在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PIK3R4 Antibody, FITC conjugated

PIK3R4 Antibody, FITC conjugated

  • 中文名稱：
    PIK3R4兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA858716LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PIK3R4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    MGC102700 antibody; P150 antibody; Phosphatidylinositol 3 kinase associated p150 antibody; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4 antibody; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4 p150 antibody; Phosphoinositide 3 kinase adaptor protein antibody; Phosphoinositide 3 kinase regulatory subunit 4 antibody; Phosphoinositide 3 kinase regulatory subunit 4 p150 antibody; Phosphoinositide 3 kinase regulatory subunit polypeptide 4 antibody; Phosphoinositide 3 kinase regulatory subunit polypeptide 4 p150 antibody; Phosphoinositide 3-kinase adaptor protein antibody; Phosphoinositide 3-kinase regulatory subunit 4 antibody; PI3 kinase p150 subunit antibody; PI3-kinase p150 subunit antibody; PI3-kinase regulatory subunit 4 antibody; PI3R4_HUMAN antibody; PIK3R 4 antibody; PIK3R4 antibody; VPS 15 antibody; VPS15 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Phosphoinositide 3-kinase regulatory subunit 4 protein (1300-1358AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2.
  • 基因功能參考文獻：
    1. A missense mutation in PIK3R4 (phosphoinositide 3-kinase regulatory subunit 4, named VPS15) in a family with a ciliopathy phenotype is identified. Besides being required for trafficking and autophagy, we show that VPS15 regulates primary cilium length in human fibroblasts. PMID: 27882921
    2. Both Danon Disease and glycogen storage disease type II show accumulation and altered localization of VPS15 in autophagy-incompetent fibers. However, TFEB displays a different pattern between these two lysosomal storage diseases PMID: 28102838
    3. High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia. PMID: 25840748
    4. A specific sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates both receptor degradation and cytokinesis, whereas ATG14L, a PI3K-III subunit involved in autophagy, is not required. PMID: 20643123
    5. hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells PMID: 18957027

    顯示更多

    收起更多

  • 亞細胞定位：
    Late endosome. Cytoplasmic vesicle, autophagosome. Membrane; Lipid-anchor.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 8982

    OMIM: 602610

    KEGG: hsa:30849

    STRING: 9606.ENSP00000349205

    UniGene: Hs.149032



主站蜘蛛池模板： 无码日韩人妻av一区免费| 免费观看激色视频网站| 亚洲综合一区二区三区四区五区| 精品一区二区三区国产在线观看 | 日韩亚洲国产激情一区浪潮av| 国产亚州精品女人久久久久久| 国产三级久久久精品麻豆三级| 欧美激情一区二区成人| 一个人看的视频www在线| 欧美饥渴熟妇高潮喷水水 | 亚洲国产成人av人片久久| 99精品日本二区留学生| 亚洲成a人无码| 国产乡下妇女做爰| 熟女人妻av粗壮巨龙| 人狥杂交一区欧美二区| 无码乱码av天堂一区二区| 国产精品成人国产乱| 九九热爱视频精品| 久久综合伊人中文字幕| 猫咪www免费人成人入口| 99久久无色码中文字幕| 18禁裸男晨勃露j毛网站| 大肉大捧一进一出好爽视频mba| h肉动漫无码无修6080动漫网| 欧美黑人异族videos| 国精产品蘑菇一区一区有限| 亚洲午夜成人片| 俄罗斯大荫蒂女人毛茸茸| 2021少妇久久久久久久久久| 成人乱码一区二区三区av| 免费人成视频在线| 97久章草在线视频播放| 人妻av乱片av出轨av| 久久久精品人妻无码专区不卡| 国产中老年妇女精品| 日日碰狠狠躁久久躁96| 最近最新中文字幕高清免费| 人妻熟妇乱又伦精品视频中文字幕| 欧美成人精精品一区二区| 动漫精品视频一区二区三区|