在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RC3H2 Antibody

  • 中文名稱:
    RC3H2兔多克隆抗體
  • 貨號:
    CSB-PA884510LA01HU
  • 規格:
    ¥440
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RC3H2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RC3H2
  • 別名:
    2900024N03Rik antibody; 9430019J22Rik antibody; D930043C02Rik antibody; FLJ20301 antibody; FLJ20713 antibody; Membrane associated DNA binding protein antibody; Membrane associated nucleic acid binding protein antibody; Membrane-associated nucleic acid-binding protein antibody; MGC52176 antibody; MNAB antibody; OTTHUMP00000022076 antibody; OTTHUMP00000022077 antibody; OTTMUSP00000013545 antibody; OTTMUSP00000013546 antibody; Rc3h2 antibody; RC3H2_HUMAN antibody; Ring finger and CCCH type domains 2 antibody; RING finger and CCCH type zinc finger domain containing protein 2 antibody; Ring finger and CCCH-type zinc finger domain-containing protein 2 antibody; ring finger and CCCH-type zinc finger domains 2 antibody; RING finger protein 164 antibody; RNF164 antibody; roquin-2 antibody; RP23-321B3.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Roquin-2 protein (251-506AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,RC3H2 Antibody (CSB-PA884510LA01HU),的標記方式是Non-conjugated。對于RC3H2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA884510LB01HU RC3H2 Antibody, HRP conjugated ELISA
    FITC CSB-PA884510LC01HU RC3H2 Antibody, FITC conjugated
    Biotin CSB-PA884510LD01HU RC3H2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Post-transcriptional repressor of mRNAs containing a conserved stem loop motif, called constitutive decay element (CDE), which is often located in the 3'-UTR, as in HMGXB3, ICOS, IER3, NFKBID, NFKBIZ, PPP1R10, TNF and in many more mRNAs. Binds to CDE and promotes mRNA deadenylation and degradation. This process does not involve miRNAs. In follicular helper T (Tfh) cells, represses of ICOS and TNFRSF4 expression, thus preventing spontaneous Tfh cell differentiation, germinal center B-cell differentiation in the absence of immunization and autoimmunity. In resting or LPS-stimulated macrophages, controls inflammation by suppressing TNF expression. Also recognizes CDE in its own mRNA and in that of paralogous RC3H1, possibly leading to feedback loop regulation. miRNA-binding protein that regulates microRNA homeostasis. Enhances DICER-mediated processing of pre-MIR146a but reduces mature MIR146a levels through an increase of 3' end uridylation. Both inhibits ICOS mRNA expression and they may act together to exert the suppression. Acts as a ubiquitin E3 ligase. Pairs with E2 enzymes UBE2B, UBE2D2, UBE2E2, UBE2E3, UBE2G2, UBE2K and UBE2Q2 and produces polyubiquitin chains. Shows the strongest activity when paired with UBE2N:UBE2V1 or UBE2N:UBE2V2 E2 complexes and generate both short and long polyubiquitin chains. Involved in the ubiquitination of MAP3K5. Able to interact with double-stranded RNA (dsRNA).
  • 基因功能參考文獻:
    1. Crystal structures, small-angle X-ray scattering, and E2 profiling revealed that while the two paralogs are highly homologous, RC3H2 and RC3H1 are different in their structures and functions. PMID: 26489670
    2. Roquin-1 and roquin-2 proteins function redundantly in mRNA degradation. PMID: 26249698
  • 亞細胞定位:
    Cytoplasm, P-body.
  • 組織特異性:
    Expressed in spleen, testis, ovary and small intestine.
  • 數據庫鏈接:

    HGNC: 21461

    OMIM: 615231

    KEGG: hsa:54542

    STRING: 9606.ENSP00000349783

    UniGene: Hs.533499



主站蜘蛛池模板: 午夜福利理论片在线观看播放| 亚洲va无码专区国产乱码| 亚洲精品一区国产欧美| 国内熟女啪啪自拍| 亚洲国产美国国产综合一区| 国产片av片永久免费观看| 好爽好硬好深高潮视频456| 久久精品www人人爽人人| 忍不住的亲子中文字幕| 极品嫩模高潮叫床| 午夜福利无遮挡十八禁视频| 真人一进一出120秒试看| 久久久久久久综合日本| 国产丰满老熟妇乱xxx1区| 日产电影一区二区三区| 伊人久久成综合久久影院| 亚洲欧洲自拍拍偷精品网 | 日韩精品成人一区二区三区| 试看120分钟做受小视频| 精品国内自产拍在线观看视频| 午夜a理论片在线播放| 色偷偷www.8888在线观看| 国产精品久久久久久不卡盗摄| 国产精品视频永久免费播放| 成人免费看www网址入口| 久草热8精品视频在线观看| av无码av在线a∨天堂毛片| 国产乱人伦中文无无码视频试看| 亚洲不卡中文字幕无码| 亚洲人成网站日本片| 久久久女人与动物群交毛片 | 高清无码一区二区在线观看吞精| 国产欧美日韩综合在线成| 久99久热只有精品国产15| 看免费真人视频网站| 国产a√精品区二区三区四区| 国产成人高清精品免费| 国产成人不卡无码免费视频| 风韵少妇性饥渴推油按摩视频| 亚洲精品电影院| 成人午夜免费无码区|