在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PHLDA3 Antibody, HRP conjugated

PHLDA3 Antibody, HRP conjugated

  • 中文名稱：
    PHLDA3兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA017932LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PHLDA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PHLDA3
  • 別名：
    PHLA3_HUMAN antibody; PHLDA 3 antibody; phlda3 antibody; Pleckstrin homology like domain family A member 2 antibody; Pleckstrin homology like domain family A member 3 antibody; Pleckstrin homology-like domain family A member 3 antibody; TDAG51/Ipl homolog 1 antibody; TDAG51/Ipl homologue 1 antibody; TIH 1 antibody; TIH1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
  • 基因功能參考文獻：
    1. although iPSCs and ESCs share lots of common features, we did not find that PHLDA3 is important to ES cell differentiation. PMID: 28588267
    2. Low PHLDA3 expression in ESCC may be predictive of tumor recurrence suggesting that Akt activation may be a therapeutic target in ESCCs PMID: 25667479
    3. Results indicate that tumor suppressor PHLDA3-mediated pathway is important in the development of pancreatic neuroendocrine tumors (PanNETs). PMID: 24912192
    4. findings indicate somatic mutation of PHLDA3 is rare in common cancer types; PHLDA3 expression was lost in 22% of prostate cancers; these results indicate that PHLDA3 are altered in prostate cancers by loss of expression PMID: 21753719
    5. Study identifies PHLDA3 as a p53 target gene that encodes a PH domain-only protein and finds that PHLDA3 competes with the PH domain of Akt for binding of membrane lipids, inhibiting Akt translocation to the cellular membrane and activation. PMID: 19203586

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    PHLDA3 family
  • 組織特異性：
    Widely expressed with lowest expression in liver and spleen.
  • 數據庫鏈接：

    HGNC: 8934

    OMIM: 607054

    KEGG: hsa:23612

    STRING: 9606.ENSP00000356278

    UniGene: Hs.153944



主站蜘蛛池模板： 97狠狠狠狼鲁亚洲综合网| 日产日韩亚洲欧美综合下载 | 男人扒女人添高潮视频| 人妻少妇精品无码专区二区| 国产真实伦对白全集| 精品玖玖玖视频在线观看| 99久久精品午夜一区二区| 国产山东熟女48嗷嗷叫| 国产乱子伦一区二区三区=| 少妇高潮灌满白浆毛片免费看| 亚洲精品国产品国语在线| 午夜影视啪啪免费体验区入口 | 国产三级精品三级在线专区| 三个男吃我奶头一边一个视频 | 高潮添下面视频免费看| 国产精品久久久久秋霞鲁丝| 巨熟乳波霸若妻在线播放| 强行征服邻居人妻淑敏| 一二三四在线视频观看社区| 亚洲精品456在线播放| 亚洲精品乱码久久久久久蜜桃不卡| 久久99国产综合精品女同| 国产md视频一区二区三区| 熟妇好大好深好满好爽| 欧洲多毛裸体xxxxx| 人妻无码久久中文字幕专区| 宝贝腿开大点我添添公视频免费| 天天躁日日躁狠狠躁免费麻豆| 亚洲欧美日韩精品色xxx| а√天堂www在线а√天堂视频| 鲁鲁夜夜天天综合视频| 蜜桃av麻豆av果冻传媒| 精品久久久无码人妻字幂| 欧美亚洲精品中文字幕乱码| 国语自产拍精品香蕉在线播放 | 国内精品久久久久av福利秒拍| 国产精品国产三级国产av主播| 少妇愉情理伦片丰满丰满午夜| 日本中文字幕一区二区有码在线| 蜜桃视频在线观看免费网址入口| 男女裸体影院高潮|