在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SHC3 Antibody, FITC conjugated

  • 中文名稱:
    SHC3兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA838779LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SHC3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    N SHC antibody; N-Shc antibody; Neuronal Shc antibody; NSHC antibody; Protein Rai antibody; Rai antibody; SH2 domain protein C3 antibody; SHC (Src homology 2 domain containing) transforming protein 3 antibody; SHC adaptor protein 3 antibody; SHC protein C antibody; SHC-like protein, neuronal antibody; SHC-transforming protein 3 antibody; SHC-transforming protein C antibody; Shc3 antibody; Shc3 p51 antibody; SHC3_HUMAN antibody; SHCC antibody; Src homology 2 domain-containing transforming protein antibody; Src homology 2 domain-containing-transforming protein C3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human SHC-transforming protein 3 protein (323-468AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • 基因功能參考文獻:
    1. High SHC3 expression is associated with glioblastoma. PMID: 25062668
    2. Rai (ShcC/N-Shc), a member of the family of Shc-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells. PMID: 22311806
    3. Polymorphism in RAI and CD3EAP are associated with outcome of myeloma patients treated with high dose treatment. PMID: 21046104
    4. amplification of SHC3 and EDG3 genes suggests that the two proteins co-operate and are important for ependymomas in vivo. PMID: 19748727
    5. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. PMID: 11877420
    6. ALK-ShcC signal activation, possibly caused by co-amplification with the N-myc gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK kinase. PMID: 12185581
    7. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. PMID: 12242309
    8. ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma cells PMID: 15735675
    9. The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells. PMID: 15870690
    10. data suggest that RAI (ShcC/H-Shc)is a critical substrate for RET oncoproteins in thyroid carcinomas PMID: 15940252
    11. 11 SNPs within SHC3 were examined to determine the association with nicotine dependence (ND) in either African-Americans (AA) or European-Americans (EA); three SNPs for AAs and one for EAs were significantly associated with at least one ND. PMID: 17179996
    12. shcc is expressed in the human gut, especially in the enteric glial cells PMID: 17919311
    13. ShcC is a therapeutic target that might induce differentiation in the aggressive type of neuroblastomas. PMID: 18997821

    顯示更多

    收起更多

  • 組織特異性:
    Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, me
  • 數據庫鏈接:

    HGNC: 18181

    OMIM: 605263

    KEGG: hsa:53358

    STRING: 9606.ENSP00000364995

    UniGene: Hs.292737



主站蜘蛛池模板: 色欲香天天天综合网站| 色两性网欧美| 久久久国产精品麻豆a片| 久久亚洲中文字幕精品一区 | 曰批免费视频播放免费直播| 国产成人人综合亚洲欧美丁香花| 久青草国产在视频在线观看| 在线精品视频一区二区三区| 无套内内射视频网站| 肥臀浪妇太爽了快点再快点| 亚洲精品一区二区玖玖爱| 国产又粗又猛又爽的视频a片| 肉色丝袜足j视频国产| 一区二区传媒有限公司| 久久天天躁狠狠躁夜夜avapp| 中文字幕无码日韩专区免费| 久久九九精品国产综合喷水| 国产欧美在线亚洲一区| 亚洲 欧美 日韩 综合aⅴ视频| 女人爽到高潮免费看视频| 成人精品一区日本无码网站| 久久99亚洲含羞草影院| 精品无码成人网站久久久久久| 特级毛片a片久久久久久| 精品久久久久久久久久久aⅴ| 欧美性xxxxx极品少妇| 女狠狠噜天天噜日日噜| 蜜桃av麻豆av果冻传媒| 日本va欧美va欧美va精品 | 日韩av高潮喷水在线观看| 成熟妇女性成熟满足视频| 久久人人爽人人爽人人片av东京热| 中文精品无码中文字幕无码专区| 国产69囗曝吞精在线视频| 麻豆国产原创视频在线播放| 精品人妻少妇一区二区| 国产在视频线精品视频| 做爰高潮视频免费的看| 无码人妻久久1区2区3区| 亚洲aⅴ无码专区在线观看q| 亚洲熟妇无码另类久久久 |