在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MATK Antibody

  • 中文名稱:
    MATK兔多克隆抗體
  • 貨號:
    CSB-PA013519GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    CHK antibody; Csk homologous kinase antibody; Csk type protein tyrosine kinase antibody; CTK antibody; DKFZp434N1212 antibody; EC 2.7.10.2 antibody; Hematopoietic consensus tyrosine lacking kinase antibody; Hematopoietic consensus tyrosine-lacking kinase antibody; HHYLTK antibody; Hydroxyaryl protein kinase antibody; HYL antibody; HYL tyrosine kinase antibody; HYLTK antibody; Leukocyte carboxyl terminal src kinase related antibody; Lsk antibody; matK antibody; MATK_HUMAN antibody; Megakaryocyte associated tyrosine kinase antibody; Megakaryocyte associated tyrosine protein kinase antibody; Megakaryocyte-associated tyrosine-protein kinase antibody; MGC1708 antibody; MGC2101 antibody; Protein kinase HYL antibody; Tyrosine kinase MATK antibody; Tyrosine protein kinase CTK antibody; Tyrosine-protein kinase CTK antibody; Tyrosylprotein kinase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human MATK
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
  • 基因功能參考文獻:
    1. After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1. PMID: 21799000
    2. ERBB2 binds to the SH2 domain of CHK and inhibits cell growth in human breast tumor cell lines PMID: 12122014
    3. Overexpression of the Csk homologous kinase facilitates phosphorylation of akt/protein kinase b in breast neoplasms PMID: 12429987
    4. CHK Leu223 stabilizes the movement of the alphaC-helix of the protein tyrosine kinase PMID: 12782282
    5. Loss of CHK expression is associated with human brain tumors PMID: 15329911
    6. Nuclear multi-lobulation in late S phase, which is dependent on polymerization and depolymerization of microtubules, may be involved in nuclear Chk-induced inhibition of proliferation. PMID: 15748901
    7. striking functional differences between the Csk and Chk SH2 domains and revealed functional similarities between the Chk and Src SH2 domains PMID: 15890649
    8. This study describes for the first time the Src-independent actions of CHK and provides novel insights into CHK function in neural cells. PMID: 16168623
    9. Matk/CHK is not functionally redundant with Csk, and this tyrosine kinase plays an important role as a regulator of immunologic responses PMID: 16574955
    10. Findings indicate that the importance of the N-terminal domain to Chk-induced tyrosine phosphorylation in the nucleus, and implicate that nuclear tyrosine-phosphorylated proteins may contribute to inhibition of cell proliferation. PMID: 16707123
    11. Progesterone increases MATK in mast cells and reducs cell proliferation. PMID: 17492661
    12. These results reveal a potentially important role for CHK in Src activation and tumorigenicity in colon cancer cells. PMID: 17934522
    13. CHK is capable of inhibiting the CXCL12-CXCR4 pathway in neuroblastoma. PMID: 18292939

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
  • 蛋白家族:
    Protein kinase superfamily, Tyr protein kinase family, CSK subfamily
  • 組織特異性:
    Expressed in various myeloid cell lines, detected in brain and lung.
  • 數據庫鏈接:

    HGNC: 6906

    OMIM: 600038

    KEGG: hsa:4145

    STRING: 9606.ENSP00000378485

    UniGene: Hs.631845



主站蜘蛛池模板: 国产亚洲视频中文字幕97精品| 无套内内射视频网站| 国产私拍大尺度在线视频| 一本大道东京热无码| 亚洲熟妇无码另类久久久| 色一情一乱一伦| 国产精品多人p群无码| 亚洲中文在线播放一区| 亚洲一区二区无码偷拍| 欧美成妇人吹潮在线播放| 18禁精品久久久国产精品久久久| 中文字幕久久精品波多野结百度| 国自产偷精品不卡在线| 日本一卡二卡不卡视频查询| 成人亚洲a片v一区二区三区日本| 亚洲精品久久yy5099| 四虎成人国产精品永久在线 | 老熟妇乱子交视频一区| 天天爽天天狠久久久综合麻豆| 日韩中文字幕在线专区| 久久久久久a亚洲欧洲av冫| 精品人妻伦一二三区久久| 亚洲中文字幕永久在线全国| 亚洲精品一本之道高清乱码| 久久精品无码一区二区www| 无码毛片内射白浆视频| 蜜臀av色欲a片无码精品一区| 天堂在/线中文在线资源8| av第一福利网站| 色婷婷综合久久久久中文| 精品国产乱码久久久久夜深人妻 | 国产精品人妻系列21p| 高大丰满欧美熟妇hd| 精品国产成人网站一区在线| 日日摸天天爽天天爽视频| 苍井空亚洲精品aa片在线播放| 国产嘿嘿嘿视频在线观看| 国产三级视频在线观看视| 蜜臀av免费一区二区三区| 免费纯肉3d动漫无码网站| 亚洲性夜夜综合久久7777|