在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SNX5 Antibody

SNX5 Antibody

  • 中文名稱：
    SNX5兔多克隆抗體
  • 貨號：
    CSB-PA022380GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    0910001N05Rik antibody; 1810032P22Rik antibody; AU019504 antibody; D2Ertd52e antibody; FLJ10931 antibody; OTTHUMP00000030340 antibody; OTTHUMP00000062927 antibody; OTTMUSP00000003367 antibody; OTTMUSP00000003368 antibody; RP11-504H3.2 antibody; RP23-35E16.2 antibody; snoRNA MBI-43 antibody; SNX 5 antibody; SNX5 antibody; SNX5_HUMAN antibody; Sorting nexin 5 antibody; Sorting nexin-5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SNX5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Does not have in vitro vesicle-to-membrane remodeling activity. Involved in retrograde transport of lysosomal enzyme receptor IGF2R. May function as link between endosomal transport vesicles and dynactin (Probable). Plays a role in the internalization of EGFR after EGF stimulation (Probable). Involved in EGFR endosomal sorting and degradation; the function involves PIP5K1C isoform 3 and is retromer-independent. Together with PIP5K1C isoform 3 facilitates HGS interaction with ubiquitinated EGFR, which initiates EGFR sorting to intraluminal vesicles (ILVs) of the multivesicular body for subsequent lysosomal degradation (Probable). Involved in E-cadherin sorting and degradation; inhibits PIP5K1C isoform 3-mediated E-cadherin degradation. Plays a role in macropinocytosis.
  • 基因功能參考文獻：
    1. High SNX5 expression is associated with alphavirus infections. PMID: 29743363
    2. sorting nexin 5 (SNX5), a component of the retromer and part of the retrograde transport pathway, interacts with UL35 proteins. binding of UL35 proteins to SNX5 was required for efficient viral replication and for transport of the most abundant cytomegalovirus glycoprotein B to the cytoplasmic viral assembly center. PMID: 29444945
    3. The Chlamydia trachomatis IncE binding site is unique to human SNX5 and related family members SNX6 and SNX32. PMID: 28226239
    4. Sorting nexin 5 and dopamine d1 receptor regulate the expression of the insulin receptor in human renal proximal tubule cells PMID: 25825816
    5. internalization of agonist-activated D1R is regulated by both SNX5 and GRK4, and that SNX5 is critical to the recycling of the receptor to the plasma membrane PMID: 23195037
    6. Data indicate induction of caspase-2 by sorting nexin 5 (SNX5) in papillary thyroid carcinoma PMID: 22486813
    7. SNX5 is localized to a subdomain of the early endosomes and is recruited to the cell membrane following EGF stimulation. PMID: 15561769
    8. SNX5 and SNX6 may constitute functional equivalents of Vps17p in mammalian retromer PMID: 17148574
    9. DOCK180 regulates CI-MPR trafficking via SNX5 and this function is independent of its guanine nucleotide exchange factor activity toward Rac1 PMID: 18596235

    顯示更多

    收起更多

  • 亞細胞定位：
    Endosome. Early endosome. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle.
  • 蛋白家族：
    Sorting nexin family
  • 數據庫鏈接：

    HGNC: 14969

    OMIM: 605937

    KEGG: hsa:27131

    STRING: 9606.ENSP00000366988

    UniGene: Hs.316890



主站蜘蛛池模板： 最新的国产成人精品2022| 久久久久久亚洲精品| 一区二区三区无码被窝影院| 中文字幕无码不卡免费视频| 亚洲中文字幕码在线电影| 日本无卡码高清免费v| 50岁熟妇大白屁股真爽| 久久婷婷五月综合色丁香| 久久久久国产精品人妻aⅴ毛片| 国内精品久久久久久久影院| 宝贝腿开大点我添添公视频免费 | 人人超人人超碰超国产97超碰| 韩产日产国产欧产| 国产成人乱色伦区| 牛和人交videos欧美| 韩国日本三级在线观看| 久久综合亚洲色hezyo国产| 亚洲日韩欧美一区久久久久我| 国产日韩欧美亚欧在线观看| 国产免码va在线观看免费 | 无码国产精品高清免费| 精品久久久无码人妻中文字幕豆芽| 日本丰满熟妇videossex8k| 亚洲这里只有久热精品伊人 | 中文字幕丰满乱子伦无码专区| 欧美孕妇乳喷奶水在线观看| 国产免费人成在线视频网站| 久久久久久久综合日本| 国产精品白丝喷水在线观看 | 亚洲国产午夜精品理论片妓女| 午夜福利视频1692| 2024av天堂手机在线观看| 少妇白浆高潮无码免费区| 99精品热在线在线观看视频| 激情航班h版在线观看| 18禁无遮挡免费视频网站| 无码中文av有码中文a| 国产精品久久久久电影网| 国产精品亚韩精品无码a在线 | 亚洲女教师丝祙在线播放 | 国产精品久久久久久久久久|