚洲欧美日韩_欧洲日韩| 亚洲精品一区二区三区影院 | 免费看国产精品3a黄的视频| 好吊射视频988gaocom| 人与嘼av免费| 国产精品久久久久9999爆乳| 国产精品无码mv在线观看 | 亚洲中文有码字幕青青| 国产精品高潮呻吟av久久男男| 亚洲国产成人久久综合区| 美女裸体自慰在线观看| 精品亚洲欧美自拍| 特级a欧美做爰片第一次| 久久不见久久见免费影院www| 中日韩高清无专码区2021| 小荡货奶真大水多好紧视频| 欧洲免费一区二区三区视频| 国产av无码国产av毛片| 色播久久人人爽人人爽人人片av | 国产亚洲精品无码成人| 欧美精品欧美人与动人物牲交| 亚洲中文字幕不卡无码| 日韩人妻无码中文字幕视频| 亚洲va中文字幕| 欧美18精品久久久无码午夜福利| 永久免费无码av在线网站| 国产精品激情| 人人妻人人澡人人爽欧美一区| 人人妻人人澡人人爽人人精品97| 亚洲日韩一中文字暮av| 亚洲成a人v欧美综合天堂麻豆| 国产无遮挡又黄又爽又色| 最新亚洲精品国偷自产在线| 免费无码午夜理论电影| 50路60路老熟妇啪啪| 国产极品白嫩精品|