在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PRR11 Antibody, FITC conjugated

  • 中文名稱:
    PRR11兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA836225LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PRR11 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PRR11
  • 別名:
    FLJ11029 antibody; Homo sapiens proline rich 11 antibody; Proline rich protein 11 antibody; Proline-rich protein 11 antibody; PRR 11 antibody; Prr11 antibody; PRR11_HUMAN antibody; transcription repressor of MHCII antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Proline-rich protein 11 protein (1-360AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a critical role in cell cycle progression.
  • 基因功能參考文獻:
    1. PRR11 plays an oncogenic role in hepatocellular carcinoma (HCC) progression, through activating the Wnt/beta-catenin signaling pathway, and may represent a valuable prognostic marker and therapeutic target for HCC. PMID: 30248355
    2. PRR11 positively regulated cell proliferation-related proteins, including c-myc and cyclin D1, and increased and decreased the expression of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 and PRR11 expression was mediated by the phosphoinositide 3-kinase/AKT/beta-catenin signaling pathway. PMID: 30165366
    3. these findings further illustrate the suppressive role of miR-195 in prostate cancer (PCa), and indicate a novel role of PRR11 in PCa. Importantly, the newly identified miR-195/PRR11 axis may aid with identifying potential therapeutic targets in PCa. PMID: 29393495
    4. PRR11 regulated self-renewal and tumorigenicity of gastric cancer stem cells through MAPK signaling, and could be used as a therapeutic target for gastric cancer. PMID: 30007956
    5. these findings indicated that miR-144-3p induced cell cycle arrest and apoptosis in pancreatic cancer by targeting PRR11. PMID: 28574724
    6. p53 negatively regulates the expression of the PRR11-SKA2 bidirectional transcription unit through NF-Y, suggesting that the inability to repress the PRR11-SKA2 bidirectional transcription unit after loss of p53 might contribute to tumorigenesis. PMID: 28257042
    7. Microarray analysis revealed that several genes involved in cell proliferation, cell adhesion, and cell migration were altered in PRR11-knockout cells. PMID: 25971332
    8. PRR11 may be widely activated in human gastric cancer. PMID: 26252227
    9. Targeted depletion of PRR11 caused a dramatic cell cycle arrest followed by massive apoptotic cell death, and eventually resulted in a significant decrease in growth and viability in lung cancer cell lines. PMID: 25973065
    10. PRR11-SKA2 bidirectional transcription unit, which is a novel direct target of NF-Y, is essential for the accelerated proliferation and motility of lung cancer cells PMID: 26162986
    11. Overexpression of PRR11 inhibits cell proliferation and induces premature chromatin condensation. PMID: 25666944
    12. our results strongly demonstrated that this newly identified gene, PRR11, had a critical role in both cell cycle progression and tumorigenesis, and might serve as a novel potential target in the diagnosis and/or treatment of human lung cancer. PMID: 23246489
    13. the apparent occurrence of an unusual TG 3' splice site in intron 10 is discussed PMID: 17672918

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 25619

    OMIM: 615920

    KEGG: hsa:55771

    STRING: 9606.ENSP00000262293

    UniGene: Hs.631750



主站蜘蛛池模板: 欧美极品video粗暴| 国产又粗又猛又大爽又黄| 成人性生交大免费看| 久久久午夜精品福利内容| 2012中文字幕在线视频| 国产成人av区一区二区三| 亚洲精品国产一区二区的区别 | 国产精品亚洲a∨天堂| 无套中出丰满人妻无码| 欧美老妇与zozozo交| 免费永久看黄神器无码软件| 欧美性猛少妇xxxxx免费| 国产精品v片在线观看不卡| 特级做a爰片毛片免费看108| 午夜伦4480yy私人影院| 国产亚洲精品久久久闺蜜| 午夜精品久久久久久| 亚洲国产精品18久久久久久| 国产偷窥熟精品视频| 国产v在线在线观看视频免费| 天天躁日日躁狠狠躁欧美老妇小说| 国产日产欧产精品| 亚洲国产成人高清影视| 无码超乳爆乳中文字幕| 少妇邻居内射在线| 欧洲vat一区二区三区| 国产成人精品自在线拍| 国产免费无遮挡吸乳视频 | 一本大道久久香蕉成人网| 九九九精品成人免费视频小说| 精品国产偷窥一区二区| 日韩精品无码一本二本三本| 97国产在线看片免费人成视频| 92国产精品午夜福利免费| 精品一区二区三区在线观看视频| 亚洲成在线aⅴ免费视频| 国产精品二区一区二区aⅴ污介绍| 亚洲五月综合缴情在线| 免费精品国偷自产在线在线| 少妇极品熟妇人妻200片| 精品无码国产一区二区三区51安|