在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SYT11 Antibody

SYT11 Antibody

  • 中文名稱：
    SYT11兔多克隆抗體
  • 貨號：
    CSB-PA097385
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA097385(SYT11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA097385(SYT11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SYT11
  • 別名：
    DKFZp781D015 antibody; KIAA0080 antibody; MGC10881 antibody; MGC17226 antibody; Synaptotagmin 11 antibody; Synaptotagmin 12 antibody; Synaptotagmin XI antibody; Synaptotagmin-11 antibody; Synaptotagmin11 antibody; Synaptotagmin12 antibody; SynaptotagminXI antibody; SYT 11 antibody; SYT 12 antibody; Syt XI antibody; Syt11 antibody; SYT11_HUMAN antibody; SYT12 antibody; SytXI antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human SYT11
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+). Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval. Plays an important role in dopamine transmission by regulating endocytosis and the vesicle-recycling process. Essential component of a neuronal vesicular trafficking pathway that differs from the synaptic vesicle trafficking pathway but is crucial for development and synaptic plasticity. In macrophages and microglia, inhibits the conventional cytokine secretion, of at least IL6 and TNF, and phagocytosis. In astrocytes, regulates lysosome exocytosis, mechanism required for the repair of injured astrocyte cell membrane. Required for the ATP13A2-mediated regulation of the autophagy-lysosome pathway.
  • 基因功能參考文獻：
    1. ATP13A2 and SYT11 form a functional network in the regulation of the autophagy-lysosome pathway, which may contribute to forms of Parkinson's Disease-associated neurodegeneration. PMID: 27278822
    2. parkin deficiency induces synaptotagmin-11 accumulation and PD-like neurotoxicity in mouse models, which is reversed by SYT11 knockdown in the SNpc or knockout of SYT11 restricted to dopaminergic neuron PMID: 29311685
    3. In summary, This study supports the existence of association between Parkinson disease and markers in or around SYT11 PMID: 26944171
    4. The genetic variations of VAMP2, Synaptotagmin XI might be indication of the relationship between these genes and idiopathic generalized epilepsy PMID: 24164654
    5. parkin interacts with and ubiquitinates synaptotagmin XI PMID: 12925569
    6. Lack of disease-causing mutations in a detailed analysis of a large sample of familial and sporadic Parkinson's disease patients argues against a major role of mutations in the synaptotagmin XI gene in PD. PMID: 15354386
    7. Excessive expression of Syt11 can be associated with schizophrenia. PMID: 17192956

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasmic vesicle membrane; Single-pass membrane protein. Perikaryon. Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein. Recycling endosome membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, phagosome. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Recycling endosome membrane; Single-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass membrane protein. Perikaryon.
  • 蛋白家族：
    Synaptotagmin family
  • 數據庫鏈接：

    HGNC: 19239

    OMIM: 608741

    KEGG: hsa:23208

    STRING: 9606.ENSP00000357307

    UniGene: Hs.32984



主站蜘蛛池模板： 天堂а在线中文在线新版| av无码人妻波多野结衣| 久久久中日ab精品综合| 婷婷亚洲综合五月天小说| 国产99在线 | 亚洲| 国产欧美va天堂在线电影| 国产在线乱子伦一区二区| 国产乱子伦农村xxxx| 久久国产avjust麻豆| 亚洲国产成av人天堂无码| 人妻少妇88久久中文字幕| 国产亚洲精品久久久久蜜臀| 国产亚洲成av人片在线观看| 无码免费无线观看在线视| 色yeye香蕉凹凸视频在线观看| 久人人爽人人爽人人片av| 国产毛片精品av一区二区| 成年动漫18禁无码3d动漫| 国产欧美一区二区三区免费视频| 国产精品无码成人午夜电影| 久久精品国产精油按摩| 伊人av超碰伊人久久久| 国产成人精品日本亚洲第一区| 亚洲妇女水蜜桃av网网站| 久久无码潮喷a片无码高潮| 亚洲人成电影综合网站色www| 精品丰满人妻无套内射| 浮妇高潮喷白浆视频| 久久精品无码专区免费青青| а√天堂8资源在线官网| 人妻少妇精品无码专区| 国产区又黄又硬高潮的视频| 亚洲人成在线观看网站无码| 韩国乱码伦视频免费| 99久久精品免费看国产一区二区| 亚洲精品无码久久久久av麻豆| a国产一区二区免费入口| 国产精品无码素人福利| 乱无码伦视频在线观看| 中文字幕无码乱码人妻系列蜜桃 | 国产精品久久久久久久久软件 |