在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PEX14 Antibody

  • 中文名稱:
    PEX14兔多克隆抗體
  • 貨號:
    CSB-PA017800GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    PEX14
  • 別名:
    dJ734G22.2 antibody; NAPP2 antibody; NF E2 associated polypeptide 2 antibody; Peroxin 14 antibody; Peroxin-14 antibody; Peroxisomal biogenesis factor 14 antibody; Peroxisomal membrane anchor protein PEX14 antibody; Peroxisomal membrane anchor protein Pex14p antibody; Peroxisomal membrane protein PEX14 antibody; pex14 antibody; PEX14_HUMAN antibody; Pex14p antibody; PTS1 receptor docking protein antibody; PTS1 receptor-docking protein antibody
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human PEX14
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
  • 基因功能參考文獻:
    1. data reveal subpopulations of peroxisomes showing only weak colocalization between PEX14 and PEX5 or PEX11 but at the same time a clear compartmentalized organization. This compartmentalization, which was less evident in cases of strong colocalization, indicates dynamic protein reorganization linked to changes occurring in the peroxisomes. PMID: 27311714
    2. PEX14 is the 13th PEX gene responsible for peroxisome biogenesis disorders. Thus far, only two patients with PEX14 deficiency have been reported. PMID: 26627464
    3. The novel Pex14-binding site may represent the initial tethering site of Pex5 from which the cargo-loaded receptor is further processed in a sequential manner. PMID: 24235149
    4. interaction of PEX5 with catalase and PEX14 PMID: 21976670
    5. PEX14 is a multi-tasking protein that not only facilitates peroxisomal protein import but is also required for peroxisome motility by serving as membrane anchor for microtubules. PMID: 21525035
    6. Serves as a transcriptional corepressor in addition to its peroxisomal function. PMID: 11863372
    7. peroxisomal localization of Pex14p is affected by Pex13p PMID: 14715663
    8. a new complementation group of the peroxisome biogenesis disorders with PEX14 as the defective gene PMID: 15146459
    9. This report represents the second PEX14-deficiency associated with Zellweger syndrome and the first documentation of a PEX14-deficient patient with detailed clinical follow-up and biochemical, morphological, and radiological data. PMID: 18285423
    10. N-terminal domain of Pex14, Pex14(N), adopts a three-helical fold. Pex5 and Pex19 ligand helices bind competitively to the same surface in Pex14(N) albeit with opposite directionality. PMID: 19197237
    11. analysis of the human Pex5.Pex14.PTS1 protein complex structure obtained by small angle X-ray scattering PMID: 19584060

    顯示更多

    收起更多

  • 相關疾病:
    Peroxisome biogenesis disorder complementation group K (PBD-CGK); Peroxisome biogenesis disorder 13A (PBD13A)
  • 亞細胞定位:
    Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Peroxin-14 family
  • 數據庫鏈接:

    HGNC: 8856

    OMIM: 601791

    KEGG: hsa:5195

    STRING: 9606.ENSP00000349016

    UniGene: Hs.149983



主站蜘蛛池模板: 久久国产精品免费一区二区三区| 国产亚洲精品欧洲在线观看| 人妻少妇av中文字幕乱码| 国产欧美久久一区二区 | 久久免费看少妇高潮v片特黄| 色欲综合一区二区三区| 亚洲色偷偷色噜噜狠狠99网| 免费裸体黄网站18禁免费| 无码av在线一本无码| 开心五月激情综合婷婷色| 亚洲精品成人久久久| 成人亚洲欧美在线观看| 2021年精品国产福利在线| 超碰aⅴ人人做人人爽欧美| √天堂资源地址中文在线| 色欲天天网站欧美成人福利网| 好紧好爽好深再快点av在线| 亚洲永久无码7777kkk| 无码人妻一区二区三区免费| 在线日产精品一区| 护士av无码在线观看| 中文字幕乱码熟女人妻水蜜桃| 亚欧美无遮挡hd高清在线视频| 欧美日韩不卡高清在线看| 中文字幕人妻熟在线影院| 最近免费中文字幕mv在线视频3| 天天做天天躁天天躁| 中文av伊人av无码av狼人| 国精一二二产品无人区免费应用| 又大又粗欧美黑人aaaaa片| 国产色在线 | 国产| 日本一道高清一区二区三区| 国产 | 久你欧洲野花视频欧洲1| 欧美黑人性暴力猛交喷水黑人巨大| 亚洲欧美综合精品久久成人网| 无码人妻精品一区二区三区蜜桃| 国产精品vr专区| 超级碰97直线国产免费公开| 中文人妻av大区中文不卡| 亚洲国产av天码精品果冻传媒| 丰满护士巨好爽好大乳|