在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NOTUM Antibody, FITC conjugated

NOTUM Antibody, FITC conjugated

  • 中文名稱：
    NOTUM兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA747435LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NOTUM Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NOTUM antibody; notum pectinacetylesterase homolog (Drosophila) antibody; Notum pectinacetylesterase homolog antibody; NOTUM_HUMAN antibody; Protein notum homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.
  • 基因功能參考文獻：
    1. NOTUM expression was increased in metastatic cells. Proliferation was suppressed by inhibiting expression of NOTUM. Knockdown of NOTUM genes inhibited proliferation as well as migration, with possible involvement of p38 and c-JUN N-terminal kinase in this process. PMID: 30343282
    2. Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis. PMID: 26517809
    3. Kinetic and mass spectrometric analyses of human proteins show that Notum is a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins and thus constitutes the first known extracellular protein deacylase PMID: 25731175
    4. Overexpression of NOTUM is associated with hepatocellular carcinoma PMID: 18429952
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Pectinacetylesterase family, Notum subfamily
  • 組織特異性：
    Rarely expressed in adult normal tissues.
  • 數據庫鏈接：

    HGNC: 27106

    OMIM: 609847

    KEGG: hsa:147111

    STRING: 9606.ENSP00000387310

    UniGene: Hs.106137



主站蜘蛛池模板： 亚洲人成网线在线播放| 免费吃奶摸下激烈视频| 天天躁夜夜躁狠狠眼泪| 国产精品久久婷婷六月丁香| 国产超碰人人做人人爽av| 亚洲国产欧美在线人成aaaa| 久久精品无码精品免费专区| 国产成人精品高清在线观看99| 性色高清xxxxx厕所偷窥| 五月天天天综合精品无码| 丰满少妇69激情啪啪无| 少妇下蹲露大唇无遮挡| 天天做av天天爱天天爽| 国产片av片永久免费观看| 亚洲精品成人网站在线观看| 非洲人与性动交ccoo| 在线成人a毛片免费播放 | 国产内射999视频一区| 亚洲中文有码字幕青青| 成人国产精品一区二区免费看 | 思思99热久久精品在线6| 精品少妇人妻av无码久久| 亚洲欧美韩国综合色| 亚洲精品第一国产综合国服瑶| 国产偷v国产偷v亚洲高清| 国产精品交换| 18禁无遮挡羞羞污污污污免费| 美女18禁一区二区三区视频| 日本中文字幕有码在线视频| 国产激情大臿免费视频| 久久人人做人人爽人人av| 久久精品国产精品亚洲艾草网| 婷婷国产成人精品视频| 人妻人人澡人人添人人爽人人玩 | 国产性天天综合网| 国产熟妇搡bbbb搡bbbb| 午夜福利18以下勿进免费| 久久人人做人人妻人人玩精品va| 97精品久久久久中文字幕| 婷婷五月日韩av永久免费| 亚洲精品久久久久一区二区三区|