在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB17 Antibody

RAB17 Antibody

  • 中文名稱：
    RAB17兔多克隆抗體
  • 貨號：
    CSB-PA578011
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA578011(Rab17 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA578011(Rab17 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    RAB17
  • 別名：
    AW413472 antibody; FLJ12538 antibody; OTTHUMP00000164417 antibody; OTTHUMP00000202805 antibody; Rab 17 antibody; Rab17 antibody; RAB17 member RAS oncogene family antibody; RAB17_HUMAN antibody; Ras related protein Rab 17 antibody; Ras related protein Rab17 antibody; Ras-related protein Rab-17 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human Rab17
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development. May also play a role in cell migration.
  • 基因功能參考文獻：
    1. Mass spectrometry and immunofluorescence microscopy of efferosomes and phagosomes in macrophages demonstrated that efferosomes lacked the proteins required for antigen presentation and instead recruited the recycling regulator Rab17. PMID: 28005073
    2. Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk MAPK signaling. PMID: 26191189
    3. Rab17 might act as a tumour suppressor gene in hepatocellular carcinoma , and the anti-tumour effects of Rab17 might be partially mediated by the Erk pathway. PMID: 25707355
    4. These results suggest that Rab17 and Rab17-mediated REs are involved in Streptococcus pyogenes-containing autophagosome-like vacuole formation. PMID: 25052408
    5. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
    6. Data reveal new functions for recycling endosomes and Rab17 in pigmentation through a distal step in the process of melanosome release via filopodia. PMID: 21291502

    顯示更多

    收起更多

  • 亞細胞定位：
    Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cell projection, dendrite.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Expressed in melanocytes (at protein level).
  • 數據庫鏈接：

    HGNC: 16523

    OMIM: 602206

    KEGG: hsa:64284

    STRING: 9606.ENSP00000264601

    UniGene: Hs.44278



主站蜘蛛池模板： 国产乱人伦中文无无码视频试看| 亚洲日本va在线视频观看| 国产在线码观看超清无码视频| 亚洲日韩中文字幕在线不卡最新| 天堂а√在线中文在线最新版| 久久婷婷五月综合色丁香| 国产福利在线视频蜜芽tv| av无码人妻中文字幕| 无码人妻丰满熟妇区96| 久久无码av三级| 久久国产精品萌白酱免费| 亚洲日韩成人无码不卡网站| 欧美va天堂在线电影| 久久综合色鬼综合色| 日本亚洲欧洲另类图片| 欧美人妻少妇精品久久黑人 | 2021年国产精品专区丝袜 | 午夜福利精品亚洲不卡| 又爽又黄又无遮挡的激情视频| 日本精品人妻无码免费大全| 久久精品中文闷骚内射| av蓝导航精品导航| 国产又粗又硬又大爽黄老大爷| 一进一出抽搐gif| 中国女人大白屁股ass| 人妻熟女一区二区aⅴ水野朝阳| 国产成人8x视频网站入口| 在线观看无码不卡av| 丰满日韩放荡少妇无码视频| 香蕉久久人人97超碰caoproen | 国产毛片不卡野外视频| 2019一級特黃色毛片免費看| 男女一边摸一边做爽爽| 亚洲综合精品伊人久久| 99爱在线精品视频免费观看| 国产人妻人伦精品| 一区二区三区中文字幕| 韩国 欧美 日产 国产精品| 内射人妻少妇无码一本一道| 极品少妇hdxx麻豆hdxx| 免费能直接看黄的视频|