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  4. RARS2 Antibody

RARS2 Antibody

  • 中文名稱：
    RARS2兔多克隆抗體
  • 貨號：
    CSB-PA732918ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: RARS2 antibody at 2.68 μg/ml
      Lane 1: Mouse kidney tissue
      Lane 2: HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 66 kDa
      Observed band size: 66 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA732918ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA732918ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RARS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RARS2
  • 別名：
    arginine tRNA ligase antibody; arginyl tRNA synthetase 2 mitochondrial antibody; Arginyl tRNA synthetase antibody; Arginyl-tRNA synthetase antibody; ArgRS antibody; DALRD2 antibody; mitochondrial antibody; PCH6 antibody; Probable arginine tRNA ligase antibody; probable arginine tRNA ligase mitochondrial antibody; Probable arginine--tRNA ligase antibody; probable arginyl tRNA synthetase mitochondrial antibody; RARS2 antibody; RARSL antibody; SYRM_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Probable arginine--tRNA ligase, mitochondrial protein (17-340AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. Characteristic neuroradiological abnormalities of PCH6 such as vermis and cerebellar hypoplasia and progressive pontocerebellar atrophy may be missing in patients with RARS2 mutations PMID: 27769281
    2. RARS2 gene mutations can cause a metabolic neurodegenerative disease manifesting primarily as early onset epileptic encephalopathies with post-natal microcephaly, without pontocerebellar hypoplasia. PMID: 26970947
    3. Mutations in the RARS2 promoter are likely to represent a new causal mechanism of pontocerebellar hypoplasia. PMID: 25809939
    4. Molecular investigations of RARS2 disclosed the c.25A>G/p.I9V and the c.1586+3A>T in family A. PMID: 22569581
    5. mutations in the gene encoding mitochondrial arginyl-tRNA synthetase, RARS2, may have a role in pontocerebellar hypoplasia type 6 [case report] PMID: 22086604

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  • 相關疾病：
    Pontocerebellar hypoplasia 6 (PCH6)
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 數據庫鏈接：

    HGNC: 21406

    OMIM: 611523

    KEGG: hsa:57038

    STRING: 9606.ENSP00000358549

    UniGene: Hs.485910



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