在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTOV1 Antibody, FITC conjugated

  • 中文名稱:
    PTOV1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA769809LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTOV1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PTOV1
  • 別名:
    PTOV1 antibody; ACID2 antibody; PP642 antibody; UNQ6127/PRO20092 antibody; Prostate tumor-overexpressed gene 1 protein antibody; PTOV-1 antibody; Activator interaction domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
  • 基因功能參考文獻:
    1. The combination of PTOV1 expression level and HPV status provides more prognostic information compared with HPV status alone in early-stage human laryngeal squamous cell carcinoma. PMID: 26992242
    2. Studies indicate that the number of binding partners and associated cellular functions has increased and helped to identify prostate-tumor-overexpressed-1 (PTOV1) as regulator of gene expression at transcription and translation levels. PMID: 28029646
    3. this study takes the lead to demonstrate that the overexpressed PTOV1 plays a vital role in the tumorigenesis and progression of esophageal squamous cell carcinoma, and it is potentially a valuable prognostic predicator and new chemotherapeutic target for esophageal squamous cell carcinoma PMID: 28651486
    4. All the study samples showed a considerable decrease in PTOV1 expression in prostate cancer and HGPIN compared to morphologically normal glands. PMID: 27804940
    5. High PTOV1 expression was associated with invasive urothelial carcinoma. PMID: 26746655
    6. PTOV1 overexpression is associated with poor survival outcomes of nasopharyngeal carcinoma patients. PMID: 26305455
    7. PTOV1 protein abnormal expression might contribute to the malignant progression of epithelial ovarian cancer. PMID: 25270739
    8. Our study demonstrated that PTOV1 overexpression is correlated with increased aggressiveness of hepatocellular carcinoma and could be a prognostic biomarker for patients with HCC PMID: 25634174
    9. The study showed that PTOV1 is upregulated in breast cancer cell lines and clinical samples, and its expression was positively associated with progression and aggressiveness of breast cancer, suggesting that PTOV1 could serve as an independent prognostic marker. PMID: 24947166
    10. In prostate tumors, the overexpression of PTOV1 was associated with decreased expression of HEY1 and HES1, and this correlation was significant in metastatic lesions. PMID: 24684754
    11. RA-induced cancer cell cytotoxicity was significantly impaired by Zyxin or PTOV1. Overall, our findings suggest that Zyxin and PTOV1 should be considered as critical determinants in cancer therapy with retinoids PMID: 23321499
    12. alpha-Methyl-CoA racemase can be considered a more accurate marker than PTOV1 in the identification of high-grade prostatic intraepithelial neoplasia (HGPIN) and of prostate cancer. PMID: 22507319
    13. PTOV1 expression is associated to more aggressive human carcinomas and more significantly to bladder carcinomas suggesting that this protein is a potential new marker of aggressive disease in the latter tumors. PMID: 21181414
    14. MED25 and PTOV1 differentially modulate retinoic acid sensitivity in cancer cells depending on their expression levels. PMID: 21110951
    15. This protein, overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle. PMID: 12598323
    16. PTOV1 assists flotillin-1 in its translocation to the nucleus and both proteins are required for cell proliferation. PMID: 15713644
    17. PTOV1 is overexpressed in high-grade prostatic intraepithelial neoplasia associated with cancer and is a potential marker for studying the carcinogenesis and progression of prostate cancer. PMID: 18451224

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cell membrane. Cytoplasm, perinuclear region.
  • 蛋白家族:
    Mediator complex subunit 25 family, PTOV1 subfamily
  • 組織特異性:
    Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.
  • 數據庫鏈接:

    HGNC: 9632

    OMIM: 610195

    KEGG: hsa:53635

    STRING: 9606.ENSP00000375717

    UniGene: Hs.587979



主站蜘蛛池模板: 国产av人人夜夜澡人人爽麻豆| 国产少妇高潮在线观看| 国产女厕所盗摄老师厕所嘘嘘| 大胸美女被吃奶爽死视频| 搡8o老女人老妇人老熟| 久久精品免视看国产成人明星| a v 在线视频 亚洲免费| 国产成人愉拍精品| 美女视频黄是免费| 亚洲欧洲日产国码在线| 国精品午夜福利视频导航| 欧美精品色婷婷五月综合| 老熟女高潮一区二区三区| 久久国内精品自在自线| 欧美日韩精品成人网站二区| 日本中文字幕乱码免费| 丰满少妇弄高潮了www| 四库影院永久国产精品| 忘忧草社区中文字幕www| 在线亚洲视频网站www色| 欧美精品a∨在线观看| 亚洲小说春色综合另类| 性人久久网av| 男受被做哭激烈娇喘gv视频| 久久精品中文无码资源站| 被技师按摩到高潮的少妇| 一本加勒比hezyo无码专区| 久久99国产精品久久99果冻传媒 | 手机福利视频| 欧美两根一起进3p做受视频| 国产八十老太另类| 拍真实国产伦偷精品| 蜜臀av午夜一区二区三区| 国产第一页浮力影院入口| 亚洲综合激情五月丁香六月| 四虎免费大片aⅴ入口| 国内偷自第一区二区三区| 成人看片黄a免费看| 久久av无码αv高潮αv喷吹| 成人国产三级在线观看| 国产农村乱子伦精品视频|