在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MIA3 Antibody

MIA3 Antibody

  • 中文名稱：
    MIA3兔多克隆抗體
  • 貨號：
    CSB-PA711448LA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MIA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MIA3
  • 別名：
    ARNT antibody; C219 reactive peptide antibody; C219-reactive peptide antibody; D320 antibody; Melanoma inhibitory activity family; member 3 antibody; Melanoma inhibitory activity protein 3 antibody; Mia3 antibody; MIA3_HUMAN antibody; RP11-378J18.4 antibody; TANGO antibody; Transport and Golgi organization protein 1 antibody; UNQ6077 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transport and Golgi organization protein 1 homolog protein (1447-1626AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，MIA3 Antibody (CSB-PA711448LA01HU)，的標記方式是Non-conjugated。對于MIA3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA711448LB01HU MIA3 Antibody, HRP conjugated ELISA
    FITC CSB-PA711448LC01HU MIA3 Antibody, FITC conjugated
    Biotin CSB-PA711448LD01HU MIA3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum. Required for correct assembly of COPII coat components at endoplasmic reticulum exit sites (ERES) and for the localization of SEC16A and membrane-bound ER-resident complexes consisting of MIA2 and PREB/SEC12 to ERES.
  • 基因功能參考文獻：
    1. ADTRP positively regulates PIK3R3 expression, which leads to activation of AKT and up-regulation of MIA3/TANGO1, thereby regulating endothelial cell functions directly relevant to atherosclerosis. PMID: 28341552
    2. TANGO1/CTAGE5 receptor serves as a polyvalent template for assembly of large COPII coats. PMID: 27551091
    3. Mammalian endoplasmic reticulum exit sites are organized by TANGO1 acting as a scaffold, in cooperation with Sec16 for efficient secretion. PMID: 28442536
    4. TANGO1 is thus pivotal in concentrating procollagen VII in the lumen and recruiting ERGIC membranes on the cytoplasmic surface of the endoplasmic reticulum. PMID: 26568311
    5. TANGO expression was strongly associated with tumour progression, nodal metastasis, clinical stage and number of blood or lymph vessels in oral squamous cell carcinoma. PMID: 24889917
    6. We conclude that SNP rs17465637 in MIA3 is indeed a genetic risk factor for CAD across different ethnic populations including Han Chinese. PMID: 24125424
    7. results suggest a potential association of the MIA3 rs17465637 with cardiovascular disease in dyslipidemic patients with rheumatoid arthritis PMID: 22577832
    8. genetic polymorphism is associated with an increased risk of myocardial infarction PMID: 21264445
    9. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20738937
    10. Observational study of gene-disease association. (HuGE Navigator) PMID: 20971364
    11. Observational study of gene-disease association. (HuGE Navigator) PMID: 20694560
    12. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    13. TANGO transfected cell lines revealed that TANGO expression reduces motility, whereas reduction of TANGO enhances migration. PMID: 17044017
    14. The results from this study present TANGO as a novel ligand for CD11c, regulating migratory processes of hematopoietic cells. PMID: 17726152
    15. Reduced expression of TANGO is associated with colon and hepatocellular carcinomas PMID: 17786351
    16. Observational study of gene-disease association. (HuGE Navigator) PMID: 19955471
    17. Observational study of gene-disease association. (HuGE Navigator) PMID: 19336575
    18. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19198609

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    MIA/OTOR family, Tango1 subfamily
  • 組織特異性：
    Broadly expressed, except in bone marrow and peripheral blood mononuclear cells. Down-regulated in melanoma tissue.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24008

    OMIM: 613455

    KEGG: hsa:375056

    STRING: 9606.ENSP00000340900

    UniGene: Hs.118474



主站蜘蛛池模板： 精品麻豆国产色欲色欲色欲www| 黄网站免费永久在线观看下载| 亚洲国产成人精品无码区花野真一| 综合色一色综合久久网| 亚洲成a人片在线观看天堂无码不卡| 4hu亚洲人成人无码网www电影首页 | 免费国产成人高清在线观看网站| 韩国精品久久久久久无码| 久久久综合九色合综| 免费国产黄网站在线观看| 18禁裸乳无遮挡啪啪无码免费| 欧美性黑人极品hd另类| 最新国产精品精品视频| 激情国产av做激情国产爱| 丰满肥臀大屁股熟妇激情视频| 艳妇乳肉豪妇荡乳| 国产超碰人人爱被ios解锁| 国产无遮挡又爽又黄大胸免费| 裸体女人高潮毛片| 精品无码av一区二区三区不卡 | 真人一进一出120秒试看| 欲香欲色天天综合和网| 国产乱人无码伦av在线a| 人妻aⅴ无码一区二区三区| 蜜臀av综合网| 久久免费精品国产72精品九九| 国产一区二区三区不卡在线观看| 欧美激情性做爰免费视频| 亚洲日韩欧洲无码av夜夜摸| 少妇被又大又粗猛烈进出视频| 国产精品免费无码二区| 免费看成人aa片无码视频羞羞网| 亚洲乱亚洲乱少妇无码| 双腿高潮抽搐喷白浆视频| 东京热无码国产精品| 欧美又粗又大xxxxbbbb疯狂| 99精品久久99久久久久| 久久天天躁狠狠躁夜夜av浪潮| 久久超碰极品视觉盛宴 | 欧美伊人色综合久久天天| 人妻体内射精一区二区三区|