在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MTMR6 Antibody

MTMR6 Antibody

  • 中文名稱：
    MTMR6兔多克隆抗體
  • 貨號：
    CSB-PA897519LA01HU
  • 規格：
    ￥440
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MTMR6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    4022440C11Rik antibody; AI428804 antibody; AU041072 antibody; MGC27983 antibody; MTMR 6 antibody; Mtmr6 antibody; MTMR6_HUMAN antibody; Myotubularin related protein 6 antibody; Myotubularin-related protein 6 antibody; RP11-271M24.1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Myotubularin-related protein 6 protein (1-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，MTMR6 Antibody (CSB-PA897519LA01HU)，的標記方式是Non-conjugated。對于MTMR6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA897519LB01HU MTMR6 Antibody, HRP conjugated ELISA
    FITC CSB-PA897519LC01HU MTMR6 Antibody, FITC conjugated
    Biotin CSB-PA897519LD01HU MTMR6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphatase that acts on lipids with a phosphoinositol headgroup. Dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,5-bisphosphate (Probable). Binds with high affinity to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) but also to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), phosphatidic acid and phosphatidylserine. Negatively regulates ER-Golgi protein transport. Probably in association with MTMR9, plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3-phosphate in membrane ruffles. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4(+) T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3-phosphate. Negatively regulates proliferation of reactivated CD4(+) T-cells. In complex with MTMR9, negatively regulates DNA damage-induced apoptosis. The formation of the MTMR6-MTMR9 complex stabilizes both MTMR6 and MTMR9 protein levels.
  • 基因功能參考文獻：
    1. MTMR6, which dephosphorylates PI(3)P to PI, and its binding partner MTMR9, are required for macropinocytosis. PMID: 24591580
    2. results indicate that the cellular localization of MTMR6 is regulated by Rab1B in the early secretory and autophagic pathways PMID: 23188820
    3. investigation of MTM1 and MTMR6 and finding that they use PtdIns(3,5)P2 in addition to PtdIns3P as a substrate in vitro PMID: 12646134
    4. Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP. PMID: 12847286
    5. Data show that KCa3.1, which is critical for Ca2+ influx in reactivated naive T cells and central memory T cells, requires phosphatidylinositol-3 phosphatase for activation and is inhibited by PI(3)P phosphatase myotubularin-related protein 6 (MTMR6). PMID: 16847315
    6. MTMR9 greatly enhances the functions of MTMR6 PMID: 19038970

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
  • 組織特異性：
    Expressed in CD4+ T-cells.
  • 數據庫鏈接：

    HGNC: 7453

    OMIM: 603561

    KEGG: hsa:9107

    STRING: 9606.ENSP00000371221

    UniGene: Hs.643702



主站蜘蛛池模板： 日本熟妇色一本在线观看| 国产精品户外野外| 99久久久无码国产精品免费| 国产人妻人伦精品1国产丝袜| 无码精品国产dvd在线观看9久| 97se亚洲综合自在线| 最新国产麻豆aⅴ精品无码| 亚洲 中文字幕 日韩 无码| 国产午夜精品理论片| 亚洲国产精品日本无码网站| 亚洲精品美女久久777777| 亚洲春色在线视频| 久99久无码精品视频免费播放| 亚洲午夜成人久久久久久 | 97精品免费公开在线视频| 久久大香国产成人av| 久久久久九九精品影院| 欧美成人一区二区三区| 亚洲欧洲自拍拍偷精品网| 国产日产欧产精品品不卡| 女人被男人爽到呻吟的视频| 成人国产网站v片免费观看| 国产成人精品午夜视频| 国产精品青草久久久久福利99| 理论片午午伦夜理片影院99| 午夜福利视频合集1000| 色综久久综合桃花网国产精品| 大香伊人久久精品一区二区| 麻豆av一区二区天美传媒| 国产成人午夜福利在线播放| 国产亚洲精品一区二三区| 中文字幕久久熟女人妻av免费 | 综合亚洲伊人午夜网| www片香蕉内射在线88av8| 18禁区美女免费观看网站| 狠狠噜天天噜日日噜视频麻豆 | 男女吃奶做爰猛烈紧视频| 国产在线午夜不卡精品影院| 国产精品扒开腿做爽爽爽a片唱戏| 四虎影成人精品a片| 成 人 亚洲 综合天堂|