在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STARD13 Antibody

STARD13 Antibody

  • 中文名稱：
    STARD13兔多克隆抗體
  • 貨號：
    CSB-PA896714LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA896714LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) STARD13 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    STARD13
  • 別名：
    46H23.2 antibody; ARHGAP37 antibody; Deleted in liver cancer 2 protein antibody; Deleted in liver cancer protein 2 antibody; DLC-2 antibody; DLC2 antibody; GT650 antibody; Rho GTPase activating protein on chromosome 13q12 antibody; Rho GTPase-activating protein antibody; STA13 antibody; STA13_HUMAN antibody; StAR related lipid transfer (START) domain containing 13 antibody; StAR-related lipid transfer protein 13 antibody; StARD13 antibody; START domain-containing protein 13 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human StAR-related lipid transfer protein 13 protein (516-679AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，STARD13 Antibody (CSB-PA896714LA01HU)，的標記方式是Non-conjugated。對于STARD13 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA896714LB01HU STARD13 Antibody, HRP conjugated ELISA
    FITC CSB-PA896714LC01HU STARD13 Antibody, FITC conjugated
    Biotin CSB-PA896714LD01HU STARD13 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
  • 基因功能參考文獻：
    1. Study elucidated StarD13 messenger RNA as a Competitive endogenous messenger RNA (ceRNA) in regulating migration and invasion of breast cancer cells. MicroRNA-125b was identified to induce metastasis of MCF-7 cells and bind with both StarD13 3'UTR and TP53INP1 3'UTR. Therefore, a ceRNA interaction between StarD13 and TP53INP1 mediated by competitively binding to miR-125b was indicated. PMID: 29146309
    2. Low STARD13 expression is associated with metastasis of breast cancer. PMID: 26985770
    3. miR-125b functions as an oncogene in gastric cancer and represents a new potential therapeutic target for gastric cancer. PMID: 27220320
    4. The tumor suppressor DLC2 and Kif1B are central components of a signaling network that guides spindle positioning, cell-cell adhesion and mitotic fidelity. PMID: 25518808
    5. Dimerization of DLC2 was required for its interaction with GKAP, which, in turn, potentiated GKAP self-association. PMID: 24938595
    6. Study describes STARD13 as a tumor suppressor playing a positive role in cancer motility. PMID: 24627003
    7. The present study further describes the role of StarD13 as a tumor suppressor as well as a Rho GAP. PMID: 24253896
    8. Importance of the regulation of RhoA activity in focal adhesions of astrocytoma cells and StarD13 is a GAP playing a major role in this process. PMID: 24333506
    9. In the present review, we discuss the family of RhoGTPases, their regulation and their RhoGAPs, focusing mainly on STARD13. [review] PMID: 23316797
    10. RhoGAP protein Stard13 is an essential regulator of pancreas tissue architecture in the mammalian embryo; Stard13 acts by regulating Rho signalling spatially and temporally during pancreas development. PMID: 23175628
    11. Authors detected an increase in p-ERK in StarD13 knockdown cells, uncovering a potential link between Rho GTPases and ERK activation. PMID: 22614672
    12. role of miR-125b in pro-metastasis by targeting STARD13 PMID: 22693547
    13. DLC2 inhibits the activity of Raf-1-ERK1/2-p70S6K via its RhoGAP function, resulting in the suppression of cell growth. PMID: 20629949
    14. has GAP activity specific for RhoA and Cdc42; inhibits the Rho mediated assembly of actin stress fibers in cultured cells and is underexpressed in hepatocellular carcinoma tissues PMID: 12531887
    15. underexpression is associated with poor prognosis in patients with hepatocellular carcinoma PMID: 18651974

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet.
  • 組織特異性：
    Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
  • 數據庫鏈接：

    HGNC: 19164

    OMIM: 609866

    KEGG: hsa:90627

    STRING: 9606.ENSP00000338785

    UniGene: Hs.156551



主站蜘蛛池模板： 欧美老熟妇欲乱高清视频| 久久天天躁狠狠躁夜夜爽| 欧美性大战久久久久xxx| 一本色道久久hezyo无码| 久久99久久99精品中文字幕| 成人h动漫精品一区二区| 国内精品综合久久久40p| 日产a一a区二区www| 日本中文字幕在线| 久久99精品久久久久久噜噜| 精品偷拍被偷拍在线观看| 亚洲免费视频免在线观看| 极品少妇xxxx精品少妇偷拍| 国产97在线 | 日韩| 双腿高潮抽搐喷白浆视频| 国产人妻人伦精品久久久| 久久久国产打桩机| 国产成人午夜福利在线观看| 麻豆日产精品卡2卡3卡4卡5卡| 中国真实偷乱视频| 亚洲 欧美 偷自乱 图片| 亚洲在av人极品无码| 国产在线观看无码不卡| av午夜福利一片免费看久久| 欧美成人精品第一区二区三区| 日韩成人无码| 综合精品欧美日韩国产在线| av无码免费永久在线观看| 久久国产精品波多野结衣av| 国产精品不卡无码av在线播放| 国产精品毛片在线完整版| 中国白嫩丰满人妻videos| 欧洲成人一区二区三区| 真人做受试看120分钟小视频 | 久久国产偷任你爽任你| 西西人体444www高清大胆| 成人欧美一区二区三区1314| av在线亚洲欧洲日产一区二区| 亚洲色大成影网站www永久 | 少妇无码一区二区二三区| 精品一卡二卡三卡四卡网站|