在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PEX14 Antibody

  • 中文名稱:
    PEX14兔多克隆抗體
  • 貨號:
    CSB-PA017800ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA017800ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) PEX14 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PEX14
  • 別名:
    dJ734G22.2 antibody; NAPP2 antibody; NF E2 associated polypeptide 2 antibody; Peroxin 14 antibody; Peroxin-14 antibody; Peroxisomal biogenesis factor 14 antibody; Peroxisomal membrane anchor protein PEX14 antibody; Peroxisomal membrane anchor protein Pex14p antibody; Peroxisomal membrane protein PEX14 antibody; pex14 antibody; PEX14_HUMAN antibody; Pex14p antibody; PTS1 receptor docking protein antibody; PTS1 receptor-docking protein antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Peroxisomal membrane protein PEX14 protein (118-377AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
  • 基因功能參考文獻:
    1. data reveal subpopulations of peroxisomes showing only weak colocalization between PEX14 and PEX5 or PEX11 but at the same time a clear compartmentalized organization. This compartmentalization, which was less evident in cases of strong colocalization, indicates dynamic protein reorganization linked to changes occurring in the peroxisomes. PMID: 27311714
    2. PEX14 is the 13th PEX gene responsible for peroxisome biogenesis disorders. Thus far, only two patients with PEX14 deficiency have been reported. PMID: 26627464
    3. The novel Pex14-binding site may represent the initial tethering site of Pex5 from which the cargo-loaded receptor is further processed in a sequential manner. PMID: 24235149
    4. interaction of PEX5 with catalase and PEX14 PMID: 21976670
    5. PEX14 is a multi-tasking protein that not only facilitates peroxisomal protein import but is also required for peroxisome motility by serving as membrane anchor for microtubules. PMID: 21525035
    6. Serves as a transcriptional corepressor in addition to its peroxisomal function. PMID: 11863372
    7. peroxisomal localization of Pex14p is affected by Pex13p PMID: 14715663
    8. a new complementation group of the peroxisome biogenesis disorders with PEX14 as the defective gene PMID: 15146459
    9. This report represents the second PEX14-deficiency associated with Zellweger syndrome and the first documentation of a PEX14-deficient patient with detailed clinical follow-up and biochemical, morphological, and radiological data. PMID: 18285423
    10. N-terminal domain of Pex14, Pex14(N), adopts a three-helical fold. Pex5 and Pex19 ligand helices bind competitively to the same surface in Pex14(N) albeit with opposite directionality. PMID: 19197237
    11. analysis of the human Pex5.Pex14.PTS1 protein complex structure obtained by small angle X-ray scattering PMID: 19584060

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Peroxisome biogenesis disorder complementation group K (PBD-CGK); Peroxisome biogenesis disorder 13A (PBD13A)
  • 亞細胞定位:
    Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Peroxin-14 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 8856

    OMIM: 601791

    KEGG: hsa:5195

    STRING: 9606.ENSP00000349016

    UniGene: Hs.149983



主站蜘蛛池模板: 亚洲欧美第一成人网站7777| 欧美人与动牲交zooz男人| 亚洲日韩国产精品乱-久| 国产成人亚洲精品无码最新| 婷婷成人五月综合激情| 国产精品区av| 亚洲视频在线观看| 国产嫖妓风韵犹存对白| 亚洲狠狠色丁香婷婷综合| 四虎永久在线精品免费无码| 国内精品久久人妻互换| 熟女少妇人妻中文字幕| 亚洲日韩av一区二区三区中文| 亚洲色欲天天天堂色欲网| 日韩欧美激情兽交| 亚洲成av人无码综合在线观看| 中文字幕乱妇无码av在线| 99久久无色码中文字幕| 亚洲爆乳成av人在线蜜芽| 久久国产加勒比精品无码| 人妻 色综合网站| 国产精品国产成人国产三级| 无遮无挡爽爽免费视频| 强制高潮18xxxxhd日韩| 国产精品美女久久久久久久久| 日韩av高清在线观看| 亚洲vav在线男人的天堂| 国产美女遭强高潮网站观看| 人妻熟女一区二区aⅴ千叶宁真| 亚洲日韩一页精品发布| 黑人巨大无码中文字幕无码| 亚洲成成熟女人专区| 加勒比久久综合网天天| 中国熟妇牲交视频| 成 人影片 免费观看在线| 欧美午夜成人片在线观看| 非洲人与性动交ccoo| 精品日产卡一卡二卡麻豆| 精品无码成人久久久久久| 成人无码视频| 韩国三级中文字幕hd久久精品|