在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPR Antibody

SPR Antibody

  • 中文名稱：
    SPR兔多克隆抗體
  • 貨號：
    CSB-PA262747
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA262747(SPR Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA262747(SPR Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human chromaffin cell tumor tissue, lovo cells, Primary antibody: CSB-PA262747(SPR Antibody) at dilution 1/1500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SPR
  • 別名：
    OTTHUMP00000160199 antibody; SDR38C1 antibody; Sepiapterin reductase (7,8 dihydrobiopterin:NADP+ oxidoreductase) antibody; Sepiapterin reductase antibody; Short chain dehydrogenase/reductase family 38C, member 1 antibody; SPR antibody; SPRE_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SPR
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
  • 基因功能參考文獻：
    1. The allele frequencies for the SPR c.596-2A > G (0.7%) polymorphism is not a major cause of Parkinson's disease in the Maltese. PMID: 27613114
    2. We earlier presented evidence for a physical interaction between ODC and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded Neuroblastoma cell proliferation. PMID: 26093909
    3. new homozygous mutation in the SPR gene was found in two sisters with dopa-responsive dystonia PMID: 24588500
    4. Authors identified SPR as a novel regulator of ODC enzyme activity and, based on clinical evidence, present a model in which SPR drives ODC-mediated malignant progression in neuroblastoma. PMID: 24096079
    5. SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms PMID: 23640889
    6. SRD can manifest as early-onset parkinsonism, widening the spectrum of the disease phenotype and adding to the genetic heterogeneity of the disease PMID: 22018912
    7. this large association study for the SPR gene revealed no association for Parkinson disease worldwide. PMID: 21782285
    8. We examine the sleep, sleep-wake rhythms, CSF neurotransmitters, and melatonin profile in a patient with sepiapterin reductase deficiency. PMID: 20337188
    9. haploinsufficiency of SPR can be a rare cause of dopa-responsive dystonia PMID: 15241655
    10. Potentially modulates the onset of or risk for Parkinson's disease. PMID: 16443856
    11. Although association of SPR to Parkinson's disease (PD) is not strong enough to support that this is the PARK3 gene, this study further implicates a role for SPR in idiopathic PD. PMID: 17270157
    12. Genomic DNA revealed the same homozygous point mutation introducing a premature stop codon in the SPR gene in 2 siblings. PMID: 18502672
    13. This reduced transcription rate for SPR promoter haplotypes 2 and 3 may impact on antidepressant response and susceptibility to bipolar disorder. PMID: 19415819

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Dystonia, DOPA-responsive, due to sepiapterin reductase deficiency (DRDSPRD)
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sepiapterin reductase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11257

    OMIM: 182125

    KEGG: hsa:6697

    STRING: 9606.ENSP00000234454

    UniGene: Hs.301540



主站蜘蛛池模板： 亚洲日韩v无码中文字幕| 99精品国产福久久久久久| 国产精品成人av在线观看| 国产午夜无码视频在线观看| 国产精品久久久久秋霞鲁丝| 77se77亚洲欧美在线| 人人爽人人爽人人片av亚洲| 国产精品无码翘臀在线观看| 亚洲不乱码卡一卡二卡4卡5| 欧美日韩人妻精品一区二区在线 | 亚洲国产精品久久久久秋霞影院| 2012中文字幕在线视频| 亚洲中文有码字幕日本| 亚洲免费观看视频| 在线观看免费人成视频色9| 国产精品进线69影院| 少妇爽到呻吟的视频| 激情影院内射美女| 亚洲精品蜜桃久久久久久| 香蕉蕉亚亚洲aav综合| 2021久久最新国产精品| 性色做爰片在线观看ww| av大片在线无码永久免费| 色偷偷人人澡久久超碰97| 国产精品久久久爽爽爽麻豆色哟哟| 亂倫近親相姦中文字幕| 动漫精品专区一区二区三区不卡| 免费午夜理论不卡| 中文字字幕人妻中文| 成人乱人乱一区二区三区| 无码av免费一区二区三区四区 | 中文字幕精品久久久久人妻红杏| 免费无码av一区二区三区| 亚洲精品国产精品乱码视色| av蓝导航精品导航| 中文字幕亚洲综合久久蜜桃| 国产日产亚洲系列最新| 无码写真精品永久福利在线| 国产精品自在拍首页视频8| 久久99亚洲精品久久99果 | 77777亚洲午夜久久多人|