在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SAR1B Antibody

SAR1B Antibody

  • 中文名稱：
    SAR1B兔多克隆抗體
  • 貨號：
    CSB-PA079169
  • 規格：
    ￥1100
  • 圖片：
    • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA079169(SAR1B Antibody) at dilution 1/20. (Original magnification: ×200)
    • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA079169(SAR1B Antibody) at dilution 1/20. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ANDD antibody; CMRD antibody; GTBPB antibody; GTP binding protein SAR1b antibody; GTP binding protein Sara antibody; GTP-binding protein B antibody; GTP-binding protein SAR1B antibody; SAR1 gene homolog B (S. cerevisiae) antibody; SAR1 homolog B antibody; SAR1a gene homolog 2 antibody; SAR1B antibody; SAR1B_HUMAN antibody; SARA2 antibody; SARB antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human SAR1B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex. Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis.
  • 基因功能參考文獻：
    1. Study data suggest that SAR1A and SAR1B are the critical regulators of trafficking of Nav1.5. Moreover, SAR1A and SAR1B interact with MOG1, and are required for MOG1-mediated cell surface expression and function of Nav1.5. PMID: 30251687
    2. Targeted next generation DNA sequencing revealed several rare heterozygous missense variants in both MTTP and APOB genes known or predicted to be deleterious, in addition to a novel heterozygous missense variant in SAR1B, which encodes the gene causing chylomicron retention disease PMID: 29540175
    3. Report compensatory Sar1a elevation after Sar1b gene deletion in Caco-2/15 cells prevents chylomicron collapse. PMID: 28982670
    4. SAR1B polymorphisms were associated with Alzheimer's disease (AD) risk; results were not significant after correction for multiple tests. Simultaneous screening using SAR1B rs11948613 and ApoE epsilon4 status offered a better sensitivity for AD screening. PMID: 25703997
    5. Our data also suggest that Sar1B overexpression contributes to regulation of CHOL transport and metabolism by facilitating rapid uptake and transport of CHOL. PMID: 25826777
    6. although Sar1A antagonizes the lipoprotein secretion-promoting activity of Sar1B, both isoforms modulate the expression of genes encoding cholesterol biosynthetic enzymes and the synthesis of cholesterol de novo. PMID: 24338480
    7. the behavior of the human of Sar1A and Sar1B, a key component of the COPII family of vesicle coat proteins, was examined. PMID: 22974979
    8. Sar1b expression may promote intestinal lipid transport with the involvement of the coat protein complex II network and the processing of SREBP-1c. PMID: 21836065
    9. Variable phenotypic expression of chylomicron retention disease in a kindred carrying a mutation of the Sara2 gene. PMID: 19846172
    10. identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption PMID: 12692552
    11. Sara2 is an important gene in processes involving erythroid cell proliferation and differentiation. PMID: 15943909
    12. Five mutations in the SAR1B gene causing Anderson disease. PMID: 17945526
    13. muscular as well as cardiac abnormalities that could be related to the reported expression of SARA2 in these tissues PMID: 18786134

    顯示更多

    收起更多

  • 相關疾病：
    Chylomicron retention disease (CMRD)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
  • 蛋白家族：
    Small GTPase superfamily, SAR1 family
  • 組織特異性：
    Expressed in many tissues including small intestine, liver, muscle and brain.
  • 數據庫鏈接：

    HGNC: 10535

    OMIM: 246700

    KEGG: hsa:51128

    STRING: 9606.ENSP00000385432

    UniGene: Hs.432984



主站蜘蛛池模板： 亚洲最大的熟女水蜜桃av网站| 亚洲国产成人第一天堂| 麻豆妓女爽爽一区二区三| 波多野结衣初尝黑人| 99精品视频九九精品视频| 老牛精品亚洲成av人片| 国产7色在线 | 国产| 亚洲日本中文字幕乱码在线| 亚洲精品区午夜亚洲精品区| 日本高清视频在线www色| 一区二区乱子伦在线播放| 男ji大巴进入女人的视频小说| 亚洲和欧洲一码二码区别7777| 久久性色欲av免费精品观看| 人妻熟妇乱又伦精品视频无广告| 男女下面一进一出无遮挡 | 亚洲 制服 丝袜 无码 在线| 亚洲精品久久| 少妇高潮喷潮久久久影院| 亚洲精品一区二区不卡| 一本无码中文字幕在线观| 成人奭片免费观看| 亚洲v欧美v国产v在线观看| 欧美人与动欧交视频| 五月婷婷激情第四季| 日本高清无卡码一区二区| 亚洲a无码综合a国产av中文| 国产偷亚洲偷欧美偷精品| 国产精品国产三级国产a| 伊人久久大香线蕉av综合| 男女免费观看在线爽爽爽视频| 一本色道久久综合亚洲精品| √天堂资源地址在线官网| 成人做爰视频www网站| 国产成_人_综合_亚洲_国产| 无码h黄肉3d动漫在线观看| 欧美精品中文字幕亚洲专区| 2018年秋霞无码片| 亚洲熟妇自偷自拍另类| 国产精品乱码一区二区三区 | 女人和拘做受全程看视频|