在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RPS27A Antibody, FITC conjugated

RPS27A Antibody, FITC conjugated

  • 中文名稱：
    RPS27A兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA01639C0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RPS27A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RPS27A
  • 別名：
    RPS27A antibody; UBA80 antibody; UBCEP1 antibody; Ubiquitin-40S ribosomal protein S27a antibody; Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a antibody; Small ribosomal subunit protein eS31)] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-40S ribosomal protein S27a protein (16-56AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.; Component of the 40S subunit of the ribosome.
  • 基因功能參考文獻：
    1. this study shows that interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line PMID: 28913776
    2. the full-length cDNA sequence of MMSA-8 was cloned in MM and it was hypothesized that MMSA-8 is MM-associated RPS27A transcript variant 1 PMID: 28498418
    3. RPS27a enhances viral LMP1-mediated proliferation and invasion, suggesting that RPS27a interacts with LMP1 and stabilizes it by suppressing proteasome-mediated ubiquitination. PMID: 28735865
    4. Imatinib-resistant K562/G01 cells expressed significantly higher levels of STAT3 and RPS27a compared with those of K562 cells. PMID: 26942564
    5. RPS27A expression was found to have a weak inverse correlation with overexpression of multifunctional protein YB-1 in HCC tissues. PMID: 24833360
    6. RPS27a appears to be a novel stress sensor in the cell which amplifies p53 response to arrest cell cycle. PMID: 25592822
    7. Knockdown of RPS27a inhibits the proliferation, induces cell cycle arrest and potentiates the effect of imatinib on apoptosis of K562 cells. PMID: 24680683
    8. Gene expression profiles showed that RPS27A was down-regulated in epidermolysis bullosa subtypes. PMID: 22716248
    9. S27a plays a non-redundant role in mediating p53 activation in response to ribosomal stress via interplaying with MDM2. PMID: 21561866
    10. ubiquitin carboxyl extension protein 1 is overexpressed in prostate cancer PMID: 15647830

    顯示更多

    收起更多

  • 亞細胞定位：
    [Ubiquitin]: Cytoplasm. Nucleus.
  • 蛋白家族：
    Ubiquitin family; Eukaryotic ribosomal protein eS31 family
  • 數據庫鏈接：

    HGNC: 10417

    OMIM: 191343

    KEGG: hsa:6233

    STRING: 9606.ENSP00000272317

    UniGene: Hs.311640



主站蜘蛛池模板： 日本三级手机在线播放线观看| 国产精品亚洲аv久久| 在教室伦流澡到高潮hgl视频| 加勒比无码一区二区三区| 日韩丰满少妇无吗视频激情内射| 国产精品亚洲а∨天堂网 | 小污女导航福利入口| 亚洲一区二区三区四区五区六 | 怡红院免费的全部视频| 麻豆国产人妻欲求不满| 亚洲国产欧美日韩在线人成| 黄a大片av永久免费| 色五月丁香五月综合五月4438| 精品日产卡一卡二卡麻豆| 无码a∨高潮抽搐流白浆| 亚洲愉拍99热成人精品热久久| 97se亚洲精品一区| 狂野av人人澡人人添| 日本在线a一区视频高清视频| 精品人妻无码区二区三区| 欧美亚洲日韩国产人成在线播放 | 亚洲区小说区激情区图片区| 少妇精品揄拍高潮少妇| 欧美综合自拍亚洲综合图| 精品国产免费一区二区三区 | 久久精品青草社区| 久久国产精品成人影院| 婷婷久久久亚洲欧洲日产国码av| 亚洲欧美日韩综合久久久久久| 996热re视频精品视频这里| 国产午夜精品理论片| 末发育娇小性色xxxxx| 国色天香社区视频| 色多多性虎精品无码av| 精品香蕉久久久午夜福利| 国产精品卡一卡2卡3卡4| 国色天香中文字幕在线视频| 欧美日韩国产精品自在自线| 亚洲精品国产精品乱码不99| 久久精品无码专区免费青青| 亚洲精品久久久久一区二区三区 |