在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PRKAG1 Antibody, HRP conjugated

PRKAG1 Antibody, HRP conjugated

  • 中文名稱：
    PRKAG1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA01149B0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PRKAG1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    5' AMP activated protein kinase gamma 1 subunit antibody; 5' AMP activated protein kinase subunit gamma 1 antibody; 5''-AMP-activated protein kinase subunit gamma-1 antibody; AAKG1_HUMAN antibody; AMP activated protein kinase noncatalytic gamma 1 subunit antibody; AMPK gamma 1 chain antibody; AMPK gamma1 antibody; AMPK subunit gamma-1 antibody; AMPKg antibody; MGC8666 antibody; PRKAG 1 antibody; PRKAG1 antibody; Protein kinase AMP activated gamma 1 non catalytic subunit antibody; protein kinase; AMP-activated; noncatalytic gamma-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 5'-AMP-activated protein kinase subunit gamma-1 protein (1-331AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
  • 基因功能參考文獻：
    1. Data suggest different gamma-isoforms in AMPK can have different effects on enzyme activation; here, activation of AMPK by compound 991 is greater if AMPK contains PRKAG2 versus PRKAG1 or PRKAG3. PMID: 28302767
    2. Pin1 plays an important role in the pathogenic mechanisms underlying impaired glucose and lipid metabolism, functioning as a negative regulator of AMPK PMID: 26276391
    3. Letter: report PRKAG1 frameshift mutations in colorectal cancer. PMID: 25267969
    4. Electrogenic phosphate transport in sodium/phosphate cotransporter NaPi-IIa-expressing Xenopus oocytes is markedly decreased by the coexpression of constitutively active AMPKgammaR70Q, but not of AMPK(alphaK45R). PMID: 24356547
    5. PRKAG1 interacts with DSCAM through its gamma subunit, and netrin-1 activates AMPK phosphorylation in cortical neurons. PMID: 23479427
    6. Conclude that cTnI phosphorylation by AMPK may represent a novel mechanism of regulation of cardiac function. PMID: 22456184
    7. Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells. PMID: 19052260

    顯示更多

    收起更多

  • 蛋白家族：
    5'-AMP-activated protein kinase gamma subunit family
  • 數據庫鏈接：

    HGNC: 9385

    OMIM: 602742

    KEGG: hsa:5571

    STRING: 9606.ENSP00000323867

    UniGene: Hs.530862



主站蜘蛛池模板： 国产按头口爆吞精在线视频| 窝窝午夜理论片影院| 国产精品毛片无遮挡高清| 人妻人人澡人人添人人爽 | 99热国产这里只有精品9| 欧美处交wwwvideos另类| 日本精品aⅴ一区二区三区| 三上悠亚ssⅰn939无码播放| 欧美男生射精高潮视频网站 | 成人区人妻精品一区二区不卡视频 | 亚洲精品偷拍影视在线观看| 日韩欧美在线综合网| 欧美性xxxxx极品少妇| 成 人 亚洲 综合天堂 | 99久久国产精品免费高潮| 任我橹这里只有精品 在线视频 | 国产美女被遭强高潮免费网站| 大j8黑人w巨大888a片| 亚洲国产精品无码久久| 国产日韩在线视看第一页| 女邻居丰满的奶水| 成人高潮视频在线观看| 人妻熟女一区二区aⅴ水野朝阳| 日本一卡2卡3卡四卡精品网站| 久久精品国产免费观看| 欧美18精品久久久无码午夜福利| 精品999日本久久久影院| 亚洲高清毛片一区二区| 无码人妻精品一区二区在线视频| 日韩av无码成人无码免费| 亚洲人成电影免费观看在线看| 国产乱子伦一区二区三区=| 99久久99久久精品国产片果冻| 欧美黑人性暴力猛交喷水黑人巨大| 无码人妻精品一区二区三区免费| 日韩免费无码专区精品观看 | 国产xxxx做受视频| 国产亚洲中文字幕在线制服| 欧美喷潮久久久xxxxx| 黑人巨茎大战欧美白妇| 国产成人亚洲精品无码车a|