在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RIT2 Antibody, FITC conjugated

  • 中文名稱:
    RIT2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA860769LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RIT2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RIT2
  • 別名:
    GTP binding protein Rit2 antibody; GTP binding protein Roc2 antibody; GTP-binding protein Rit2 antibody; Ras like protein expressed in neurons antibody; Ras like without CAAX 2 antibody; Ras like without CAAX protein 2 antibody; Ras-like protein expressed in neurons antibody; Ras-like without CAAX protein 2 antibody; RIBA antibody; Ric (Drosophila) like antibody; Ric like antibody; Ric like, expressed in neurons antibody; RIN antibody; RIT2 antibody; RIT2_HUMAN antibody; ROC2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human GTP-binding protein Rit2 protein (1-150AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
  • 基因功能參考文獻:
    1. RIT2 gene was recently introduced as a susceptibility gene in neurological disorders, a group of major problems in human society affecting millions of people worldwide. Several variants, including single nucleotide polymorphisms and CNVs, have been identified and studied in different populations. PMID: 29860660
    2. Significant association of RIT2 Polymorphisms was observed between rs12456492 and two disorders, Parkinson's disease and essential tremor PMID: 26941103
    3. An RIT2 gene variant was found to be a risk factor for autism spectrum disorder in Iranian patients. PMID: 28190241
    4. Findings indicate for the first time, selective advantage for a human-specific allele at an short tandem repeat locus in the human RIT2 core promoter. PMID: 28214997
    5. RIT2 rs12456492 do not increase the risk of developing Parkinson's in Han Chinese. PMID: 27889863
    6. The current meta-analysis suggested that rs12456492 might be associated with increased PD risk in Asian populations, but studies using larger sample sizes and different ethnic populations will be needed to further confirm this association. PMID: 26334395
    7. findings increase the likelihood of association between Parkinson's disease and RIT2 variant in Asian populations PMID: 25146456
    8. performed a case-control replication study in this population and investigated RIT2 rs12456492 variant in a large cohort of Chinese Han individuals PMID: 25559334
    9. Its polymorphism is associated with Parkinson's disease in a Han Chinese population. PMID: 25457028
    10. The data of this study suggested that the RIT2 polymorphisms are associated with Parkinson disease etiology. PMID: 25534083
    11. the G allele, GG and GA genotype of rs12456492(A/G) polymorphism may increase the risk of Parkinson disease. [meta-analysis] PMID: 26188085
    12. failed to replicate the RIT2 rs12456492 variant as a genetic risk factor for Parkinson's disease in our population. PMID: 23635658
    13. These studies confirm the expression of RIT2 in retinal neuronal cells. PMID: 23805044
    14. This meta-analysis identifies a novel Parkinson's disease locus, RIT2, that replicates several previously identified loci on chromosome 18. PMID: 22451204
    15. Rin interacts directly with dopamine transporter DAT in a protein kinase (PK)C-regulated manner and is required for PKC-mediated DAT internalization. PMID: 21957239
    16. Modulates the activation of the Brn-3a regulated egr-1 promoter by the N-terminal domain of Brn-3a PMID: 12934100
    17. Neuron-specific small GTPase Rin is involved in downstream signaling of plexin B3. PMID: 16122393
    18. observations establish Rin as a neuronal specific regulator of neurotrophin signaling, required to couple NGF stimulation to sustain activation of p38 MAP kinase and b-Raf signaling cascades required for neuronal development PMID: 16157584

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cell membrane.
  • 蛋白家族:
    Small GTPase superfamily, Ras family
  • 組織特異性:
    Neuron-specific.
  • 數據庫鏈接:

    HGNC: 10017

    OMIM: 609592

    KEGG: hsa:6014

    STRING: 9606.ENSP00000321805

    UniGene: Hs.464985



主站蜘蛛池模板: 果冻传媒18禁免费视频| 无码中文av有码中文a| 女同免费毛片在线播放| 在线精品亚洲第一区焦香| 啪啪无码人妻丰满熟妇| 亚洲日韩av一区二区三区四区| 99热门精品一区二区三区无码| 日韩人妻不卡一区二区三区| 超薄丝袜足j好爽在线| 亚洲欧美国产精品久久久久久久 | 无码人妻一区二区三区在线| 亚洲色播爱爱爱爱爱爱爱| 精品国产一区二区三区av片| 亚洲精品伊人久久久大香| 国产精品对白刺激久久久| 色橹橹欧美在线观看视频高清| 日本强伦姧人妻一区二区| 一本色道久久综合亚州精品蜜桃| 精品国产成人网站一区在线| 蜜桃久久精品成人无码av| 丰满人妻一区二区三区无码av| 久久久噜噜噜久久熟女色 | 国产精品白丝喷浆| 亚洲 欧美 日韩 综合aⅴ视频| 中国大陆高清aⅴ毛片| 国产99久久亚洲综合精品西瓜tv| 人人爽人人添人人超| 国产欧美日韩精品丝袜高跟鞋| 久久久久久a亚洲欧洲av冫| 亚洲男女羞羞无遮挡久久丫| 18禁无遮挡羞羞污污污污免费| 极品少妇伦理一区二区| 少妇人妻偷人精品视蜜桃| 国产精品99久久免费| 天下第一社区视频www日本| 日本一卡2卡3卡4卡无卡免费网站| 久久精品久久电影免费理论片| 国产成人精品久久一区二区| 国产男小鲜肉同志免费| 国产精品一区二区久久| 国产真实自在自线免费精品|