在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SPR Antibody

  • 中文名稱:
    SPR兔多克隆抗體
  • 貨號:
    CSB-PA022605GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SPR
  • 別名:
    OTTHUMP00000160199 antibody; SDR38C1 antibody; Sepiapterin reductase (7,8 dihydrobiopterin:NADP+ oxidoreductase) antibody; Sepiapterin reductase antibody; Short chain dehydrogenase/reductase family 38C, member 1 antibody; SPR antibody; SPRE_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SPR
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
  • 基因功能參考文獻:
    1. The allele frequencies for the SPR c.596-2A > G (0.7%) polymorphism is not a major cause of Parkinson's disease in the Maltese. PMID: 27613114
    2. We earlier presented evidence for a physical interaction between ODC and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded Neuroblastoma cell proliferation. PMID: 26093909
    3. new homozygous mutation in the SPR gene was found in two sisters with dopa-responsive dystonia PMID: 24588500
    4. Authors identified SPR as a novel regulator of ODC enzyme activity and, based on clinical evidence, present a model in which SPR drives ODC-mediated malignant progression in neuroblastoma. PMID: 24096079
    5. SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms PMID: 23640889
    6. SRD can manifest as early-onset parkinsonism, widening the spectrum of the disease phenotype and adding to the genetic heterogeneity of the disease PMID: 22018912
    7. this large association study for the SPR gene revealed no association for Parkinson disease worldwide. PMID: 21782285
    8. We examine the sleep, sleep-wake rhythms, CSF neurotransmitters, and melatonin profile in a patient with sepiapterin reductase deficiency. PMID: 20337188
    9. haploinsufficiency of SPR can be a rare cause of dopa-responsive dystonia PMID: 15241655
    10. Potentially modulates the onset of or risk for Parkinson's disease. PMID: 16443856
    11. Although association of SPR to Parkinson's disease (PD) is not strong enough to support that this is the PARK3 gene, this study further implicates a role for SPR in idiopathic PD. PMID: 17270157
    12. Genomic DNA revealed the same homozygous point mutation introducing a premature stop codon in the SPR gene in 2 siblings. PMID: 18502672
    13. This reduced transcription rate for SPR promoter haplotypes 2 and 3 may impact on antidepressant response and susceptibility to bipolar disorder. PMID: 19415819

    顯示更多

    收起更多

  • 相關疾病:
    Dystonia, DOPA-responsive, due to sepiapterin reductase deficiency (DRDSPRD)
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Sepiapterin reductase family
  • 數據庫鏈接:

    HGNC: 11257

    OMIM: 182125

    KEGG: hsa:6697

    STRING: 9606.ENSP00000234454

    UniGene: Hs.301540



主站蜘蛛池模板: 日韩制服国产精品一区| 国产成人精品三上悠亚| 成人免费的视频| 免费观看潮喷到高潮中文字幕| 国产99视频精品免费视频6| 天天综合爱天天综合色| 国产佗精品一区二区三区| 成av免费大片黄在线观看| 国产精品人成视频国模| 少妇爱做高清免费视频| 激情爆乳一区二区三区| 国产成人无码网站| 国产成人av免费网址| 麻豆专媒体一区二区| 狠狠噜天天噜日日噜视频跳一跳| av午夜福利一片免费看久久| 久久久精品人妻一区亚美研究所| 欧美一道本一区二区三区| 日本边添边摸边做边爱边| 精品无码黑人又粗又大又长| 久久久亚洲欧洲日产国产成人无码| 免费人成网站在线观看欧美| 男女啪啦猛视频免费| 欧美大荫蒂毛茸茸视频| 人妻熟女一二三区夜夜爱| 国产一区二区三区在线电影 | 思思久久精品一本到99热| 亚洲国产av一区二区三区四区| 国产成人精品三上悠亚| 久久99久久99小草精品免视看| 日产精品一二三区| 国产麻豆成人传媒免费观看 | 国产午夜精华2020在线| 久久久综合九色合综| 少妇人妻偷人精品视蜜桃| 风韵人妻丰满熟妇老熟女| 国产农村乱辈无码| 好了av四色综合无码| 亚洲色播爱爱爱爱爱爱爱| 天天狠天天透天干天天| 一本久道综合色婷婷五月|