在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTOV1 Antibody, FITC conjugated

  • 中文名稱:
    PTOV1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA769809LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTOV1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PTOV1
  • 別名:
    PTOV1 antibody; ACID2 antibody; PP642 antibody; UNQ6127/PRO20092 antibody; Prostate tumor-overexpressed gene 1 protein antibody; PTOV-1 antibody; Activator interaction domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Prostate tumor-overexpressed gene 1 protein (2-137AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
  • 基因功能參考文獻:
    1. The combination of PTOV1 expression level and HPV status provides more prognostic information compared with HPV status alone in early-stage human laryngeal squamous cell carcinoma. PMID: 26992242
    2. Studies indicate that the number of binding partners and associated cellular functions has increased and helped to identify prostate-tumor-overexpressed-1 (PTOV1) as regulator of gene expression at transcription and translation levels. PMID: 28029646
    3. this study takes the lead to demonstrate that the overexpressed PTOV1 plays a vital role in the tumorigenesis and progression of esophageal squamous cell carcinoma, and it is potentially a valuable prognostic predicator and new chemotherapeutic target for esophageal squamous cell carcinoma PMID: 28651486
    4. All the study samples showed a considerable decrease in PTOV1 expression in prostate cancer and HGPIN compared to morphologically normal glands. PMID: 27804940
    5. High PTOV1 expression was associated with invasive urothelial carcinoma. PMID: 26746655
    6. PTOV1 overexpression is associated with poor survival outcomes of nasopharyngeal carcinoma patients. PMID: 26305455
    7. PTOV1 protein abnormal expression might contribute to the malignant progression of epithelial ovarian cancer. PMID: 25270739
    8. Our study demonstrated that PTOV1 overexpression is correlated with increased aggressiveness of hepatocellular carcinoma and could be a prognostic biomarker for patients with HCC PMID: 25634174
    9. The study showed that PTOV1 is upregulated in breast cancer cell lines and clinical samples, and its expression was positively associated with progression and aggressiveness of breast cancer, suggesting that PTOV1 could serve as an independent prognostic marker. PMID: 24947166
    10. In prostate tumors, the overexpression of PTOV1 was associated with decreased expression of HEY1 and HES1, and this correlation was significant in metastatic lesions. PMID: 24684754
    11. RA-induced cancer cell cytotoxicity was significantly impaired by Zyxin or PTOV1. Overall, our findings suggest that Zyxin and PTOV1 should be considered as critical determinants in cancer therapy with retinoids PMID: 23321499
    12. alpha-Methyl-CoA racemase can be considered a more accurate marker than PTOV1 in the identification of high-grade prostatic intraepithelial neoplasia (HGPIN) and of prostate cancer. PMID: 22507319
    13. PTOV1 expression is associated to more aggressive human carcinomas and more significantly to bladder carcinomas suggesting that this protein is a potential new marker of aggressive disease in the latter tumors. PMID: 21181414
    14. MED25 and PTOV1 differentially modulate retinoic acid sensitivity in cancer cells depending on their expression levels. PMID: 21110951
    15. This protein, overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle. PMID: 12598323
    16. PTOV1 assists flotillin-1 in its translocation to the nucleus and both proteins are required for cell proliferation. PMID: 15713644
    17. PTOV1 is overexpressed in high-grade prostatic intraepithelial neoplasia associated with cancer and is a potential marker for studying the carcinogenesis and progression of prostate cancer. PMID: 18451224

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cell membrane. Cytoplasm, perinuclear region.
  • 蛋白家族:
    Mediator complex subunit 25 family, PTOV1 subfamily
  • 組織特異性:
    Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.
  • 數據庫鏈接:

    HGNC: 9632

    OMIM: 610195

    KEGG: hsa:53635

    STRING: 9606.ENSP00000375717

    UniGene: Hs.587979



主站蜘蛛池模板: 无码av一区二区三区无码| 97熟女毛毛多熟妇人妻aⅴ| 少妇大叫太大太爽受不了| 国产免费永久精品无码| 国产热re99久久6国产精品首页 | 精品成在人线av无码免费看| 国产96在线 | 欧美| 亚洲国产最大av| 人妻中出无码一区二区三区| 日日摸日日碰夜夜爽av| 国产精品美女久久久久久久| 日本边添边摸边做边爱喷水| 亚洲精品四区麻豆文化传媒| 国产女人乱人伦精品一区二区| 国产精品自在欧美一区| 真人做人试看60分钟免费视频| 久久se精品一区二区三区| 国产无人区码一码二码三mba | 青青草国产久久精品| 国产办公室秘书无码精品99| 国产成人无码一区二区在线观看| 人妻丰满熟妇av无码区hd| 亚洲aⅴ在线无码播放毛片一线天| 成人午夜亚洲精品无码区| 成熟女人毛片www免费版在线| 又黄又爽又高潮免费毛片| 日本一卡2卡3卡4卡5卡精品视频| 无码视频在线观看| 99精品一区二区三区无码吞精| 日韩欧美亚洲综合久久影院d3 | 亚洲日本成本人观看| 国内精品伊人久久久久777| 亚洲日韩国产精品乱-久| 亚洲人成黄网站69影院| 激情欧美成人久久综合| 日本免费视频| 欧美人与动人物牲交免费观看| 韩国精品视频一区二区在线播放| 十八18禁国产精品www| 久久精品无码一区二区app| 亚洲熟女av乱码在线观看漫画|