在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PRKAG1 Antibody, HRP conjugated

PRKAG1 Antibody, HRP conjugated

  • 中文名稱：
    PRKAG1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA01149B0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PRKAG1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    5' AMP activated protein kinase gamma 1 subunit antibody; 5' AMP activated protein kinase subunit gamma 1 antibody; 5''-AMP-activated protein kinase subunit gamma-1 antibody; AAKG1_HUMAN antibody; AMP activated protein kinase noncatalytic gamma 1 subunit antibody; AMPK gamma 1 chain antibody; AMPK gamma1 antibody; AMPK subunit gamma-1 antibody; AMPKg antibody; MGC8666 antibody; PRKAG 1 antibody; PRKAG1 antibody; Protein kinase AMP activated gamma 1 non catalytic subunit antibody; protein kinase; AMP-activated; noncatalytic gamma-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 5'-AMP-activated protein kinase subunit gamma-1 protein (1-331AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
  • 基因功能參考文獻：
    1. Data suggest different gamma-isoforms in AMPK can have different effects on enzyme activation; here, activation of AMPK by compound 991 is greater if AMPK contains PRKAG2 versus PRKAG1 or PRKAG3. PMID: 28302767
    2. Pin1 plays an important role in the pathogenic mechanisms underlying impaired glucose and lipid metabolism, functioning as a negative regulator of AMPK PMID: 26276391
    3. Letter: report PRKAG1 frameshift mutations in colorectal cancer. PMID: 25267969
    4. Electrogenic phosphate transport in sodium/phosphate cotransporter NaPi-IIa-expressing Xenopus oocytes is markedly decreased by the coexpression of constitutively active AMPKgammaR70Q, but not of AMPK(alphaK45R). PMID: 24356547
    5. PRKAG1 interacts with DSCAM through its gamma subunit, and netrin-1 activates AMPK phosphorylation in cortical neurons. PMID: 23479427
    6. Conclude that cTnI phosphorylation by AMPK may represent a novel mechanism of regulation of cardiac function. PMID: 22456184
    7. Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells. PMID: 19052260

    顯示更多

    收起更多

  • 蛋白家族：
    5'-AMP-activated protein kinase gamma subunit family
  • 數據庫鏈接：

    HGNC: 9385

    OMIM: 602742

    KEGG: hsa:5571

    STRING: 9606.ENSP00000323867

    UniGene: Hs.530862



主站蜘蛛池模板： 一本丁香综合久久久久不卡网站| 巨人精品福利官方导航| 精品国产18久久久久久| 9re热国产这里只有精品 | 国产人妻人伦精品1国产丝袜| 熟妇熟女乱妇乱女网站| 人人狠狠久久亚洲综合88| 亚洲精品无码ma在线观看| 国产欧美日韩综合精品一区二区| 亚洲一线二线三线写真| 果冻传媒mv免费播放在线观看 | 欧洲精品一线二线三线区别| 国产剧情av麻豆香蕉精品| 色天天天综合色天天| 精品国产亚洲午夜精品av| 夜夜躁天天躁很很躁| 中文字幕av一区二区三区人妻少妇| 午夜dj高清免费观看视频| 欧美成aⅴ人高清ww| 人妻无码第一区二区三区 | 中文资源在线天堂库8| 国产女人18毛片水真多18精品| 美女国产毛片a区内射| 日韩一卡二卡三卡四卡免费观在线| 国产成人无码视频网站在线观看| 67194熟妇在线观看线路1| 韩国精品福利一区二区三区| 在线播放人成视频观看| 伊人久久大香线蕉成人| 51国偷自产一区二区三区| 中文字幕日本特黄aa毛片| 丰满的少妇邻居中文bd| 国产人妻人伦精品1国产盗摄| 欧美巨鞭大战丰满少妇| 亚洲国产精品无码久久久动漫| 中文精品久久久久鬼色| 亚洲日韩国产成网在线观看| 真人做人试看60分钟免费视频| 国产98在线 | 免费| 中文字幕无码精品亚洲35| 色综合av男人的天堂伊人|