在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NOTUM Antibody, HRP conjugated

NOTUM Antibody, HRP conjugated

  • 中文名稱(chēng)：
    NOTUM兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA747435LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) NOTUM Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NOTUM antibody; notum pectinacetylesterase homolog (Drosophila) antibody; Notum pectinacetylesterase homolog antibody; NOTUM_HUMAN antibody; Protein notum homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.
  • 基因功能參考文獻(xiàn)：
    1. NOTUM expression was increased in metastatic cells. Proliferation was suppressed by inhibiting expression of NOTUM. Knockdown of NOTUM genes inhibited proliferation as well as migration, with possible involvement of p38 and c-JUN N-terminal kinase in this process. PMID: 30343282
    2. Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis. PMID: 26517809
    3. Kinetic and mass spectrometric analyses of human proteins show that Notum is a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins and thus constitutes the first known extracellular protein deacylase PMID: 25731175
    4. Overexpression of NOTUM is associated with hepatocellular carcinoma PMID: 18429952
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Pectinacetylesterase family, Notum subfamily
  • 組織特異性：
    Rarely expressed in adult normal tissues.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 27106

    OMIM: 609847

    KEGG: hsa:147111

    STRING: 9606.ENSP00000387310

    UniGene: Hs.106137



主站蜘蛛池模板： 国产成人av大片大片在线播放| 少妇裸交aa大片| 风间由美性色一区二区三区| 人妻中文字幕乱人伦在线| 久久青青草原国产毛片| 久久这里只有是精品23| 久久国国产免费999| 中文字幕无码免费久久99| 一本一本久久a久久精品综合| 国产影片av级毛片特别刺激| 国产精品a久久777777| 久久久久久无码午夜精品直播| 国产亚洲精品a在线无码| 亚洲妇女行蜜桃av网网站| 日产2021免费一区| 无码av免费网站| 西西人体做爰大胆gogo| 老司机久久99久久精品播放免费| 99国产欧美久久久精品| 色偷偷色噜噜狠狠网站久久| 欧美午夜精品久久久久久浪潮| 国产日产欧产美韩系列麻豆| 强行从后面挺进人妻| 绝顶丰满少妇av无码| 亚洲动漫精品无码av天堂| 午夜福利不卡片在线机免费视频| 精品人妻av区波多野结衣| 国产偷人妻精品一区| 天天做av天天爱天天爽| 国产精品人妻一码二码| 国产免费看插插插视频| 女人喷水高潮时的视频网站| 成人免费无码大片a毛片户外 | 天天躁日日躁狠狠躁超碰97| 满春阁精品a∨在线观看| 巨乳美乳一区二区三区| 国产大屁股喷水视频在线观看 | 伊人色合天天久久综合网| 香港三日本8a三级少妇三级99| 国产色在线 | 国产| 亚洲色精品88色婷婷七月丁香|