在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MTMR3 Antibody, FITC conjugated

MTMR3 Antibody, FITC conjugated

  • 中文名稱：
    MTMR3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA622675HC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MTMR3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    FYVE domain-containing dual specificity protein phosphatase 1 antibody; FYVE-DSP1 antibody; MTMR3 antibody; MTMR3_HUMAN antibody; Myotubularin-related protein 3 antibody; Zinc finger FYVE domain-containing protein 10 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Myotubularin-related protein 3 protein (652-899AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues.
  • 基因功能參考文獻：
    1. Data suggest MTMR3 has multiple functions in regulation of autophagy; one mechanism appears to be direct interaction between MTMR3 and mTORC1 (MTOR, mLST8, raptor) which inhibits phosphorylation activity of mTORC1; MTMR3 is localized to Golgi apparatus. PMID: 26787466
    2. the rs713875 IBD risk polymorphism increases MTMR3 expression, which modulates pattern recognition receptor (PRR)-induced outcomes, including increased induced caspase-1 activation PMID: 26240347
    3. myotubularin-related protein 3 and myotubularin-related protein 4 may act as a bridge between CEP55 and polo-like kinase 1, ensuring proper CEP55 phosphorylation and regulating CEP55 recruitment to the midbody. PMID: 25659891
    4. cloning, expression, purification and crystallization of human myotubularin-related protein 3 encompassing the PH-GRAM and the phosphatase catalytic domain are reported PMID: 25195900
    5. These results indicate that MTMR3 may play an important role in the progression of CRC and suggest that siRNA mediated silencing of MTMR3 could be an effective tool in CRC treatment. PMID: 25215329
    6. Our results suggest that the MTMR3 gene is shared between IgA nephropathy and lupus nephritis in the northern Chinese population, further highlighting the role of autophagy in systemic lupus erythematosus. PMID: 24943867
    7. Data suggest MTMR3, PIKFYVE (phosphoinositide kinase FYVE), and their product phosphatidylinositol 5-phosphate are involved in activation of RAC1 (rho family small GTP binding protein); this process regulates migration/invasion of carcinoma/sarcoma. PMID: 24840251
    8. Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration. PMID: 23154468
    9. MTMR3 belongs to the myotubularin family of phosphoinositides phosphatases PMID: 9736772
    10. MTMR3 shares similar phosphatase activity and substrate specificity with its homologous proteins MTM1 and MTMR3 PMID: 11846405
    11. A phylogenetic study revealing co-evolution of myotubularins with PI 3-kinase class III complex PMID: 18774718
    12. Autophagosome formation was triggered by the overexpression of a dominant-negative inactive mutant of Myotubularin-related phosphatase 3 (MTMR3). PMID: 20059746
    13. analysis of MTMR3 phosphoinositide binding domain properties PMID: 15840652

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
  • 數據庫鏈接：

    HGNC: 7451

    OMIM: 603558

    KEGG: hsa:8897

    STRING: 9606.ENSP00000384651

    UniGene: Hs.474536



主站蜘蛛池模板： 亚洲最大成人一区久久久| 小妖精又紧又湿高潮h视频69| 熟女人妻水多爽中文字幕| 无码纯肉动漫在线观看| 邻居少妇张开腿让我爽了一夜 | 日本高清二区视频久二区| 老熟妇性老熟妇性色| 日韩在线不卡免费视频一区| 熟女人妻大叫粗大受不了| 高潮喷水无码av亚洲| 97久久超碰精品视觉盛宴| 亚洲の无码国产の无码步美| 久久久久女教师免费一区| 97se亚洲国产综合自在线尤物| 国产人妻xxxx精品hd| 无码人妻一区二区三区av| 中文在线а√天堂| 午夜a理论片在线播放| av无码国产在线看免费网站| 自拍偷自拍亚洲精品播放| 国产精品a成v人在线播放| 翘臀后进少妇大白嫩屁股| 日韩视频 中文字幕 视频一区| 久久天天躁狠狠躁夜夜avapp| 少妇无码av无码专区线| 久久青草成人综合网站| 国产真人做爰视频免费| 亚洲熟妇av日韩熟妇在线 | 欧洲亚洲色一区二区色99| 免费国产午夜理论片不卡| 日本高清二区视频久二区| 色狠狠色狠狠综合天天| 天天燥日日燥| 亚洲爆乳成av人在线蜜芽| 亚洲伊人成综合网| 国产成人精品日本亚洲77上位| 久久国产乱子伦精品免费女人| 国产成人精品免费午夜app| 中文字幕色av一区二区三区| 天天操夜夜操| 午夜伦4480yy私人影院久久|