在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MTMR3 Antibody, HRP conjugated

MTMR3 Antibody, HRP conjugated

  • 中文名稱：
    MTMR3兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA622675HB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MTMR3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    FYVE domain-containing dual specificity protein phosphatase 1 antibody; FYVE-DSP1 antibody; MTMR3 antibody; MTMR3_HUMAN antibody; Myotubularin-related protein 3 antibody; Zinc finger FYVE domain-containing protein 10 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Myotubularin-related protein 3 protein (652-899AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest MTMR3 has multiple functions in regulation of autophagy; one mechanism appears to be direct interaction between MTMR3 and mTORC1 (MTOR, mLST8, raptor) which inhibits phosphorylation activity of mTORC1; MTMR3 is localized to Golgi apparatus. PMID: 26787466
    2. the rs713875 IBD risk polymorphism increases MTMR3 expression, which modulates pattern recognition receptor (PRR)-induced outcomes, including increased induced caspase-1 activation PMID: 26240347
    3. myotubularin-related protein 3 and myotubularin-related protein 4 may act as a bridge between CEP55 and polo-like kinase 1, ensuring proper CEP55 phosphorylation and regulating CEP55 recruitment to the midbody. PMID: 25659891
    4. cloning, expression, purification and crystallization of human myotubularin-related protein 3 encompassing the PH-GRAM and the phosphatase catalytic domain are reported PMID: 25195900
    5. These results indicate that MTMR3 may play an important role in the progression of CRC and suggest that siRNA mediated silencing of MTMR3 could be an effective tool in CRC treatment. PMID: 25215329
    6. Our results suggest that the MTMR3 gene is shared between IgA nephropathy and lupus nephritis in the northern Chinese population, further highlighting the role of autophagy in systemic lupus erythematosus. PMID: 24943867
    7. Data suggest MTMR3, PIKFYVE (phosphoinositide kinase FYVE), and their product phosphatidylinositol 5-phosphate are involved in activation of RAC1 (rho family small GTP binding protein); this process regulates migration/invasion of carcinoma/sarcoma. PMID: 24840251
    8. Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration. PMID: 23154468
    9. MTMR3 belongs to the myotubularin family of phosphoinositides phosphatases PMID: 9736772
    10. MTMR3 shares similar phosphatase activity and substrate specificity with its homologous proteins MTM1 and MTMR3 PMID: 11846405
    11. A phylogenetic study revealing co-evolution of myotubularins with PI 3-kinase class III complex PMID: 18774718
    12. Autophagosome formation was triggered by the overexpression of a dominant-negative inactive mutant of Myotubularin-related phosphatase 3 (MTMR3). PMID: 20059746
    13. analysis of MTMR3 phosphoinositide binding domain properties PMID: 15840652

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 7451

    OMIM: 603558

    KEGG: hsa:8897

    STRING: 9606.ENSP00000384651

    UniGene: Hs.474536



主站蜘蛛池模板： 亚洲图欧洲图自拍另类高清| 色综合久久中文娱乐网| 久久视频这里只精品| av无码人妻波多野结衣| 午夜福利啪啪片| 中国女人内谢69xxxxxa片| 男人扒女人添高潮视频| 在线涩涩免费观看国产精品| 欧美黑人又粗又大xxx| 少妇一晚三次一区二区三区| 国产情侣久久久久aⅴ免费| 欧美gv在线观看| 在线观看潮喷失禁大喷水无码| 久久久久人妻一区精品果冻| 再深点灬舒服灬太大了网站| 狠狠干狠狠爱| 狠狠色噜噜狠狠狠888777米奇| 欧美成人精品一区二区三区色欲| 免费看成人啪啪| 亚洲va久久久噜噜噜久久4399 | 亚洲成a人片在线观看天堂无码| 精品国产乱码久久久久久1区2区 | 国产精品 自在自线| 亚洲一本一道一区二区三区| 色婷婷欧美在线播放内射| 国产成人亚洲精品| 免费毛片手机在线播放| 国产性色播播毛片| 无码少妇一区二区| 亚洲综合色婷婷七月丁香| 国产精品va无码二区| 国产熟妇按摩3p高潮大叫| 欧美熟妇性开放| 日韩免费无码视频一区二区三区| 国产精品久久久久久久久久直播 | 四虎成人精品无码永久在线| 720lu国产刺激无码| 特黄特色大片免费播放器图片| 老湿机69福利区无码| 久久综合a∨色老头免费观看| 亚洲精品中国国产嫩草影院美女|