在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDLIM1 Antibody

PDLIM1 Antibody

  • 中文名稱：
    PDLIM1兔多克隆抗體
  • 貨號：
    CSB-PA926399
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from Jurkat cells, COLO205 cells, 293 cells, HepG2 cells and HUVEC cells, using PDLIM1 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human heart tissue using PDLIM1 antibody.
    • Immunofluorescence analysis of HepG2 cells, using PDLIM1 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PDLIM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PDLIM1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human PDLIM1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts.
  • 基因功能參考文獻(xiàn)：
    1. PDLIM1 was shown to interact with p75(NTR) in highly invasive patient-derived glioma stem cells/tumor-initiating cells and shRNA knockdown of PDLIM1 in vitro and in vivo results in complete ablation of p75(NTR)-mediated invasion. PMID: 26119933
    2. downregulation of PDLIM1 in colorectal cancer samples correlated with reduced E-cadherin and membrane beta-catenin levels PMID: 26701804
    3. Our results identify CLP36 as an important regulator of breast cancer cell migration and metastasis, and shed light on how increased CLP36 expression contributes to the progression of breast cancer. PMID: 24662836
    4. Femtomolar Zn2+ affinity of LIM domain of PDLIM1 protein uncovers crucial contribution of protein-protein interactions to protein stability. PMID: 22922308
    5. Robust co-regulation of tyrosine phosphorylation sites has been revealed on novel protein interactions between EGFR and PDLIM1. PMID: 22851037
    6. PDLIM1 showed moderate parent-of origin effects for some single nucleotide polymorphisms in attention deficit disorder with hyperactivity. PMID: 21651830
    7. Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies PMID: 21680739
    8. results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers PMID: 11973348
    9. We present evidence for the exclusive protein expression of CLP36 in proliferative and early post-proliferative trophoblast cells. PMID: 16609848
    10. Enigma protein shown to interact with alpha actinin 2 by yeast two-hybrid screening and immunochemistry (co-localization at myocardial Z-disks). PMID: 10861853
    11. CLP-36 contains a PDZ- and LIM domain, is widely expressed, interacts with actinin-1, actinin-2 and actinin-4, and localizes to actin stress fibers. The gene (7 exons) is localised to contig NT_008878.2 on chromosome 10. PMID: 11110697

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
  • 組織特異性：
    Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ov
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2067

    OMIM: 605900

    KEGG: hsa:9124

    STRING: 9606.ENSP00000360305

    UniGene: Hs.368525



主站蜘蛛池模板： 中国国产1级毛卡片| 亚洲精品天天影视综合网| 亚洲欧美国产双大乳头| 国产免费久久精品99reswag| 国产一区二区三精品久久久无广告| 老熟女五十路乱子交尾中出一区 | 亚洲免费网站观看视频| 在线天堂资源www| 久久香蕉国产线看观看精品yw| 成人影片麻豆国产影片免费观看 | 国产精品人妻一码二码尿失禁| 18禁无码永久免费无限制网站| 18禁裸男晨勃露j毛网站| 少妇高潮太爽了在线视频| 久久精品一区二区三区av| 中文字幕日韩精品亚洲一区| 鲁一鲁一鲁一鲁一曰综合网| 国产精品99久久久久久宅男| 中文在线а天堂中文在线新版| 国产亚洲中文日韩欧美综合网| 欧美性猛少妇xxxxx免费| 亚洲精品nv久久久久久久久久| 午夜裸体性播放| 饥渴丰满少妇大力进入| 亚洲欧美第一成人网站7777| 国产精品亚洲lv粉色| 欧美黑人与白人精品a片| 骚虎成人免费99xx| 亚洲成在人线在线播放无码| 给我免费的视频在线观看| 专干熟肥老妇人视频在线看| 久久天堂av综合合色| 十八禁裸体www网站免费观看| 无码专区 丝袜美腿 制服师生| 无码精品人妻一区二区三区98 | 50岁熟妇大白屁股真爽| 亚洲人成电影在线播放| 8ⅹ8x擦拨擦拨成人免费视频| 亚洲旡码欧美大片| 极品熟妇大蝴蝶20p| 久热在线这里只有精品国产|