在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SHC3 Antibody

SHC3 Antibody

  • 中文名稱：
    SHC3兔多克隆抗體
  • 貨號：
    CSB-PA838779LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: U87 whole cell lysate, Mouse lung tissue
      All lanes: SHC3 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 65, 52 kDa
      Observed band size: 65 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SHC3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    N SHC antibody; N-Shc antibody; Neuronal Shc antibody; NSHC antibody; Protein Rai antibody; Rai antibody; SH2 domain protein C3 antibody; SHC (Src homology 2 domain containing) transforming protein 3 antibody; SHC adaptor protein 3 antibody; SHC protein C antibody; SHC-like protein, neuronal antibody; SHC-transforming protein 3 antibody; SHC-transforming protein C antibody; Shc3 antibody; Shc3 p51 antibody; SHC3_HUMAN antibody; SHCC antibody; Src homology 2 domain-containing transforming protein antibody; Src homology 2 domain-containing-transforming protein C3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human SHC-transforming protein 3 protein (323-468AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，SHC3 Antibody (CSB-PA838779LA01HU)，的標(biāo)記方式是Non-conjugated。對于SHC3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA838779LB01HU SHC3 Antibody, HRP conjugated ELISA
    FITC CSB-PA838779LC01HU SHC3 Antibody, FITC conjugated
    Biotin CSB-PA838779LD01HU SHC3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • 基因功能參考文獻：
    1. High SHC3 expression is associated with glioblastoma. PMID: 25062668
    2. Rai (ShcC/N-Shc), a member of the family of Shc-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells. PMID: 22311806
    3. Polymorphism in RAI and CD3EAP are associated with outcome of myeloma patients treated with high dose treatment. PMID: 21046104
    4. amplification of SHC3 and EDG3 genes suggests that the two proteins co-operate and are important for ependymomas in vivo. PMID: 19748727
    5. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. PMID: 11877420
    6. ALK-ShcC signal activation, possibly caused by co-amplification with the N-myc gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK kinase. PMID: 12185581
    7. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. PMID: 12242309
    8. ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma cells PMID: 15735675
    9. The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells. PMID: 15870690
    10. data suggest that RAI (ShcC/H-Shc)is a critical substrate for RET oncoproteins in thyroid carcinomas PMID: 15940252
    11. 11 SNPs within SHC3 were examined to determine the association with nicotine dependence (ND) in either African-Americans (AA) or European-Americans (EA); three SNPs for AAs and one for EAs were significantly associated with at least one ND. PMID: 17179996
    12. shcc is expressed in the human gut, especially in the enteric glial cells PMID: 17919311
    13. ShcC is a therapeutic target that might induce differentiation in the aggressive type of neuroblastomas. PMID: 18997821

    顯示更多

    收起更多

  • 組織特異性：
    Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, me
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18181

    OMIM: 605263

    KEGG: hsa:53358

    STRING: 9606.ENSP00000364995

    UniGene: Hs.292737



主站蜘蛛池模板： 亚洲精品久久久久久久蜜桃| 青青视频免费观看免费| 国产精品久久久久久久久久免费| 成人国产精品一区二区网站公司| 婷婷久久综合九色综合绿巨人| 国产成人精品久久一区二区 | 亚洲aⅴ永久无码一区二区三区| 久久理论片午夜琪琪电影院| 国产一在线精品一区在线观看 | 国产未发育呦交视频| 午夜福利麻豆国产精品| 免费无码午夜福利片69| 中国china露脸自拍性hd| 国内老熟妇对白hdxxxx| 国产欧美日韩一区2区| 九九久久精品国产免费看小说| 大肉大捧一进一出好爽视频mba| 国产成人无码专区| 色欲天天婬色婬香综合网完整版 | 天天看片天天av免费观看| 亚洲色国产欧美日韩| 久久99精品国产麻豆宅宅| 国内精品伊人久久久久av| 久久国产欧美成人av| 日本va在线视频播放| 中文字幕亚洲日韩无线码| 午夜亚洲乱码伦小说区69堂| 视频二区丝袜国产欧美日韩| 国产精品久久久久aaaa| 亚洲精品国产精品乱码视色| 欧美高潮喷水大叫| 精品久久久无码人妻中文字幕豆芽| 天躁夜夜躁狼狠躁| 国产成人av无码精品天堂| 草裙社区精品视频三区免费看| 蜜臀国产在线视频| 国产人成视频在线视频| 热久久99这里有精品综合久久 | 成人性生交大片免费看中文| 少妇的肉体k8经典| 国产高清av喷水白丝护士|