在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NOTUM Antibody, FITC conjugated

NOTUM Antibody, FITC conjugated

  • 中文名稱：
    NOTUM兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA747435LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NOTUM Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NOTUM antibody; notum pectinacetylesterase homolog (Drosophila) antibody; Notum pectinacetylesterase homolog antibody; NOTUM_HUMAN antibody; Protein notum homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.
  • 基因功能參考文獻：
    1. NOTUM expression was increased in metastatic cells. Proliferation was suppressed by inhibiting expression of NOTUM. Knockdown of NOTUM genes inhibited proliferation as well as migration, with possible involvement of p38 and c-JUN N-terminal kinase in this process. PMID: 30343282
    2. Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis. PMID: 26517809
    3. Kinetic and mass spectrometric analyses of human proteins show that Notum is a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins and thus constitutes the first known extracellular protein deacylase PMID: 25731175
    4. Overexpression of NOTUM is associated with hepatocellular carcinoma PMID: 18429952
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Pectinacetylesterase family, Notum subfamily
  • 組織特異性：
    Rarely expressed in adult normal tissues.
  • 數據庫鏈接：

    HGNC: 27106

    OMIM: 609847

    KEGG: hsa:147111

    STRING: 9606.ENSP00000387310

    UniGene: Hs.106137



主站蜘蛛池模板： 高潮内射免费看片| 国产真人做爰视频免费| 成人无码精品一区二区三区亚洲区| 亚洲精品一卡2卡三卡4卡| 九九综合va免费看| 女人被爽到呻吟gif动态图视看| 无码成a毛片免费| 老太脱裤让老头玩ⅹxxxx | 香港日本三级亚洲三级| 国产乱子伦精品免费无码专区| 亚洲欧美日韩愉拍自拍美利坚| 国产日韩在线视看高清视频手机 | 在线欧美日韩制服国产| 亚拍精品一区二区三区探花| 久热这里只有精品99| 午夜成人亚洲理论片在线观看| 太深太粗太爽太猛了视频免费观看| 亚洲.欧美.在线视频| 四虎影视在线观看2413| 日日摸天天爽天天爽视频| 人妻精品无码一区二区三区| 亚洲精品国产品国语在线观看| 国产成人麻豆精品午夜福利在线 | 国产午夜福利在线播放| 久99久无码精品视频免费播放| 国产成av人片在线观看天堂无码| 亚洲第一狼人天堂久久| 无码人妻一区二区三区免费n鬼逝| 欧美成人www免费全部网站| 野外亲子乱子伦视频丶 | 国产成人精品高清在线观看93| 国产乱人伦偷精精品视频| 久久婷婷五月综合色国产| 国产午夜精品无码| 亚洲性色av一区二区三区| 四房播色综合久久婷婷| 国产亚洲精品久久久久9999| 久久久久欧美精品观看| 正在播放国产真实露脸高清| 22222se男人的天堂| 天堂中文最新版在线官网在线|