在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RPS27A Antibody

RPS27A Antibody

  • 中文名稱：
    RPS27A兔多克隆抗體
  • 貨號：
    CSB-PA01639A0Rb
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA01639A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RPS27A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RPS27A
  • 別名：
    RPS27A antibody; UBA80 antibody; UBCEP1 antibody; Ubiquitin-40S ribosomal protein S27a antibody; Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a antibody; Small ribosomal subunit protein eS31)] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-40S ribosomal protein S27a protein (16-56AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，RPS27A Antibody (CSB-PA01639A0Rb)，的標記方式是Non-conjugated。對于RPS27A Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA01639B0Rb RPS27A Antibody, HRP conjugated ELISA
    FITC CSB-PA01639C0Rb RPS27A Antibody, FITC conjugated
    Biotin CSB-PA01639D0Rb RPS27A Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.; Component of the 40S subunit of the ribosome.
  • 基因功能參考文獻：
    1. this study shows that interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line PMID: 28913776
    2. the full-length cDNA sequence of MMSA-8 was cloned in MM and it was hypothesized that MMSA-8 is MM-associated RPS27A transcript variant 1 PMID: 28498418
    3. RPS27a enhances viral LMP1-mediated proliferation and invasion, suggesting that RPS27a interacts with LMP1 and stabilizes it by suppressing proteasome-mediated ubiquitination. PMID: 28735865
    4. Imatinib-resistant K562/G01 cells expressed significantly higher levels of STAT3 and RPS27a compared with those of K562 cells. PMID: 26942564
    5. RPS27A expression was found to have a weak inverse correlation with overexpression of multifunctional protein YB-1 in HCC tissues. PMID: 24833360
    6. RPS27a appears to be a novel stress sensor in the cell which amplifies p53 response to arrest cell cycle. PMID: 25592822
    7. Knockdown of RPS27a inhibits the proliferation, induces cell cycle arrest and potentiates the effect of imatinib on apoptosis of K562 cells. PMID: 24680683
    8. Gene expression profiles showed that RPS27A was down-regulated in epidermolysis bullosa subtypes. PMID: 22716248
    9. S27a plays a non-redundant role in mediating p53 activation in response to ribosomal stress via interplaying with MDM2. PMID: 21561866
    10. ubiquitin carboxyl extension protein 1 is overexpressed in prostate cancer PMID: 15647830

    顯示更多

    收起更多

  • 亞細胞定位：
    [Ubiquitin]: Cytoplasm. Nucleus.
  • 蛋白家族：
    Ubiquitin family; Eukaryotic ribosomal protein eS31 family
  • 數據庫鏈接：

    HGNC: 10417

    OMIM: 191343

    KEGG: hsa:6233

    STRING: 9606.ENSP00000272317

    UniGene: Hs.311640



主站蜘蛛池模板： 国产成人一区二区三区在线观看| 免费观看亚洲人成网站| 又紧又大又爽精品一区二区| 正在播放东北夫妻内射| 精品国产一区二区三区四区精华液| 久久婷婷色综合老司机| 成人午夜福利视频后入| 玩弄少妇人妻| 国产天堂久久天堂av色综合| av激情亚洲男人的天堂| av天堂亚洲区无码先锋影音| 亚洲精品夜夜夜| 亚洲日本中文字幕天天更新 | 色欲av巨乳无码一区二区| 国产高清av喷水白丝护士| 欧美婷婷六月丁香综合色| 午夜成人亚洲理伦片在线观看| 高清情侣国语自产拍| 亚洲精品入口一区二区乱麻豆精品 | 亚洲一区二区三区写真| 正在播放的国产a一片| 麻豆精品偷拍人妻在线网址 | 欧美最猛黑人xxxx黑人猛交| 欧美精品黑人粗大破除| 成人免费毛片内射美女-百度| 国产av成人一区二区三区| 亚洲热无码av一区二区东京热av | 无码毛片视频一区二区本码| 长腿校花无力呻吟娇喘| 日本免费一区二区三区日本| 免费无码黄十八禁网站在线观看 | 成人午夜精品无码区久久| 狠狠色丁香久久婷婷综合五月 | 精品无码成人网站久久久久久| 强行糟蹋人妻hd中文| 特级做a爰片毛片免费看108| 特黄做受又大又粗又长大片| 性色香蕉av久久久天天网| 男女裸体影院高潮| 正在播放重口老熟女露脸| 在线观看国产日韩亚洲中|