在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTOV1 Antibody, HRP conjugated

  • 中文名稱:
    PTOV1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA769809LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTOV1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PTOV1
  • 別名:
    PTOV1 antibody; ACID2 antibody; PP642 antibody; UNQ6127/PRO20092 antibody; Prostate tumor-overexpressed gene 1 protein antibody; PTOV-1 antibody; Activator interaction domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
  • 基因功能參考文獻:
    1. The combination of PTOV1 expression level and HPV status provides more prognostic information compared with HPV status alone in early-stage human laryngeal squamous cell carcinoma. PMID: 26992242
    2. Studies indicate that the number of binding partners and associated cellular functions has increased and helped to identify prostate-tumor-overexpressed-1 (PTOV1) as regulator of gene expression at transcription and translation levels. PMID: 28029646
    3. this study takes the lead to demonstrate that the overexpressed PTOV1 plays a vital role in the tumorigenesis and progression of esophageal squamous cell carcinoma, and it is potentially a valuable prognostic predicator and new chemotherapeutic target for esophageal squamous cell carcinoma PMID: 28651486
    4. All the study samples showed a considerable decrease in PTOV1 expression in prostate cancer and HGPIN compared to morphologically normal glands. PMID: 27804940
    5. High PTOV1 expression was associated with invasive urothelial carcinoma. PMID: 26746655
    6. PTOV1 overexpression is associated with poor survival outcomes of nasopharyngeal carcinoma patients. PMID: 26305455
    7. PTOV1 protein abnormal expression might contribute to the malignant progression of epithelial ovarian cancer. PMID: 25270739
    8. Our study demonstrated that PTOV1 overexpression is correlated with increased aggressiveness of hepatocellular carcinoma and could be a prognostic biomarker for patients with HCC PMID: 25634174
    9. The study showed that PTOV1 is upregulated in breast cancer cell lines and clinical samples, and its expression was positively associated with progression and aggressiveness of breast cancer, suggesting that PTOV1 could serve as an independent prognostic marker. PMID: 24947166
    10. In prostate tumors, the overexpression of PTOV1 was associated with decreased expression of HEY1 and HES1, and this correlation was significant in metastatic lesions. PMID: 24684754
    11. RA-induced cancer cell cytotoxicity was significantly impaired by Zyxin or PTOV1. Overall, our findings suggest that Zyxin and PTOV1 should be considered as critical determinants in cancer therapy with retinoids PMID: 23321499
    12. alpha-Methyl-CoA racemase can be considered a more accurate marker than PTOV1 in the identification of high-grade prostatic intraepithelial neoplasia (HGPIN) and of prostate cancer. PMID: 22507319
    13. PTOV1 expression is associated to more aggressive human carcinomas and more significantly to bladder carcinomas suggesting that this protein is a potential new marker of aggressive disease in the latter tumors. PMID: 21181414
    14. MED25 and PTOV1 differentially modulate retinoic acid sensitivity in cancer cells depending on their expression levels. PMID: 21110951
    15. This protein, overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle. PMID: 12598323
    16. PTOV1 assists flotillin-1 in its translocation to the nucleus and both proteins are required for cell proliferation. PMID: 15713644
    17. PTOV1 is overexpressed in high-grade prostatic intraepithelial neoplasia associated with cancer and is a potential marker for studying the carcinogenesis and progression of prostate cancer. PMID: 18451224

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cell membrane. Cytoplasm, perinuclear region.
  • 蛋白家族:
    Mediator complex subunit 25 family, PTOV1 subfamily
  • 組織特異性:
    Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.
  • 數據庫鏈接:

    HGNC: 9632

    OMIM: 610195

    KEGG: hsa:53635

    STRING: 9606.ENSP00000375717

    UniGene: Hs.587979



主站蜘蛛池模板: 亚洲无日韩码精品| 国产成人亚洲精品| 影音先锋在线亚洲网站| 国产在线第一区二区三区| 18禁免费吃奶摸下激烈视频| 亚洲综合图色40p| 一边摸一边做爽的视频17国产 | 久久久久影院美女国产主播| 久久久久久国产精品免费免费| 国产熟女一区二区三区四区五区| 亚洲精品国产字幕久久不卡| 亚洲乱码日产精品bd在线| 国产在线一区二区香蕉 在线| 国产sm调教视频在线观看| 国产亚洲精品久久久久久小舞 | 久久午夜夜伦鲁鲁片免费无码影视| 中文字幕av伊人av无码av狼人| 日本丶国产丶欧美色综合| 国产98色在线 | 国产| 成人亚洲欧美一区二区三区| 美女扒开腿让男人桶爽app免费看| 99热在线观看| 红桃av一区二区三区在线无码av| 久久精品国产亚洲欧美| 久久国产高潮流白浆免费观看| 国产成人精品亚洲日本在线| 熟妇人妻无码xxx视频| 日日日日做夜夜夜夜做无码| 极品少妇被猛的白浆直喷白浆| 久久人人爽人人爽人人片| 精品久久欧美熟妇www| 精品卡1卡2卡三卡免费网站| 老熟女乱子伦| 无码人妻丰满熟妇啪啪7774| 92国产精品午夜福利无毒不卡| 人妻中出受孕 中文字幕在线| www插插插无码视频网站| 欧美精品黑人粗大| 亚洲裸男gv网站| 午夜精品久久久久久久爽| 国产欧美另类精品久久久|