在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RMDN3 Antibody, HRP conjugated

  • 中文名稱:
    RMDN3兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA836307LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RMDN3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RMDN3
  • 別名:
    RMDN3 antibody; FAM82A2 antibody; FAM82C antibody; PTPIP51 antibody; hucep-10 antibody; UNQ3122/PRO10274 antibody; Regulator of microtubule dynamics protein 3 antibody; RMD-3 antibody; hRMD-3 antibody; Cerebral protein 10 antibody; Protein FAM82A2 antibody; Protein FAM82C antibody; Protein tyrosine phosphatase-interacting protein 51 antibody; TCPTP-interacting protein 51 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Regulator of microtubule dynamics protein 3 protein (1-470AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
  • 基因功能參考文獻:
    1. Study shows that the VAPB-PTPIP51 tethers regulate autophagy and demonstrates that overexpression of VAPB or PTPIP51 to tighten endoplasmic reticulum-mitochondria contacts impairs, whereas small interfering RNA-mediated loss of VAPB or PTPIP51 to loosen contacts stimulates, autophagosome formation. PMID: 28132811
    2. the latest findings concerning PTPIP51 protein function, regulation and protein complex formation with regard to the involved signaling pathways and subcellular compartments (review) PMID: 27734150
    3. High PTPIP51 expression is associated with glioblastoma. PMID: 25862004
    4. PTPIP51 is regulated by its phosphorylation status combined with a thereby induced subcellular redistribution. PMID: 24501773
    5. The presented data confirms a tyrosine phosphorylation-dependent interaction of PTPIP51 with 14-3-3beta and Raf-1 in vivo and a tyrosine-dependent interaction profile with DAGKalpha and PKA. PMID: 22544307
    6. In glioblastoma PTPIP51 expression increases with the grade of malignancy and PTPIP51 interacts in situ with 14-3-3ss and PTP1B. PMID: 21972092
    7. PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia. PMID: 21513978
    8. PTPIP51 expression was restricted to myeloid precursor cells undergoing differentiation. In blood cells therefore, PTPIP51 expression is restricted to differentiating and mature neutrophil granulocytes. PMID: 20627780
    9. PTPIP51 might be involved in the regulation of cellular processes associated with differentiation, movement, or cytoskeletal organization PMID: 15609043
    10. PTPIP51 is a mitochondrial protein with apoptosis-inducing function and that the N-terminal TM domain is required for both the correct targeting of the protein to mitochondria and its apoptotic functions. PMID: 16820967
    11. PTPIP51 and PTP1B, play a role in differentiation and apoptosis of the cytotrophoblast and syncytiotrophoblast, respectively. Moreover, PTPIP51 may also serve as a cellular signaling partner in angiogenesis and vascular remodeling. PMID: 18854601
    12. FAM82A2 is expressed in keratinocyte carcinoma and their surrounding stroma. PMID: 19012732
    13. The results clearly point toward a strong association between PTPIP51 expression and differentiation in human muscle cells. PMID: 19124842
    14. The promoter methylation status of PTPIP51 seems to influence the expression of PTPIP51, which was seen as elevated in the prostate carcinoma. PMID: 19691131

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族:
    RMDN family
  • 組織特異性:
    Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high
  • 數據庫鏈接:

    HGNC: 25550

    OMIM: 611873

    KEGG: hsa:55177

    STRING: 9606.ENSP00000260385

    UniGene: Hs.511067



主站蜘蛛池模板: 国产影片中文字幕| 亚洲熟女综合一区二区三区| 777精品出轨人妻国产| 国产麻豆精品传媒av国产婷婷| 亚洲精品成人老司机影视| 免费国产成人午夜福利电影| 人人妻人人爽人人添夜夜欢视频| 男女啪啪高清无遮挡免费| 天天摸夜夜添夜夜无码| 久久青草费线频观看| 人妻少妇偷人精品无码| 国产69精品久久久久久妇女迅雷| 国产在线不卡人成视频| 中文无码日韩欧av影视| 亚洲午夜无码久久| 人妻无码久久精品人妻| 1000部精品久久久久久久久| 国产美女午夜福利视频| 又色又爽又黄还免费毛片96下载| 亚洲午夜福利在线视频| 久久久久国产精品无码免费看| 国产一区二区在线视频| 亚洲日韩欧洲无码av夜夜摸| 国产xxx视频在线观看软件| 久青草国产在视频在线观看| 在线精品国产一区二区三区| 国产免费看插插插视频| 大学生久久香蕉国产线看观看| 国产在线拍揄自揄视频网试看| 国产精品卡一卡2卡3卡4| 色中色成人导航| 亚洲第一女人av| 天天天天做夜夜夜夜做无码| 国产精品亚洲综合色区| 五月天精品视频在线观看| 天天做天天摸天天爽天天爱| 狂野欧美性猛xxxx乱大交 | 亚洲欧洲日本综合aⅴ在线| 性生交大片免费看女人按摩| 日日碰狠狠躁久久躁2023| 欧美人与动牲交免费观看网|