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  4. RARS2 Antibody

RARS2 Antibody

  • 中文名稱：
    RARS2兔多克隆抗體
  • 貨號：
    CSB-PA732918LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA732918LA01HU diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG labeled by HRP and visualized using 0.05% DAB.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RARS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RARS2
  • 別名：
    Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS), RARS2, RARSL
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Probable arginine--tRNA ligase, mitochondrial protein (230-578aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，RARS2 Antibody (CSB-PA732918LA01HU)，的標記方式是Non-conjugated。對于RARS2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA732918LB01HU RARS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA732918LC01HU RARS2 Antibody, FITC conjugated
    Biotin CSB-PA732918LD01HU RARS2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. Characteristic neuroradiological abnormalities of PCH6 such as vermis and cerebellar hypoplasia and progressive pontocerebellar atrophy may be missing in patients with RARS2 mutations PMID: 27769281
    2. RARS2 gene mutations can cause a metabolic neurodegenerative disease manifesting primarily as early onset epileptic encephalopathies with post-natal microcephaly, without pontocerebellar hypoplasia. PMID: 26970947
    3. Mutations in the RARS2 promoter are likely to represent a new causal mechanism of pontocerebellar hypoplasia. PMID: 25809939
    4. Molecular investigations of RARS2 disclosed the c.25A>G/p.I9V and the c.1586+3A>T in family A. PMID: 22569581
    5. mutations in the gene encoding mitochondrial arginyl-tRNA synthetase, RARS2, may have a role in pontocerebellar hypoplasia type 6 [case report] PMID: 22086604

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    收起更多

  • 相關疾病：
    Pontocerebellar hypoplasia 6 (PCH6)
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 數據庫鏈接：

    HGNC: 21406

    OMIM: 611523

    KEGG: hsa:57038

    STRING: 9606.ENSP00000358549

    UniGene: Hs.485910



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