在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RPS27A Antibody, HRP conjugated

RPS27A Antibody, HRP conjugated

  • 中文名稱：
    RPS27A兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA01639B0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RPS27A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RPS27A
  • 別名：
    RPS27A antibody; UBA80 antibody; UBCEP1 antibody; Ubiquitin-40S ribosomal protein S27a antibody; Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a antibody; Small ribosomal subunit protein eS31)] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-40S ribosomal protein S27a protein (16-56AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.; Component of the 40S subunit of the ribosome.
  • 基因功能參考文獻：
    1. this study shows that interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line PMID: 28913776
    2. the full-length cDNA sequence of MMSA-8 was cloned in MM and it was hypothesized that MMSA-8 is MM-associated RPS27A transcript variant 1 PMID: 28498418
    3. RPS27a enhances viral LMP1-mediated proliferation and invasion, suggesting that RPS27a interacts with LMP1 and stabilizes it by suppressing proteasome-mediated ubiquitination. PMID: 28735865
    4. Imatinib-resistant K562/G01 cells expressed significantly higher levels of STAT3 and RPS27a compared with those of K562 cells. PMID: 26942564
    5. RPS27A expression was found to have a weak inverse correlation with overexpression of multifunctional protein YB-1 in HCC tissues. PMID: 24833360
    6. RPS27a appears to be a novel stress sensor in the cell which amplifies p53 response to arrest cell cycle. PMID: 25592822
    7. Knockdown of RPS27a inhibits the proliferation, induces cell cycle arrest and potentiates the effect of imatinib on apoptosis of K562 cells. PMID: 24680683
    8. Gene expression profiles showed that RPS27A was down-regulated in epidermolysis bullosa subtypes. PMID: 22716248
    9. S27a plays a non-redundant role in mediating p53 activation in response to ribosomal stress via interplaying with MDM2. PMID: 21561866
    10. ubiquitin carboxyl extension protein 1 is overexpressed in prostate cancer PMID: 15647830

    顯示更多

    收起更多

  • 亞細胞定位：
    [Ubiquitin]: Cytoplasm. Nucleus.
  • 蛋白家族：
    Ubiquitin family; Eukaryotic ribosomal protein eS31 family
  • 數據庫鏈接：

    HGNC: 10417

    OMIM: 191343

    KEGG: hsa:6233

    STRING: 9606.ENSP00000272317

    UniGene: Hs.311640



主站蜘蛛池模板： 日韩免费无砖专区2020狼| 天堂aⅴ无码一区二区三区| 成人做爰100部片免费下载| 日本人又黄又爽又色的视频| 国产成人午夜福利电影在线播放| 丰满妇女强制高潮18xxxx| 国产免费又爽又色又粗视频| 欧美人与禽猛交狂配| 又黄又硬又湿又刺激视频免费| 亚洲爆乳成av人在线视水卜| 亚洲国产精品一区二区www| 国产精品久久久久久久久动漫 | 娇妻玩4p被三个男人伺候电影| 国产丰满老熟女重口对白| 中文字幕婷婷日韩欧美亚洲| 免费不卡无码av在线观看| 国精产品一区一区三区免费视频 | 99精品国产一区二区三区| 久久国产成人免费网站777| 女人摸下面自熨视频在线播放 | 中文无码乱人伦中文视频在线v| 日韩乱码人妻无码中文字幕| 国产粉嫩嫩00在线正在播放| 亚洲国产成人久久一区| 内射少妇一区27p| 久久久久久国产精品免费免费男同| 99久久国产露脸精品| 在线观看国产精品av| 少妇放荡的呻吟干柴烈火免费视频| 国产98在线 | 日韩| 国产99久久亚洲综合精品西瓜tv| 美女又大又黄www免费网站| 小鲜肉自慰网站| 国产精品久久久久久无码| 欧美乱大交av片久久123| 欧美性猛少妇xxxxx免费| 日本熟妇人妻xxxx| 青青草国产精品日韩欧美| 久久亚洲人成电影网| 老熟妇乱子伦牲交视频| 国产网友自拍在线视频|