在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SAR1B Antibody

SAR1B Antibody

  • 中文名稱：
    SAR1B兔多克隆抗體
  • 貨號：
    CSB-PA020703GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ANDD antibody; CMRD antibody; GTBPB antibody; GTP binding protein SAR1b antibody; GTP binding protein Sara antibody; GTP-binding protein B antibody; GTP-binding protein SAR1B antibody; SAR1 gene homolog B (S. cerevisiae) antibody; SAR1 homolog B antibody; SAR1a gene homolog 2 antibody; SAR1B antibody; SAR1B_HUMAN antibody; SARA2 antibody; SARB antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human SAR1B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex. Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis.
  • 基因功能參考文獻：
    1. Study data suggest that SAR1A and SAR1B are the critical regulators of trafficking of Nav1.5. Moreover, SAR1A and SAR1B interact with MOG1, and are required for MOG1-mediated cell surface expression and function of Nav1.5. PMID: 30251687
    2. Targeted next generation DNA sequencing revealed several rare heterozygous missense variants in both MTTP and APOB genes known or predicted to be deleterious, in addition to a novel heterozygous missense variant in SAR1B, which encodes the gene causing chylomicron retention disease PMID: 29540175
    3. Report compensatory Sar1a elevation after Sar1b gene deletion in Caco-2/15 cells prevents chylomicron collapse. PMID: 28982670
    4. SAR1B polymorphisms were associated with Alzheimer's disease (AD) risk; results were not significant after correction for multiple tests. Simultaneous screening using SAR1B rs11948613 and ApoE epsilon4 status offered a better sensitivity for AD screening. PMID: 25703997
    5. Our data also suggest that Sar1B overexpression contributes to regulation of CHOL transport and metabolism by facilitating rapid uptake and transport of CHOL. PMID: 25826777
    6. although Sar1A antagonizes the lipoprotein secretion-promoting activity of Sar1B, both isoforms modulate the expression of genes encoding cholesterol biosynthetic enzymes and the synthesis of cholesterol de novo. PMID: 24338480
    7. the behavior of the human of Sar1A and Sar1B, a key component of the COPII family of vesicle coat proteins, was examined. PMID: 22974979
    8. Sar1b expression may promote intestinal lipid transport with the involvement of the coat protein complex II network and the processing of SREBP-1c. PMID: 21836065
    9. Variable phenotypic expression of chylomicron retention disease in a kindred carrying a mutation of the Sara2 gene. PMID: 19846172
    10. identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption PMID: 12692552
    11. Sara2 is an important gene in processes involving erythroid cell proliferation and differentiation. PMID: 15943909
    12. Five mutations in the SAR1B gene causing Anderson disease. PMID: 17945526
    13. muscular as well as cardiac abnormalities that could be related to the reported expression of SARA2 in these tissues PMID: 18786134

    顯示更多

    收起更多

  • 相關疾病：
    Chylomicron retention disease (CMRD)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
  • 蛋白家族：
    Small GTPase superfamily, SAR1 family
  • 組織特異性：
    Expressed in many tissues including small intestine, liver, muscle and brain.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10535

    OMIM: 246700

    KEGG: hsa:51128

    STRING: 9606.ENSP00000385432

    UniGene: Hs.432984



主站蜘蛛池模板： 欧美多人片高潮野外做片黑人| 亚洲裸男gv网站| 欧美 变态 另类 人妖| 欧美真人性做爰全过程| 18禁男女爽爽爽午夜网站免费| 亚洲日韩av无码中文字幕美国| 97久久国产露脸精品国产| 免费无码成人av在线播放不卡| 日本高清一区二区三| 亚洲欧美国产精品久久久久久久| 日本三级吃奶头添泬| 大屁股熟女白浆一区二区| 国内少妇高潮嗷嗷叫在线播放| 久久精品国产一区二区三区不卡 | 国产精品va在线观看无码| 亚洲综合色噜噜狠狠网站超清| 日韩高清在线观看永久| 搡老熟女国产| 久久无码专区国产精品s| 成年女人免费v片| 久久久精品2019免费观看| 亚洲欧洲中文日韩乱码av| 亚洲成av人片在线观看天堂无码| 国产 麻豆 日韩 欧美 久久| 巨大乳做爰视频在线看| 很黄很黄的曰批视频| 色偷偷亚洲男人本色| 欧美成人免费全部| 奇米影视7777狠狠狠狠色| 国产欧美日韩精品丝袜高跟鞋| 成人h动漫精品一区二区无码| 日韩国产丝袜人妻一二区| 国模国产精品嫩模大尺度视频| 久久久久人妻一区精品果冻| 亚洲精品久久久久久久久久久| 亚洲一卡2卡3卡4卡 精品| 国产一区精选播放022| а√在线中文网新版地址在线| 男人扒开添女人下部免费视频| 亚拍精品一区二区三区探花| 99精品视频在线观看免费蜜桃|