在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PRR11 Antibody, Biotin conjugated

  • 中文名稱:
    PRR11兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA836225LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PRR11 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PRR11
  • 別名:
    FLJ11029 antibody; Homo sapiens proline rich 11 antibody; Proline rich protein 11 antibody; Proline-rich protein 11 antibody; PRR 11 antibody; Prr11 antibody; PRR11_HUMAN antibody; transcription repressor of MHCII antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Proline-rich protein 11 protein (1-360AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a critical role in cell cycle progression.
  • 基因功能參考文獻:
    1. PRR11 plays an oncogenic role in hepatocellular carcinoma (HCC) progression, through activating the Wnt/beta-catenin signaling pathway, and may represent a valuable prognostic marker and therapeutic target for HCC. PMID: 30248355
    2. PRR11 positively regulated cell proliferation-related proteins, including c-myc and cyclin D1, and increased and decreased the expression of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 and PRR11 expression was mediated by the phosphoinositide 3-kinase/AKT/beta-catenin signaling pathway. PMID: 30165366
    3. these findings further illustrate the suppressive role of miR-195 in prostate cancer (PCa), and indicate a novel role of PRR11 in PCa. Importantly, the newly identified miR-195/PRR11 axis may aid with identifying potential therapeutic targets in PCa. PMID: 29393495
    4. PRR11 regulated self-renewal and tumorigenicity of gastric cancer stem cells through MAPK signaling, and could be used as a therapeutic target for gastric cancer. PMID: 30007956
    5. these findings indicated that miR-144-3p induced cell cycle arrest and apoptosis in pancreatic cancer by targeting PRR11. PMID: 28574724
    6. p53 negatively regulates the expression of the PRR11-SKA2 bidirectional transcription unit through NF-Y, suggesting that the inability to repress the PRR11-SKA2 bidirectional transcription unit after loss of p53 might contribute to tumorigenesis. PMID: 28257042
    7. Microarray analysis revealed that several genes involved in cell proliferation, cell adhesion, and cell migration were altered in PRR11-knockout cells. PMID: 25971332
    8. PRR11 may be widely activated in human gastric cancer. PMID: 26252227
    9. Targeted depletion of PRR11 caused a dramatic cell cycle arrest followed by massive apoptotic cell death, and eventually resulted in a significant decrease in growth and viability in lung cancer cell lines. PMID: 25973065
    10. PRR11-SKA2 bidirectional transcription unit, which is a novel direct target of NF-Y, is essential for the accelerated proliferation and motility of lung cancer cells PMID: 26162986
    11. Overexpression of PRR11 inhibits cell proliferation and induces premature chromatin condensation. PMID: 25666944
    12. our results strongly demonstrated that this newly identified gene, PRR11, had a critical role in both cell cycle progression and tumorigenesis, and might serve as a novel potential target in the diagnosis and/or treatment of human lung cancer. PMID: 23246489
    13. the apparent occurrence of an unusual TG 3' splice site in intron 10 is discussed PMID: 17672918

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 25619

    OMIM: 615920

    KEGG: hsa:55771

    STRING: 9606.ENSP00000262293

    UniGene: Hs.631750



主站蜘蛛池模板: 色国产精品一区在线观看| 狼友av永久网站免费观看孕交| 好吊射视频988gaocom| 国产成av人片在线观看无码| 老熟女高潮喷水了| 日本午夜免费福利视频| 久久精品无码免费不卡| 国产在线无码视频一区二区三区| 精品亚洲aⅴ在线无码播放| 日本在线视频www鲁啊鲁| 不卡av电影在线| 国精品午夜福利视频不卡| 99久热re在线精品视频| 麻豆国产av丝袜白领传媒| 我把护士日出水了视频90分钟| 美女高潮黄又色高清视频免费| 亚洲中文字幕丝祙制服| 东京热加勒比视频一区| 色综合视频一区二区三区44| 日韩夜夜高潮夜夜爽无码| 天天天欲色欲色www免费| 亚洲另类成人小说综合网| 日本xxxx丰满老妇| 特级做a爰片毛片免费看| 无码av免费精品一区二区三区| 欧美成人免费全部| 亚洲一码二码三码精华液| 天天鲁在视频在线观看| 两个奶头被吃高潮视频| 国产精品成人久久电影| 国产八十老太另类| 人人妻人人澡人人爽精品欧美| 艳妇乳肉豪妇荡乳av无码福利 | 久久久久久久综合狠狠综合| 亚洲 欧美 国产 日韩 精品| 欧美日韩无套内射另类| 欧美精品亚洲精品日韩专区| 色综合久久久无码中文字幕波多 | 最新国产在线拍揄自揄视频| 成人h视频在线观看| 国色精品卡一卡2卡3卡4卡在线 |