在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RRP8 Antibody

RRP8 Antibody

  • 中文名稱：
    RRP8兔多克隆抗體
  • 貨號(hào)：
    CSB-PA008360
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of MCF-7 cells using Cerebral 1 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RRP8
  • 別名：
    Cerebral protein 1 antibody; hypothetical protein LOC23378 antibody; KIAA0409 antibody; NML antibody; Nucleomethylin antibody; Ribosomal RNA processing 8 methyltransferase homolog antibody; Ribosomal RNA processing 8, methyltransferase, homolog (yeast) antibody; Ribosomal RNA processing protein 8 antibody; Ribosomal RNA-processing protein 8 antibody; RRP 8 antibody; RRP8 antibody; RRP8 methyltransferase homolog antibody; RRP8_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Cerebral 1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
  • 基因功能參考文獻(xiàn)：
    1. NML depletion increases 60S ribosomal protein L11 (RPL11) levels in the ribosome-free fraction and protein levels of p53 through an RPL11-MDM2 complex, which activates the p53 pathway. PMID: 27149924
    2. Breast tumors without detectable nucleolar NML expression had poor survival. PMID: 26505814
    3. Among Systemic lupus erythematosus patients, 63.6% and 45.5% of those with lupus nephritis were positive for anti-RRP8 and anti-TNP1 antibodies, compared with 12.5% and 9.4% of Systemic lupus erythematosus patients without nephritis, respectively. PMID: 26098692
    4. Data indicate that the the nucleomethylin (NML)-SirT1 interaction was competitively inhibited by rRNA. PMID: 23897426
    5. These observations suggest that NML may regulate consumption of hepatic triglyceride in liver regeneration after partial hepatectomy due to storage of excess ATP. PMID: 19819226

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus, nucleolus. Note=Localizes at rDNA locus.
  • 蛋白家族：
    Methyltransferase superfamily, RRP8 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29030

    OMIM: 615818

    KEGG: hsa:23378

    STRING: 9606.ENSP00000254605

    UniGene: Hs.652255



主站蜘蛛池模板： 国内少妇毛片视频| 免费无码午夜理论电影| 亚洲精品久久久久中文字幕 | 国产成人免费ā片在线观看老同学| 岛国4k人妻一区二区三区| 国产成人久久av免费看| 亚洲国产区男人本色| 国产性生交xxxxx免费| 国产成人亚洲综合网色欲网| 亚洲sm另类一区二区三区| 色妺妺视频网| 国产高潮国产高潮久久久| 一区三区不卡高清影视| 在线播放免费播放av片| 国产大片黄在线观看| 3d动漫精品一区二区三区 | 日欧一片内射va在线影院| 99久久国产宗和精品1上映| 久久中文字幕乱码久久午夜| 青草国产精品久久久久久| 欧美与黑人午夜性猛交久久久 | 亚洲精品久久一区二区无卡| 性做久久久久久久免费看| 日本免费一区二区三区最新| 国产欧美另类久久久精品图片| 亚洲国产成人综合在线不卡| 四虎国产精品永久在线观看| 久久国产avjust麻豆| 欧美国产伦久久久久久久| 加勒比东京热无码一区| 色噜噜狠狠一区二区三区| 国产真实伦在线观看视频| 再深点灬舒服灬太大了在线视频| 亚欧免费无码aⅴ在线观看 | 97se亚洲国产综合自在线尤物| 亚洲日本va中文字幕人妖| 狠狠噜天天噜日日噜| 玩弄人妻少妇500系列视频| 一本大道无码av天堂| 人妻少妇精品无码专区app| 老子午夜精品无码|