在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PHLDA3 Antibody, FITC conjugated

PHLDA3 Antibody, FITC conjugated

  • 中文名稱：
    PHLDA3兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA017932LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PHLDA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PHLDA3
  • 別名：
    PHLA3_HUMAN antibody; PHLDA 3 antibody; phlda3 antibody; Pleckstrin homology like domain family A member 2 antibody; Pleckstrin homology like domain family A member 3 antibody; Pleckstrin homology-like domain family A member 3 antibody; TDAG51/Ipl homolog 1 antibody; TDAG51/Ipl homologue 1 antibody; TIH 1 antibody; TIH1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
  • 基因功能參考文獻(xiàn)：
    1. although iPSCs and ESCs share lots of common features, we did not find that PHLDA3 is important to ES cell differentiation. PMID: 28588267
    2. Low PHLDA3 expression in ESCC may be predictive of tumor recurrence suggesting that Akt activation may be a therapeutic target in ESCCs PMID: 25667479
    3. Results indicate that tumor suppressor PHLDA3-mediated pathway is important in the development of pancreatic neuroendocrine tumors (PanNETs). PMID: 24912192
    4. findings indicate somatic mutation of PHLDA3 is rare in common cancer types; PHLDA3 expression was lost in 22% of prostate cancers; these results indicate that PHLDA3 are altered in prostate cancers by loss of expression PMID: 21753719
    5. Study identifies PHLDA3 as a p53 target gene that encodes a PH domain-only protein and finds that PHLDA3 competes with the PH domain of Akt for binding of membrane lipids, inhibiting Akt translocation to the cellular membrane and activation. PMID: 19203586

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    PHLDA3 family
  • 組織特異性：
    Widely expressed with lowest expression in liver and spleen.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8934

    OMIM: 607054

    KEGG: hsa:23612

    STRING: 9606.ENSP00000356278

    UniGene: Hs.153944



主站蜘蛛池模板： 国精产品一区一区三区| 国产免费人成网站x8x8| 少妇人妻无码专区毛片| 无码视频一区二区三区在线观看| 国产精品亚洲专区无码牛牛| 国产xxxx做受视频| 四虎永久在线精品免费观看| 精品国偷自产在线视频| 福利姬液液酱喷水| 在线精品动漫一区二区无码| 亚洲 欧美 动漫 少妇 自拍| 日本一区不卡高清更新二区 | 好吊妞国产欧美日韩免费观看| 色偷偷噜噜噜亚洲男人 | 亚洲小说区图片区另类春色| 国产成人精品永久免费视频| 天天天狠天天碰天天爱| 好吊色欧美一区二区三区视频| 亚洲色成人www永久网站| 国产成人无码av片在线观看不卡| 亚洲国内成人精品网| 精品国产乱码久久久久久婷婷| 亚洲精品久久久久中文第一幕| 日本一道本高清一区二区| av在线无码专区一区| 欧美日韩精品人妻狠狠躁免费视频| 日韩高清亚洲日韩精品一区| 久久精品国产久精国产爱| 无码人妻精品一区二区蜜桃色欲| 欧美亚洲精品中文字幕乱码| 2020年国产精品| 久久久一本精品99久久精品88| 一区二区三区视频| 久久中文字幕无码a片不卡古代 | 久久综合色_综合色88| 在线精品自偷自拍无码| 99久久人妻精品免费二区| 人妻综合专区第一页| 欧美人伦禁忌dvd放荡欲情| 99精品人妻无码专区在线视频区| 久久久水蜜桃国产成人网站|