在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NEFM Antibody

  • 中文名稱:
    NEFM兔多克隆抗體
  • 貨號:
    CSB-PA298176
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA298176(NEFM Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA298176(NEFM Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minutes
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    NEFM
  • 別名:
    150kDa medium antibody; 160 kDa neurofilament protein antibody; 2 kDa neurofilament protein antibody; 200 kDa neurofilament protein antibody; 68 kDa neurofilament protein antibody; AI847934 antibody; CMT1F antibody; CMT2CC antibody; CMT2E antibody; FLJ53642 antibody; KIAA0845 antibody; light molecular weight neurofilament protein antibody; Micro glutamic acid-rich protein antibody; mKIAA0845 antibody; Nef3 antibody; NEFH antibody; NEFL antibody; NEFM antibody; Neurofilament 3 antibody; Neurofilament heavy polypeptide 200kDa antibody; Neurofilament heavy polypeptide antibody; Neurofilament light polypeptide 68kDa antibody; Neurofilament light polypeptide antibody; Neurofilament medium polypeptide 150kDa antibody; Neurofilament medium polypeptide antibody; Neurofilament protein heavy polypeptide antibody; Neurofilament protein light chain antibody; Neurofilament protein light polypeptide antibody; Neurofilament protein medium polypeptide antibody; neurofilament subunit NF-L antibody; Neurofilament triplet H protein antibody; Neurofilament triplet L protein antibody; Neurofilament triplet M protein antibody; neurofilament-3 (150 kD medium) antibody; NF-H antibody; NF-L antibody; NF-M antibody; NF160 antibody; NF165 antibody; NF200 antibody; NF68 antibody; NFH antibody; NFL antibody; NFM antibody; NFM_HUMAN antibody; PPP1R110 antibody; protein phosphatase 1, regulatory subunit 110 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human NEFM
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks.
  • 基因功能參考文獻:
    1. Study determined that spinophilin binding to neurofilament medium required overexpression of the catalytic subunit of protein kinase A and was decreased by cyclin-dependent protein kinase 5. PMID: 28634551
    2. NEFM is a negative regulator of aldosterone production and cell proliferation, in part by facilitating D1R internalization from the plasma membrane in Adosterone-producing Adenomas. PMID: 28584012
    3. There was a strongly elevated reactivity against neurofilament medium in a subset of schizophrenia patients compared to controls. PMID: 24636402
    4. direct evidence that NF-M/H are hyperphosphorylated in Alzheimer disease PMID: 20624930
    5. the importance of alpha-internexin and NF-L in regulating the conformations of NF-M and NF-H PMID: 20213320
    6. This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia PMID: 20381070
    7. To study if the increase of levels of neurofilament (NF)-M and NF-L in brain of Alzheimer's diseases (AD) is caused by increase of NF-M and NF-L. PMID: 12133495
    8. Two polymorphisms of neurofilament M(Ala475Thr and Gly697Arg) occurred at similar frequencies in PD patients and controls. A Pro725Gln substitution and a deletion of valine in position 829 were identified in two PD patients. PMID: 14583397
    9. The G336S variant of hNF-M does not affect the formation of IF networks nor the distribution of the variant hNFM protein. If the G336S variant is involved in the development of PD, it isn't due to defects in the assembly and distribution of NFs. PMID: 15290901
    10. O-glycosylation of NF-M is highly dynamic and closely interwoven with phosphorylation cascades and may have a pathophysiological role. PMID: 16006557
    11. mutations in neurofilaments are possible risk factors that may contribute to pathogenesis in amytrophic lateral sclerosis in conjunction with one or more additional genetic or environmental factors, but are not significant primary causes PMID: 16084104
    12. variation in NEF3 influence rate of response to typical antipsychotic medication PMID: 16734940

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection, axon.
  • 蛋白家族:
    Intermediate filament family
  • 數據庫鏈接:

    HGNC: 7734

    OMIM: 162250

    KEGG: hsa:4741

    STRING: 9606.ENSP00000221166

    UniGene: Hs.458657



主站蜘蛛池模板: 中文字幕无线码| 日本熟妇乱人伦a片免费高清| 99久久久无码国产精品不卡| 精品人妻少妇一区二区三区不卡| 国产成人a区在线观看| 亚洲欧洲无卡二区视頻| 性男女做视频观看网站| 亚洲乱码伦小说区| 99久久精品无码一区二区三区| 久久国产精品精品国产色婷婷| 中文字幕av高清片| 亚洲国产欧美在线看片一国产 | 国产精品亚洲片在线观看不卡 | 国产女人18毛片水真多1| 国产内射999视频一区| 亚洲熟妇久久国内精品| 国内少妇偷人精品视频| 国产sm重味一区二区三区| 国产乱子伦一区二区三区| 强被迫伦姧惨叫人妻系列| h人成在线看免费视频| 永久免费不卡在线观看黄网站 | 熟女少妇丰满一区二区| 亚洲成av人片一区二区密柚| 人人玩人人添人人澡| 亚洲中字慕日产2020| 国产一性一交一伦一a片| 欧美又粗又长又爽做受| 新普新京亚洲欧美日韩国产| 区二区三区国产精华液区别大吗| 无码超乳爆乳中文字幕| 久无码久无码av无码| 成人欧美一区二区三区a片| 四库影院永久四虎精品国产| 日韩精品人成在线播放| 99久久精品美女高潮喷水| 久久99国产综合精品女同| av 日韩 人妻 黑人 综合 无码| 日本内射精品一区二区视频| 色噜噜亚洲男人的天堂| 日本免费一区二区三区四区五区 |