在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PSMB1 Antibody

PSMB1 Antibody

  • 中文名稱：
    PSMB1兔多克隆抗體
  • 貨號：
    CSB-PA01395A0Rb
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Proteasome subunit beta 1 antibody at 2μg/ml
      Lane 1: EC109 whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 27 kDa
      Observed band size: 27 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PSMB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PSMB1
  • 別名：
    FLJ25321 antibody; HC5 antibody; KIAA1838 antibody; Macropain subunit C5 antibody; Multicatalytic endopeptidase complex subunit C5 antibody; Proteasome (prosome macropain) subunit beta type 1 antibody; Proteasome beta 1 subunit antibody; Proteasome component C5 antibody; Proteasome gamma chain antibody; Proteasome subunit beta type 1 antibody; Proteasome subunit beta type-1 antibody; Proteasome subunit HC5 antibody; PSB1_HUMAN antibody; PSC5 antibody; PSMB 1 antibody; PSMB1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Proteasome subunit beta type-1 protein (29-241AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PSMB1 Antibody (CSB-PA01395A0Rb)，的標記方式是Non-conjugated。對于PSMB1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA01395B0Rb PSMB1 Antibody, HRP conjugated ELISA
    FITC CSB-PA01395C0Rb PSMB1 Antibody, FITC conjugated
    Biotin CSB-PA01395D0Rb PSMB1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
  • 基因功能參考文獻：
    1. In vitro analyses demonstrated significantly reduced protease activity in proteasomes of individuals with G/G genotype compared with that of C/C carriers, despite that PSMB1 expression and proteasome assembly remained unaltered. PMID: 28733196
    2. The proteasome beta1 subunit plays a novel role in tumorigenesis by degrading p27Kip1. PMID: 23725357
    3. The mutated form of PSMB1 displayed increased nuclear translocation, resulting in activation of transcription in adipocytes. PMID: 23924720
    4. The proteasome was found to be activated in primary sjogren syndrome, with upregulation of gene expression of catalytic proteasome subunits. PMID: 23504381
    5. Follicular lymphoma patients with PSMB1 P11A (G allele) and low CD68 expression have significantly longer progression free survival with bortezomib-rituximab versus rituximab. PMID: 23549871
    6. PSMB1 is part of the transcriptional machinery required for gastrin stimulated expression of PAI-2 and Reg1. PMID: 23544109
    7. Expression of 26S proteasome beta(1)-subunit in NB4 cells increased after incubation with As(2)O(3). PMID: 19549367
    8. data defined a unique motif of BCL-3 that is needed for its recruitment to the proteasome and identified PSMB1 as a key protein required for the proteasome-mediated degradation of a nuclear and oncogenic IkappaB protein. PMID: 20558726

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1B family
  • 數據庫鏈接：

    HGNC: 9537

    OMIM: 602017

    KEGG: hsa:5689

    STRING: 9606.ENSP00000262193

    UniGene: Hs.352768



主站蜘蛛池模板： 中文日韩亚洲欧美制服| 色偷偷色噜噜狠狠网站久久| 国产亚洲精品久久久久久久久动漫| 天天燥日日燥| 无遮无挡爽爽免费视频| 精品无码国模私拍视频| 人妻熟女一区| 国产精品爽爽久久久久久竹菊| 亚洲国产成人超a在线播放| 137肉体摄影日本裸交| 国产精品美女久久久久久久久| 青娱乐极品视觉盛宴av| 337p亚洲日本中国大胆69| 最近更新中文字幕免费大全| 色欲色香天天天综合网www| 成人亚洲精品久久久久| 亚洲综合无码av一区二区三区| 欧美无人区码suv| 天天综合天天做天天综合| 亚洲中文字幕在线第二页| 国产成人高清亚洲一区妲妃| 永久黄网站色视频免费直播| 老太脱裤子让老头玩xxxxx| 亚洲精品色播一区二区| 亚洲情a成黄在线观看| 一品二品三品中文字幕| 成人无码视频在线观看大全| 99久久国产综合精品1| 66亚洲一卡2卡新区成片发布| 娇妻被黑人粗大高潮白浆| 在线人视频观看免费| 日本丰满熟妇hd| 久久精品a亚洲国产v高清不卡| 国产成人午夜福利在线小电影| 亚洲一卡2卡3卡4卡5卡乱码观看 | 亚洲国产成人av在线观看| 色综久久综合桃花网国产精品| 又黄又爽又色视频| 国产9 9在线 | 中文| 久久久久亚洲精品天堂| 欧美精品一区二区精品久久|