在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PEX14 Antibody

  • 中文名稱:
    PEX14兔多克隆抗體
  • 貨號:
    CSB-PA775947
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from A549 cells, using PEX14 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PEX14 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PEX14 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PEX14
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from internal of Human PEX14.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
  • 基因功能參考文獻:
    1. data reveal subpopulations of peroxisomes showing only weak colocalization between PEX14 and PEX5 or PEX11 but at the same time a clear compartmentalized organization. This compartmentalization, which was less evident in cases of strong colocalization, indicates dynamic protein reorganization linked to changes occurring in the peroxisomes. PMID: 27311714
    2. PEX14 is the 13th PEX gene responsible for peroxisome biogenesis disorders. Thus far, only two patients with PEX14 deficiency have been reported. PMID: 26627464
    3. The novel Pex14-binding site may represent the initial tethering site of Pex5 from which the cargo-loaded receptor is further processed in a sequential manner. PMID: 24235149
    4. interaction of PEX5 with catalase and PEX14 PMID: 21976670
    5. PEX14 is a multi-tasking protein that not only facilitates peroxisomal protein import but is also required for peroxisome motility by serving as membrane anchor for microtubules. PMID: 21525035
    6. Serves as a transcriptional corepressor in addition to its peroxisomal function. PMID: 11863372
    7. peroxisomal localization of Pex14p is affected by Pex13p PMID: 14715663
    8. a new complementation group of the peroxisome biogenesis disorders with PEX14 as the defective gene PMID: 15146459
    9. This report represents the second PEX14-deficiency associated with Zellweger syndrome and the first documentation of a PEX14-deficient patient with detailed clinical follow-up and biochemical, morphological, and radiological data. PMID: 18285423
    10. N-terminal domain of Pex14, Pex14(N), adopts a three-helical fold. Pex5 and Pex19 ligand helices bind competitively to the same surface in Pex14(N) albeit with opposite directionality. PMID: 19197237
    11. analysis of the human Pex5.Pex14.PTS1 protein complex structure obtained by small angle X-ray scattering PMID: 19584060

    顯示更多

    收起更多

  • 相關疾病:
    Peroxisome biogenesis disorder complementation group K (PBD-CGK); Peroxisome biogenesis disorder 13A (PBD13A)
  • 亞細胞定位:
    Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Peroxin-14 family
  • 數據庫鏈接:

    HGNC: 8856

    OMIM: 601791

    KEGG: hsa:5195

    STRING: 9606.ENSP00000349016

    UniGene: Hs.149983



主站蜘蛛池模板: 狠狠人妻久久久久久综合| 99热在线观看| 国产精品久久久影视青草| 亚洲在线国产日韩欧美| 欧美网站免费观看在线| 国产成人亚洲精品无码最新| 久久一日本综合色鬼综合色| 久久综合亚洲色一区二区三区 | 亚洲精品亚洲人成在线| 2018天天躁夜夜躁狠狠躁| 四虎永久在线精品8848a| 亚洲欧美综合在线天堂| 艳妇乳肉豪妇荡乳xxx| 偷偷要色偷偷中文无码| 亚洲国产精品成人精品无码区| 99er热精品视频| 亚洲国产成人久久一区www| 亚洲日韩精品一区二区三区无码| 精品亚洲成a人片在线观看| 一本加勒比hezyo无码专区| 女子spa高潮呻吟抽搐| 黑人猛挺进小莹的体内视频| 天天做天天爱天天要天天| 欧美巨大黑人精品videos| 中国孕妇变态孕交xxxx| 日本人妻伦在线中文字幕| 一本一本久久a久久综合精品| 真人与拘做受免费视频一| 久久精品国产大片免费观看| 亚洲自偷自偷在线成人网址| 国产成人高清亚洲一区妲妃| 中文字幕人妻无码系列第三区| 国产乱人伦偷精品视频免下载| 四虎亚洲精品高清在线观看| 新香蕉少妇视频网站| 凹凸国产熟女精品视频app| 日韩国产高清一区二区| 精品人妻伦一二三区久久aaa片| 精品亚洲成a人在线观看 | 成人性生交大片免费卡看| 久久久久国产一区二区三区|