在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SENP8 Antibody

SENP8 Antibody

  • 中文名稱：
    SENP8兔多克隆抗體
  • 貨號(hào)：
    CSB-PA822251HA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SENP8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SENP8
  • 別名：
    cysteine 2 antibody; DEN 1 antibody; DEN1 antibody; Deneddylase 1 antibody; Deneddylase-1 antibody; FKSG8 antibody; HsT17512 antibody; NEDD 8 specific protease 1 antibody; NEDD8 specific protease cysteine 2 antibody; NEDD8-specific protease 1 antibody; NEDP 1 antibody; NEDP1 antibody; Protease antibody; Protease,聽(tīng)cysteine聽(tīng)2 antibody; PRSC2 antibody; SENP8 antibody; SENP8_HUMAN antibody; Sentrin / SUMO specific protease SENP 8 antibody; Sentrin-specific protease 8 antibody; Sentrin/SUMO-specific protease SENP8 antibody; SUMO sentrin specific protease family member 8 antibody; SUMO/sentrin peptidase family member; NEDD8 specific antibody; SUMO/sentrin specific peptidase family member 8 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Sentrin-specific protease 8 protein (1-212AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，SENP8 Antibody (CSB-PA822251HA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SENP8 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA822251HB01HU SENP8 Antibody, HRP conjugated ELISA
    FITC CSB-PA822251HC01HU SENP8 Antibody, FITC conjugated
    Biotin CSB-PA822251HD01HU SENP8 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
  • 基因功能參考文獻(xiàn)：
    1. Furthermore, the authors characterized SENP8/DEN1 as the protease that counteracts Ubc12 auto-neddylation, and observed aberrant neddylation of Ubc12 and other NEDD8 conjugation pathway components in SENP8-deficient cells. PMID: 28475037
    2. In endothelial dysfunction, HDAC2 levels were reciprocally regulated by ectopic expression of NEDD8 and the de-NEDDylating enzyme SENP8. PMID: 25655932
    3. Data indicate that overexpression of SENP8, a NEDD8-specific cysteine protease, resulted in deNEDDylation of E2F1 and promoted its transactivation activity at the p73 gene. PMID: 23001041
    4. We analyzed whether CSN1 alone can increase DEN1 degradation in HeLa cells.these data suggest that the COP9 signalosome supports proteasome-dependent protein degradation of DEN1/DenA in fungi and in human cells. PMID: 23408908
    5. A role for SENP8 as a central regulator of the inflammatory process is identified using knockdown and overexpression approaches. PMID: 23209320
    6. the specificity of NEDD8-specific peptidase SENP8 PMID: 22110750
    7. Data show that the stability of MDM2 is regulated by NEDD8 pathway and identify NEDP1 that deneddylates MDM2, resulting in MDM2 destabilization concomitant with p53 activation. PMID: 19784069
    8. NEDP1 is likely to play an important role in ubiquitin-mediated proteolysis by controlling the activity of SCF complexes PMID: 12730221
    9. results suggest a unique role for NEDD8-specific protease 1(DEN1) in regulating the modification of cullin 1 by Nedd8 protein PMID: 12759363
    10. X-ray structures of the human Nedd8-specific protease, Den1, in a complex with the inhibitor Nedd8 aldehyde, thus revealing a model for the tetrahedral transition state intermediate generated during proteolysis PMID: 15567417

    顯示更多

    收起更多

  • 蛋白家族：
    Peptidase C48 family
  • 組織特異性：
    Broadly expressed, with highest levels in kidney and pancreas.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 22992

    OMIM: 608659

    KEGG: hsa:123228

    STRING: 9606.ENSP00000340505

    UniGene: Hs.513002



主站蜘蛛池模板： 中文字幕乱码亚洲无线三区| 久久综合九色综合97网| 国产精品18久久久| 亚洲国产精品国自产拍电影 | 亚洲中文字幕av不卡无码| 欧美处交wwwvideos另类| 国产精品第一区揄拍无码| 久久青青草原精品国产| 新国产三级视频在线播放| 人妻少妇被粗大爽9797pw| 亚洲午夜成人久久久久久 | 日产幕无线码三区在线| 中文字幕日韩人妻不卡一区| √最新版天堂资源网在线下载| 国外亚洲成av人片在线观看| 风韵丰满熟妇啪啪区老老熟妇| 在线观看国产成人av片| 亚洲精品午夜一区人人爽| 伊人久久综合无码成人网| 国产女人好紧好爽| 男女野外做爰全过程69影院| 亚洲国产成人精品无码区花野真一| 日本丶国产丶欧美色综合| 97久久国产亚洲精品超碰热| 久久婷婷五月综合97色直播| 激情97综合亚洲色婷婷五| 丰满大肥婆肥奶大屁股 | 午夜内射中出视频| 国产欧美va天堂在线观看视频下载 | 国产第一页屁屁影院| 黄网站成人片免费视频| 亚洲自偷自拍另类小说| 夜夜嗨av一区二区三区| 国产熟女精品视频大全 | 亚欧av无码乱码在线观看性色| 国产精品久久久久9999爆乳| 国产又色又爽又黄又免费软件 | 亚洲日韩国产中文其他| 性高朝久久久久久久| 亚洲精品白浆高清久久久久久| 久久精品人妻无码一区二区三区v 国产薄丝脚交视频在线观看 |