在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDLIM1 Antibody

PDLIM1 Antibody

  • 中文名稱：
    PDLIM1兔多克隆抗體
  • 貨號：
    CSB-PA017731GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PDLIM1
  • 別名：
    C terminal LIM domain protein 1 antibody; C-terminal LIM domain protein 1 antibody; Carboxy terminal LIM domain protein 1 antibody; CLIM 1 antibody; CLIM1 antibody; CLP 36 antibody; CLP36 antibody; Elfin antibody; Enigma antibody; Enigma homolog antibody; hCLIM 1 antibody; hCLIM1 antibody; LIM domain protein CLP 36 antibody; LIM domain protein CLP-36 antibody; LIM domain protein CLP36 antibody; PDLI1_HUMAN antibody; PDLIM 1 antibody; Pdlim1 antibody; PDZ and LIM domain 1 antibody; PDZ and LIM domain protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PDLIM1,CLP36
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts.
  • 基因功能參考文獻：
    1. PDLIM1 was shown to interact with p75(NTR) in highly invasive patient-derived glioma stem cells/tumor-initiating cells and shRNA knockdown of PDLIM1 in vitro and in vivo results in complete ablation of p75(NTR)-mediated invasion. PMID: 26119933
    2. downregulation of PDLIM1 in colorectal cancer samples correlated with reduced E-cadherin and membrane beta-catenin levels PMID: 26701804
    3. Our results identify CLP36 as an important regulator of breast cancer cell migration and metastasis, and shed light on how increased CLP36 expression contributes to the progression of breast cancer. PMID: 24662836
    4. Femtomolar Zn2+ affinity of LIM domain of PDLIM1 protein uncovers crucial contribution of protein-protein interactions to protein stability. PMID: 22922308
    5. Robust co-regulation of tyrosine phosphorylation sites has been revealed on novel protein interactions between EGFR and PDLIM1. PMID: 22851037
    6. PDLIM1 showed moderate parent-of origin effects for some single nucleotide polymorphisms in attention deficit disorder with hyperactivity. PMID: 21651830
    7. Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies PMID: 21680739
    8. results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers PMID: 11973348
    9. We present evidence for the exclusive protein expression of CLP36 in proliferative and early post-proliferative trophoblast cells. PMID: 16609848
    10. Enigma protein shown to interact with alpha actinin 2 by yeast two-hybrid screening and immunochemistry (co-localization at myocardial Z-disks). PMID: 10861853
    11. CLP-36 contains a PDZ- and LIM domain, is widely expressed, interacts with actinin-1, actinin-2 and actinin-4, and localizes to actin stress fibers. The gene (7 exons) is localised to contig NT_008878.2 on chromosome 10. PMID: 11110697

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
  • 組織特異性：
    Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ov
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2067

    OMIM: 605900

    KEGG: hsa:9124

    STRING: 9606.ENSP00000360305

    UniGene: Hs.368525



主站蜘蛛池模板： 99久久国产热无码精品免费| 97精品国产久热在线观看| 亚洲中文字慕日产2021| 中文无码人妻有码人妻中文字幕| 国产精品一区二区无线| 综合无码一区二区三区| 成人aa免费视频在线播放| 久久亚洲人成综合网| 欧美日本亚洲韩国一区| 99国产欧美另娄久久久精品| 男女啪动最猛动态图| аⅴ天堂中文在线网| 亚洲国产精品无码中文字满| 电影久久久久久| 久久久97丨国产人妻熟女| 成av人片一区二区三区久久 | 精品亚洲国产成人av制服| 精品一区二区三区四区五区六区| 国产精品第一国产精品| 18禁无码永久免费无限制网站| 亚洲手机在线人成网站| 国产欧美va天堂在线观看视频| 成人午夜视频精品一区| 很色很爽很黄裸乳视频| 国内精品久久久久影视老司机| 无遮无挡爽爽免费视频| 美女18禁一区二区三区视频| 國产一二三内射在线看片| 日韩 无码 偷拍 中文字幕| 一二三四视频社区3在线高清| 亚洲偷精品国产五月丁香麻豆| 亚洲bbw性色大片| 精品国产18久久久久久| 青青国产揄拍视频| 九九久久精品国产波多野结衣| 欧美黑人乱大交| www国产亚洲精品久久麻豆| 性国产牲交xxxxx视频| 成人午夜福利视频| 蜜臀av人妻国产精品建身房| 性色av无码中文av有码vr|