在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDLIM1 Antibody

PDLIM1 Antibody

  • 中文名稱：
    PDLIM1兔多克隆抗體
  • 貨號：
    CSB-PA926399
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from Jurkat cells, COLO205 cells, 293 cells, HepG2 cells and HUVEC cells, using PDLIM1 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human heart tissue using PDLIM1 antibody.
    • Immunofluorescence analysis of HepG2 cells, using PDLIM1 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PDLIM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PDLIM1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human PDLIM1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts.
  • 基因功能參考文獻(xiàn)：
    1. PDLIM1 was shown to interact with p75(NTR) in highly invasive patient-derived glioma stem cells/tumor-initiating cells and shRNA knockdown of PDLIM1 in vitro and in vivo results in complete ablation of p75(NTR)-mediated invasion. PMID: 26119933
    2. downregulation of PDLIM1 in colorectal cancer samples correlated with reduced E-cadherin and membrane beta-catenin levels PMID: 26701804
    3. Our results identify CLP36 as an important regulator of breast cancer cell migration and metastasis, and shed light on how increased CLP36 expression contributes to the progression of breast cancer. PMID: 24662836
    4. Femtomolar Zn2+ affinity of LIM domain of PDLIM1 protein uncovers crucial contribution of protein-protein interactions to protein stability. PMID: 22922308
    5. Robust co-regulation of tyrosine phosphorylation sites has been revealed on novel protein interactions between EGFR and PDLIM1. PMID: 22851037
    6. PDLIM1 showed moderate parent-of origin effects for some single nucleotide polymorphisms in attention deficit disorder with hyperactivity. PMID: 21651830
    7. Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies PMID: 21680739
    8. results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers PMID: 11973348
    9. We present evidence for the exclusive protein expression of CLP36 in proliferative and early post-proliferative trophoblast cells. PMID: 16609848
    10. Enigma protein shown to interact with alpha actinin 2 by yeast two-hybrid screening and immunochemistry (co-localization at myocardial Z-disks). PMID: 10861853
    11. CLP-36 contains a PDZ- and LIM domain, is widely expressed, interacts with actinin-1, actinin-2 and actinin-4, and localizes to actin stress fibers. The gene (7 exons) is localised to contig NT_008878.2 on chromosome 10. PMID: 11110697

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
  • 組織特異性：
    Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ov
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2067

    OMIM: 605900

    KEGG: hsa:9124

    STRING: 9606.ENSP00000360305

    UniGene: Hs.368525



主站蜘蛛池模板： 久久精品日日躁夜夜躁欧美| 丰满少妇大叫太大太粗| 真实人与人性恔配视频| 人人妻人人澡人人爽偷拍台湾| 无码av最新高清无码专区| 在线天堂资源www中文| 国产女人高潮毛片| 欧美老熟妇欲乱高清视频 | 免费又黄又爽又猛的毛片| 热99re久久精品这里都是精品免费| 永久免费无码网站在线观看| 久久精品国产亚洲精品| 欧美巨大黑人极品精男| 亚洲久热中文字幕在线| 久久无码高潮喷水抽搐| 免费大香伊蕉在人线国产卡| 色欲狠狠躁天天躁无码中文字幕| 欧美老妇大p毛茸茸| 中文字幕人妻伦伦| 成人影院yy111111在线| 免费女人18毛片a毛片视频 | 日韩少妇内射免费播放18禁裸乳| 国产精品久久久av久久久| 国产欧美日韩综合视频专区| 亚洲国产精品日本无码网站| 国产 日韩 另类 视频一区| 国产综合内射日韩久| 亚洲国产精品无码久久久久高潮| 亚洲精品国产成人精品| 成人网站色52色在线观看| 好了av第四综合无码久久| 久久精品蜜芽亚洲国产av| 久久综合狠狠色综合伊人| 亚洲乱码无人区卡1卡2卡3| 男女性爽大片视频免费看| 国产偷窥熟女精品视频| 妺妺窝人体色www在线下载| 国产午夜三级一区二区三| 成人美女黄网站色大色费全看 | 久久久久久a亚洲欧洲av| 无码高潮喷吹在线观看|