在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NOTUM Antibody, HRP conjugated

NOTUM Antibody, HRP conjugated

  • 中文名稱(chēng)：
    NOTUM兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA747435LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) NOTUM Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NOTUM antibody; notum pectinacetylesterase homolog (Drosophila) antibody; Notum pectinacetylesterase homolog antibody; NOTUM_HUMAN antibody; Protein notum homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.
  • 基因功能參考文獻(xiàn)：
    1. NOTUM expression was increased in metastatic cells. Proliferation was suppressed by inhibiting expression of NOTUM. Knockdown of NOTUM genes inhibited proliferation as well as migration, with possible involvement of p38 and c-JUN N-terminal kinase in this process. PMID: 30343282
    2. Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis. PMID: 26517809
    3. Kinetic and mass spectrometric analyses of human proteins show that Notum is a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins and thus constitutes the first known extracellular protein deacylase PMID: 25731175
    4. Overexpression of NOTUM is associated with hepatocellular carcinoma PMID: 18429952
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Pectinacetylesterase family, Notum subfamily
  • 組織特異性：
    Rarely expressed in adult normal tissues.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 27106

    OMIM: 609847

    KEGG: hsa:147111

    STRING: 9606.ENSP00000387310

    UniGene: Hs.106137



主站蜘蛛池模板： 久久中文字幕无码a片不卡古代| 精品无码国产一区二区三区51安| 亚洲色无码中文字幕yy51999| 亚洲色www永久网站| 欧美丰满大乳大屁股流白浆| 少妇高潮流白浆在线观看| 成 人 色综合 综合网站| 免费永久在线观看黄网站| 99精品国产福久久久久久| 国产超碰人人爽人人做人人添| 特级无码毛片免费视频尤物 | 窝窝影院午夜看片| 欧美 亚洲 国产 日韩 综aⅴ | 国产免费久久精品99reswag | 黑人大荫蒂老太大| 免费无码av片在线观看| 西西444www大胆无码视频| 最近中文字幕mv在线视频看| 欧美人与牲动交xxxx| 国内最真实的xxxx人伦| 又色又污又爽又黄的网站| 玩弄了裸睡少妇人妻野战| 很黄很黄的曰批视频| 又色又爽又黄的视频软件app | 老司机深夜18禁污污网站| 亚洲国产av导航第一福利网| 亚洲午夜成人片| 99久久精品国产一区二区三区| 国产精品乱子伦xxxx裸| 草草网站影院白丝内射| 国产在线无码一区二区三区视频 | 在线精品自偷自拍无码| 欧美巨大另类极品videosbest| √天堂资源地址在线官网| 国产免费爽爽视频在线观看| 午夜一区二区亚洲福利| 毛片免费视频观看| 亚洲天堂2017无码中文| 亚洲vs成人无码人在线观看堂| 亚洲熟女av乱码在线观看漫画| 国产亚洲婷婷香蕉久久精品|