在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB17 Antibody

RAB17 Antibody

  • 中文名稱：
    RAB17兔多克隆抗體
  • 貨號：
    CSB-PA863944ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: RAB17 antibody at 3.02μg/ml
      Lane 1: Mouse brain tissue
      Lane 2: Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 24, 10 kDa
      Observed band size: 24 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA863944ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA863944ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RAB17 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RAB17
  • 別名：
    AW413472 antibody; FLJ12538 antibody; OTTHUMP00000164417 antibody; OTTHUMP00000202805 antibody; Rab 17 antibody; Rab17 antibody; RAB17 member RAS oncogene family antibody; RAB17_HUMAN antibody; Ras related protein Rab 17 antibody; Ras related protein Rab17 antibody; Ras-related protein Rab-17 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Ras-related protein Rab-17 protein (1-212AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development. May also play a role in cell migration.
  • 基因功能參考文獻：
    1. Mass spectrometry and immunofluorescence microscopy of efferosomes and phagosomes in macrophages demonstrated that efferosomes lacked the proteins required for antigen presentation and instead recruited the recycling regulator Rab17. PMID: 28005073
    2. Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk MAPK signaling. PMID: 26191189
    3. Rab17 might act as a tumour suppressor gene in hepatocellular carcinoma , and the anti-tumour effects of Rab17 might be partially mediated by the Erk pathway. PMID: 25707355
    4. These results suggest that Rab17 and Rab17-mediated REs are involved in Streptococcus pyogenes-containing autophagosome-like vacuole formation. PMID: 25052408
    5. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
    6. Data reveal new functions for recycling endosomes and Rab17 in pigmentation through a distal step in the process of melanosome release via filopodia. PMID: 21291502

    顯示更多

    收起更多

  • 亞細胞定位：
    Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cell projection, dendrite.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Expressed in melanocytes (at protein level).
  • 數據庫鏈接：

    HGNC: 16523

    OMIM: 602206

    KEGG: hsa:64284

    STRING: 9606.ENSP00000264601

    UniGene: Hs.44278



主站蜘蛛池模板： 精品久久久久久无码不卡| 蜜桃视频在线观看免费网址入口| 中国大陆精品视频xxxx| 久久99精品九九九久久婷婷| 少妇性l交大片欧洲热妇乱xxx| 国产乱人伦偷精品视频| 午夜精品久久久内射近拍高清| 色欲αv一区二区三区天美传媒| 最近2019中文字幕在线| 激情内射亚洲一区二区三区| 摸丰满大乳奶水www免费| 国产日产欧产精品精品推荐免费 | 少妇高潮喷水久久久影院| 日日摸天天碰中文字幕你懂的| 成人a片产无码免费视频在线观看| 亚洲人成欧美中文字幕| 福利cosplayh裸体の福利| 亚洲人成网站观看在线播放| 亚洲中文字幕无码一去台湾| 成人亚洲国产精品一区不卡| 亚洲日韩成人无码| 人人模人人爽人人喊久久| 天堂久久天堂av色综合| 性xxxx欧美老妇506070| 亚洲精品国产精品国自产| 少妇高潮太爽了在线观看| 欧美黑人巨大videos在线| 成人免费午夜无码视频| 好吊妞国产欧美日韩免费观看| 99久久久无码国产精品免费| 亚洲色成人网站永久| 男女高潮喷水在线观看| 小说区 图片区色 综合区| 国产精品18久久久| 国产美熟女乱又伦av果冻传媒| 伊人色合天天久久综合网| 搡8o老女人老妇人老熟| 成人爱做日本视频免费| 色噜噜亚洲男人的天堂www| 草草地址线路①屁屁影院成人| 国产综合色在线视频区|