在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC6A19 Antibody

SLC6A19 Antibody

  • 中文名稱：
    SLC6A19兔多克隆抗體
  • 貨號：
    CSB-PA731656LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA731656LA01HU diluted at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA731656LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA731656LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC6A19 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    SLC6A19 antibody; B0AT1 antibody; Sodium-dependent neutral amino acid transporter B(0)AT1 antibody; Solute carrier family 6 member 19 antibody; System B(0) neutral amino acid transporter AT1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sodium-dependent neutral amino acid transporter B(0)AT1 protein (326-413AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SLC6A19 Antibody (CSB-PA731656LA01HU)，的標記方式是Non-conjugated。對于SLC6A19 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA731656LB01HU SLC6A19 Antibody, HRP conjugated ELISA
    FITC CSB-PA731656LC01HU SLC6A19 Antibody, FITC conjugated
    Biotin CSB-PA731656LD01HU SLC6A19 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity.
  • 基因功能參考文獻：
    1. SIT1, B(0)AT1 and ACE2 were co-localized in the brush-border membrane of small intestine enterocytes. PMID: 25534429
    2. PKB/Akt up-regulates SLC6A19 activity, which may foster amino acid uptake into PKB/Akt-expressing epithelial and tumor cells. PMID: 23234856
    3. JAK2 up-regulates SLC6A19 activity which may foster amino acid uptake into JAK2 expressing cells. PMID: 21964291
    4. Average loss of solute carrier expression was similar in acute tubular necrosis (77%) and T cell-mediated rejection (75%) with high correlation of individual transcripts. PMID: 20883558
    5. A novel SLC6A19 gene mutation is associated with late-onset seizures in a Korean patient with Hartnup disorder. PMID: 20399395
    6. We identified six mutations in SLC6A19 that cosegregated with disease in the predicted recessive manner, with most affected individuals being compound heterozygotes. PMID: 15286788
    7. One mutation, the D173N allele, is present in 42% of Hartnup chromosomes from apparently unrelated families from both Australia and North America. PMID: 17555458
    8. Hartnup disorder is allelically heterogeneous with two mutated SLC6A19 allele. PMID: 18484095
    9. These findings suggest that the rare SLC6A19-MS7 allele may be a risk factor for hypertension. PMID: 18671945
    10. Suggest that amino acid transporters B(0)AT1 and b(0,+)AT are involved in the reabsorption of L-citrulline in the kidney, at least in part, by mediating the apical membrane transport of L-citrulline in renal tubule cells. PMID: 19322909
    11. novel homozygous mutation of G284R in the transmembrane domain of the SLC6A19 transporter found in the proband, with typical dermatologic and neurologic manifestations and increased levels of urinary neutral amino acids PMID: 19335424
    12. Observational study of gene-disease association. (HuGE Navigator) PMID: 18671945

    顯示更多

    收起更多

  • 相關疾病：
    Hartnup disorder (HND); Hyperglycinuria (HG); Iminoglycinuria (IG)
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A19 subfamily
  • 組織特異性：
    Robust expression in kidney and small intestine, with minimal expression in pancreas. Also expressed in stomach, liver, duodenum, ileocecum, colon and prostate. Not detected in testis, whole brain, cerebellum, fetal liver, spleen, skeletal muscle, uterus,
  • 數據庫鏈接：

    HGNC: 27960

    OMIM: 138500

    KEGG: hsa:340024

    STRING: 9606.ENSP00000305302

    UniGene: Hs.481478



主站蜘蛛池模板： 亚洲欧洲日韩国内高清| 无套内谢老熟女| 熟妇人妻无码中文字幕老熟妇| 成人无码潮喷在线观看| 免费又黄又爽又猛的毛片| 久久人人97超碰国产精品| 亚洲日本成本人观看| 色婷婷av久久久久久久| 成人亚洲欧美在线观看| 让少妇高潮无乱码高清在线观看| 欧美毛多水多肥妇| av色综合久久天堂av色综合在| 国产精品色情国产三级在| 亚洲国产成人精品无码区蜜柚| 色吊丝中文字幕| 欧美孕妇变态重口另类| 午夜高清在线无码| av片亚洲国产男人的天堂| 国产精品丝袜高跟鞋| 偷拍区清纯另类丝袜美腿| 中无码人妻丰满熟妇啪啪| 麻豆专媒体一区二区| 精品国产一区二区三区四区| 国产肥白大熟妇bbbb| 亚洲熟妇久久国内精品| 精品久久久久中文字幕app| 国产精品美女久久久网站 | 无人区一线二线三线乱码| 国精产品一区一区三区| 色拍拍在线精品视频| 亚洲欧洲av一区二区久久| 97人摸人人澡人人人超碰| 亚洲成a人片在线观看www| 3p人妻少妇对白精彩视频| 亚洲国产精品无码一区二区三区| 激情内射亚州一区二区三区爱妻| 日本理伦片午夜理伦片| 精品一区二区三区国产在线观看| 大色综合色综合网站| 国产精品久久国产精品99 gif| 亚洲香蕉aⅴ视频在线播放|