在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SPR Antibody

SPR Antibody

  • 中文名稱：
    SPR兔多克隆抗體
  • 貨號：
    CSB-PA262747
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA262747(SPR Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA262747(SPR Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human chromaffin cell tumor tissue, lovo cells, Primary antibody: CSB-PA262747(SPR Antibody) at dilution 1/1500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SPR
  • 別名：
    OTTHUMP00000160199 antibody; SDR38C1 antibody; Sepiapterin reductase (7,8 dihydrobiopterin:NADP+ oxidoreductase) antibody; Sepiapterin reductase antibody; Short chain dehydrogenase/reductase family 38C, member 1 antibody; SPR antibody; SPRE_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SPR
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
  • 基因功能參考文獻：
    1. The allele frequencies for the SPR c.596-2A > G (0.7%) polymorphism is not a major cause of Parkinson's disease in the Maltese. PMID: 27613114
    2. We earlier presented evidence for a physical interaction between ODC and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC enzyme activity and impeded Neuroblastoma cell proliferation. PMID: 26093909
    3. new homozygous mutation in the SPR gene was found in two sisters with dopa-responsive dystonia PMID: 24588500
    4. Authors identified SPR as a novel regulator of ODC enzyme activity and, based on clinical evidence, present a model in which SPR drives ODC-mediated malignant progression in neuroblastoma. PMID: 24096079
    5. SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms PMID: 23640889
    6. SRD can manifest as early-onset parkinsonism, widening the spectrum of the disease phenotype and adding to the genetic heterogeneity of the disease PMID: 22018912
    7. this large association study for the SPR gene revealed no association for Parkinson disease worldwide. PMID: 21782285
    8. We examine the sleep, sleep-wake rhythms, CSF neurotransmitters, and melatonin profile in a patient with sepiapterin reductase deficiency. PMID: 20337188
    9. haploinsufficiency of SPR can be a rare cause of dopa-responsive dystonia PMID: 15241655
    10. Potentially modulates the onset of or risk for Parkinson's disease. PMID: 16443856
    11. Although association of SPR to Parkinson's disease (PD) is not strong enough to support that this is the PARK3 gene, this study further implicates a role for SPR in idiopathic PD. PMID: 17270157
    12. Genomic DNA revealed the same homozygous point mutation introducing a premature stop codon in the SPR gene in 2 siblings. PMID: 18502672
    13. This reduced transcription rate for SPR promoter haplotypes 2 and 3 may impact on antidepressant response and susceptibility to bipolar disorder. PMID: 19415819

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Dystonia, DOPA-responsive, due to sepiapterin reductase deficiency (DRDSPRD)
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sepiapterin reductase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11257

    OMIM: 182125

    KEGG: hsa:6697

    STRING: 9606.ENSP00000234454

    UniGene: Hs.301540



主站蜘蛛池模板： 亚洲人成无码网站18禁10| 色夜码无码av网站| 国产拍揄自揄免费观看| 国产亚洲精品久久久久久老妇小说 | 图片小说视频一区二区| 欧美人与禽zoz0性伦交| 在线播放真实国产乱子伦| 国产又粗又猛又爽的视频a片| 国产成人午夜福利免费无码r| 无码av免费网站| 欧美内射rape视频| 亚洲人成影院在线无码按摩店| 播五月开心婷婷欧美综合| 国产极品久久久久久久久| 午夜三级a三级三点在线观看| 亚洲熟妇少妇任你躁在线观看无码 | 精品麻豆国产色欲色欲色欲www| 精品四虎国产在免费观看| 2021国产精品午夜久久| 欧洲熟妇精品视频| 欧美精品国产aⅴ一区二区在线| 在线观看麻豆国产成人av在线播放 | 香蕉啪视频在线观看视频久| 久久九九国产精品怡红院| 国产97色在线 | 亚洲| 国产精品无码专区在线观看| 无遮挡男女激烈动态图| 国产一国产aa毛片| 国产日韩欧美| 伊人久久大香线蕉av波多野结衣| 亚洲精品中文字幕久久久久下载| 拍真实国产伦偷精品| 人妻少妇被猛烈进入中文字幕| 亚洲欧美色αv在线影视| 国产精品va无码二区| 熟女视频一区二区在线观看| 和岳每晚弄的高潮嗷嗷叫视频| 中文字幕无码日韩欧免费软件 | 成人欧美一区二区三区1314| 女人被躁到高潮免费视频| 国语自产拍无码精品视频在线|