在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PIK3R4 Antibody

PIK3R4 Antibody

  • 中文名稱：
    PIK3R4兔多克隆抗體
  • 貨號：
    CSB-PA785311
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA785311(PIK3R4 Antibody) at dilution 1/85, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA785311(PIK3R4 Antibody) at dilution 1/85, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    MGC102700 antibody; P150 antibody; Phosphatidylinositol 3 kinase associated p150 antibody; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4 antibody; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4 p150 antibody; Phosphoinositide 3 kinase adaptor protein antibody; Phosphoinositide 3 kinase regulatory subunit 4 antibody; Phosphoinositide 3 kinase regulatory subunit 4 p150 antibody; Phosphoinositide 3 kinase regulatory subunit polypeptide 4 antibody; Phosphoinositide 3 kinase regulatory subunit polypeptide 4 p150 antibody; Phosphoinositide 3-kinase adaptor protein antibody; Phosphoinositide 3-kinase regulatory subunit 4 antibody; PI3 kinase p150 subunit antibody; PI3-kinase p150 subunit antibody; PI3-kinase regulatory subunit 4 antibody; PI3R4_HUMAN antibody; PIK3R 4 antibody; PIK3R4 antibody; VPS 15 antibody; VPS15 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human PIK3R4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:100-1:300
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2.
  • 基因功能參考文獻：
    1. A missense mutation in PIK3R4 (phosphoinositide 3-kinase regulatory subunit 4, named VPS15) in a family with a ciliopathy phenotype is identified. Besides being required for trafficking and autophagy, we show that VPS15 regulates primary cilium length in human fibroblasts. PMID: 27882921
    2. Both Danon Disease and glycogen storage disease type II show accumulation and altered localization of VPS15 in autophagy-incompetent fibers. However, TFEB displays a different pattern between these two lysosomal storage diseases PMID: 28102838
    3. High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia. PMID: 25840748
    4. A specific sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates both receptor degradation and cytokinesis, whereas ATG14L, a PI3K-III subunit involved in autophagy, is not required. PMID: 20643123
    5. hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells PMID: 18957027

    顯示更多

    收起更多

  • 亞細胞定位：
    Late endosome. Cytoplasmic vesicle, autophagosome. Membrane; Lipid-anchor.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 8982

    OMIM: 602610

    KEGG: hsa:30849

    STRING: 9606.ENSP00000349205

    UniGene: Hs.149032



主站蜘蛛池模板： 好硬好湿好爽好深视频| av无码不卡一区二区三区| 夜夜欢性恔真人免费视频| 国产97色在线 | 欧洲| 亚洲日本va中文字幕久久| 国产精品www夜色视频| 四虎影视国产精品久久| 天堂在线www中文| 男女猛烈无遮挡免费视频app | 亚洲国产精品日韩av不卡在线| 日本少妇xxx做受| 久久综合av色老头免费观看| 精品人妻无码区二区三区| 澳门永久av免费网站| 国产又大又粗又爽的毛片| 秋霞鲁丝片av无码| 97无码免费人妻超级碰碰碰碰| 少妇人妻无码专区视频| 236宅宅理论片免费| 人妻精品久久久久中文字幕| 久久精品人人做人人爽老司机| 最激烈的床震娇喘视频出水| 免费人成在线观看| 10000部拍拍拍免费视频| 亚洲国产精品不卡av在线| 亚洲制服丝中文字幕| 男人边吃奶边做好爽免费视频| 99久久99久久精品免费看蜜桃| 欧美精品国产aⅴ一区二区在线 | 熟女人妻在线视频| 麻豆国产在线精品国偷产拍| 国产高清视频在线观看97| 99久久99久久免费精品蜜桃| 国产成人久久精品77777综合| 亚洲最大成人网色| 国产粉嫩嫩00在线正在播放| 国产午夜福利在线观看视频_ | 99re久久精品国产| 内射夜晚在线观看| 国内一区二区三区香蕉aⅴ| 久久人人97超碰国产公开|