在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RMDN3 Antibody, Biotin conjugated

RMDN3 Antibody, Biotin conjugated

  • 中文名稱：
    RMDN3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA836307LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RMDN3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RMDN3
  • 別名：
    RMDN3 antibody; FAM82A2 antibody; FAM82C antibody; PTPIP51 antibody; hucep-10 antibody; UNQ3122/PRO10274 antibody; Regulator of microtubule dynamics protein 3 antibody; RMD-3 antibody; hRMD-3 antibody; Cerebral protein 10 antibody; Protein FAM82A2 antibody; Protein FAM82C antibody; Protein tyrosine phosphatase-interacting protein 51 antibody; TCPTP-interacting protein 51 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Regulator of microtubule dynamics protein 3 protein (1-470AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
  • 基因功能參考文獻：
    1. Study shows that the VAPB-PTPIP51 tethers regulate autophagy and demonstrates that overexpression of VAPB or PTPIP51 to tighten endoplasmic reticulum-mitochondria contacts impairs, whereas small interfering RNA-mediated loss of VAPB or PTPIP51 to loosen contacts stimulates, autophagosome formation. PMID: 28132811
    2. the latest findings concerning PTPIP51 protein function, regulation and protein complex formation with regard to the involved signaling pathways and subcellular compartments (review) PMID: 27734150
    3. High PTPIP51 expression is associated with glioblastoma. PMID: 25862004
    4. PTPIP51 is regulated by its phosphorylation status combined with a thereby induced subcellular redistribution. PMID: 24501773
    5. The presented data confirms a tyrosine phosphorylation-dependent interaction of PTPIP51 with 14-3-3beta and Raf-1 in vivo and a tyrosine-dependent interaction profile with DAGKalpha and PKA. PMID: 22544307
    6. In glioblastoma PTPIP51 expression increases with the grade of malignancy and PTPIP51 interacts in situ with 14-3-3ss and PTP1B. PMID: 21972092
    7. PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia. PMID: 21513978
    8. PTPIP51 expression was restricted to myeloid precursor cells undergoing differentiation. In blood cells therefore, PTPIP51 expression is restricted to differentiating and mature neutrophil granulocytes. PMID: 20627780
    9. PTPIP51 might be involved in the regulation of cellular processes associated with differentiation, movement, or cytoskeletal organization PMID: 15609043
    10. PTPIP51 is a mitochondrial protein with apoptosis-inducing function and that the N-terminal TM domain is required for both the correct targeting of the protein to mitochondria and its apoptotic functions. PMID: 16820967
    11. PTPIP51 and PTP1B, play a role in differentiation and apoptosis of the cytotrophoblast and syncytiotrophoblast, respectively. Moreover, PTPIP51 may also serve as a cellular signaling partner in angiogenesis and vascular remodeling. PMID: 18854601
    12. FAM82A2 is expressed in keratinocyte carcinoma and their surrounding stroma. PMID: 19012732
    13. The results clearly point toward a strong association between PTPIP51 expression and differentiation in human muscle cells. PMID: 19124842
    14. The promoter methylation status of PTPIP51 seems to influence the expression of PTPIP51, which was seen as elevated in the prostate carcinoma. PMID: 19691131

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    RMDN family
  • 組織特異性：
    Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25550

    OMIM: 611873

    KEGG: hsa:55177

    STRING: 9606.ENSP00000260385

    UniGene: Hs.511067



主站蜘蛛池模板： 亚洲人成电影在线天堂色| 国产成人精品视频ⅴa片软件竹菊| 国产一精品一av一免费| 国产伦精品一区二区三区免费迷| 男人女人午夜视频免费| 精品少妇人妻av久久久| 中国肥老太婆高清video| 午夜爽爽爽男女免费观看麻豆国产| 狠狠色噜噜狠狠狠狠五月婷| 亚洲 小说 欧美 激情 另类| 国产精品久久久亚洲| 久久久久欧美国产高潮| 免费无码av片在线观看网址| 在线观看无码av网址| 精品亚洲麻豆1区2区3区| 131美女爱做视频| 天天天天做夜夜夜夜做无码| 午夜内射中出视频| 国产又色又爽又刺激在线观看| 国产精品沙发午睡系列| 娇妻被黑人粗大高潮白浆| 久久精品国产亚洲欧美| 亚洲高清国产拍精品26u| 精品香蕉99久久久久网站| 搡老熟女老女人一区二区| 国产精品无码av无码| 少妇扒开双腿让我看个够| 无遮挡十八禁污污污网站| 麻豆一区二区三区蜜桃免费| 国产又猛又黄又爽| 精品国产av最大网站| 永久黄网站色视频免费看| 国内精品视频一区二区三区| 国产成人精品一区二区3| 国产色欲色欱www在线| 国产精品久久久久久av福利| 精品人伦一区二区三电影| 国产妇女馒头高清泬20p多毛 | 大帝av在线一区二区三区| 2020国产激情视频在线观看| 无码aⅴ精品一区二区三区|