在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NEFM Antibody

  • 中文名稱:
    NEFM兔多克隆抗體
  • 貨號:
    CSB-PA298176
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA298176(NEFM Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA298176(NEFM Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minutes
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    NEFM
  • 別名:
    150kDa medium antibody; 160 kDa neurofilament protein antibody; 2 kDa neurofilament protein antibody; 200 kDa neurofilament protein antibody; 68 kDa neurofilament protein antibody; AI847934 antibody; CMT1F antibody; CMT2CC antibody; CMT2E antibody; FLJ53642 antibody; KIAA0845 antibody; light molecular weight neurofilament protein antibody; Micro glutamic acid-rich protein antibody; mKIAA0845 antibody; Nef3 antibody; NEFH antibody; NEFL antibody; NEFM antibody; Neurofilament 3 antibody; Neurofilament heavy polypeptide 200kDa antibody; Neurofilament heavy polypeptide antibody; Neurofilament light polypeptide 68kDa antibody; Neurofilament light polypeptide antibody; Neurofilament medium polypeptide 150kDa antibody; Neurofilament medium polypeptide antibody; Neurofilament protein heavy polypeptide antibody; Neurofilament protein light chain antibody; Neurofilament protein light polypeptide antibody; Neurofilament protein medium polypeptide antibody; neurofilament subunit NF-L antibody; Neurofilament triplet H protein antibody; Neurofilament triplet L protein antibody; Neurofilament triplet M protein antibody; neurofilament-3 (150 kD medium) antibody; NF-H antibody; NF-L antibody; NF-M antibody; NF160 antibody; NF165 antibody; NF200 antibody; NF68 antibody; NFH antibody; NFL antibody; NFM antibody; NFM_HUMAN antibody; PPP1R110 antibody; protein phosphatase 1, regulatory subunit 110 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human NEFM
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks.
  • 基因功能參考文獻:
    1. Study determined that spinophilin binding to neurofilament medium required overexpression of the catalytic subunit of protein kinase A and was decreased by cyclin-dependent protein kinase 5. PMID: 28634551
    2. NEFM is a negative regulator of aldosterone production and cell proliferation, in part by facilitating D1R internalization from the plasma membrane in Adosterone-producing Adenomas. PMID: 28584012
    3. There was a strongly elevated reactivity against neurofilament medium in a subset of schizophrenia patients compared to controls. PMID: 24636402
    4. direct evidence that NF-M/H are hyperphosphorylated in Alzheimer disease PMID: 20624930
    5. the importance of alpha-internexin and NF-L in regulating the conformations of NF-M and NF-H PMID: 20213320
    6. This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia PMID: 20381070
    7. To study if the increase of levels of neurofilament (NF)-M and NF-L in brain of Alzheimer's diseases (AD) is caused by increase of NF-M and NF-L. PMID: 12133495
    8. Two polymorphisms of neurofilament M(Ala475Thr and Gly697Arg) occurred at similar frequencies in PD patients and controls. A Pro725Gln substitution and a deletion of valine in position 829 were identified in two PD patients. PMID: 14583397
    9. The G336S variant of hNF-M does not affect the formation of IF networks nor the distribution of the variant hNFM protein. If the G336S variant is involved in the development of PD, it isn't due to defects in the assembly and distribution of NFs. PMID: 15290901
    10. O-glycosylation of NF-M is highly dynamic and closely interwoven with phosphorylation cascades and may have a pathophysiological role. PMID: 16006557
    11. mutations in neurofilaments are possible risk factors that may contribute to pathogenesis in amytrophic lateral sclerosis in conjunction with one or more additional genetic or environmental factors, but are not significant primary causes PMID: 16084104
    12. variation in NEF3 influence rate of response to typical antipsychotic medication PMID: 16734940

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection, axon.
  • 蛋白家族:
    Intermediate filament family
  • 數據庫鏈接:

    HGNC: 7734

    OMIM: 162250

    KEGG: hsa:4741

    STRING: 9606.ENSP00000221166

    UniGene: Hs.458657



主站蜘蛛池模板: 国产精品扒开腿做爽爽爽视频| 天堂资源中文| 吸咬奶头狂揉60分钟视频| 中文在线а√在线| 国产成人无码av片在线观看不卡| 少妇人妻挤奶水中文视频毛片| 亚洲精品国偷拍自产在线麻豆| 婷婷四房播播| 少妇午夜福利一区二区| 97超碰中文字幕久久精品 | 人妻内射一区二区在线视频| 国产精品原创巨作av女教师| 无码人妻丝袜在线视频红杏| 亚洲精品国偷拍自产在线观看蜜桃| 波多野结衣美乳人妻hd电影欧美| 精品无码综合一区二区三区| 成人h无码动漫超w网站| 国产成年无码v片在线| 无码人妻久久一区二区三区蜜桃 | 婷婷综合久久中文字幕| 欧美性生交大片18禁止| 影音先锋人妻av中文字幕久久| 丰满少妇夜夜爽爽高潮水 | 日本又黄又爽gif动态图| 五月丁香六月综合缴清无码 | 国产精品sm捆绑调教视频| 久久久久亚洲国产av麻豆| 国产999精品成人网站| 九九九国产精品成人免费视频| 精品久久久久久亚洲中文字幕| 国产裸体舞一区二区三区| 久久国产劲爆∧v内射-百度| 国产亚洲精品无码不卡| 免费看又色又爽又黄的国产软件| 久久亚洲一区二区三区四区| 亚洲aⅴ无码专区在线观看| 久久综合亚洲欧美成人| 亚洲亚洲人成综合网络| 国产蝌蚪视频一区二区三区| 亚洲性av网站| 亚洲国产精品热久久|